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W

Wai‐Hong Tham

The Walter and Eliza Hall Institute of Medical Research

42H指数
158论文数
6.4K被引数
收录论文 63
发表时间
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Antigen-Detected NMR for Minimal Epitope Engineering and Structure-Guided Selection of a NaV1.7-Selective Nanobody抗原检测NMR技术用于最小表位工程改造和结构指导的NaV1.7选择性纳米抗体的筛选
errAdvanced Science
IF14.1
err2026-09-07
err0
errOAAI
errJunyu Liu; Wanlin Chen; Ben Cristofori-Armstrong; Theo Crawford; Kai-En Chen; Peng Xie; Rainbow Wing Bo Chan; Yifei Zhu; Mimi Golder; Anneka Pereira Schmidt; Jennifer D. Naughton; Nicholas D. Condon; Åsa Andersson; Farhad Dehkhoda; Kirsten L. McMahon; Tabea Klasfauseweh; Ashvriya Thapa; Hue Tran; Poanna Tran; Sina Jami; Lotten Ragnarsson; Sebastian G. B. Furness; Jennifer R. Deuis; Brett M. Collins; Wai-Hong Tham; Indira Prasadam; Irina Vetter; Mehdi Mobli
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Assessing the effect of parasite antigen genetic diversity on performance of Plasmodium vivax serological exposure markers for malaria: a multicentre observational diagnostic accuracy study评估寄生虫抗原遗传多样性对间日疟原虫血清学暴露标志物在疟疾中性能的影响：一项多中心观察性诊断准确性研究
errThe Lancet Microbe
IF0
err2026-05-19
err0
errOAAI
errAlison Paolo N Bareng; Kenneth W Wu; Eizo Takashima; Dionne C Argyropoulos; Lauren Smith; Myo T Naung; Ramin Mazhari; Kael Schoffer; Nicholas Kiernan-Walker; Anju Abraham; Macie Lamont; Somya Mehra; Pailene S Lim; Jetsumon Sattabongkot; Wuelton Monteiro; Marcus Lacerda; Julie Healer; Chetan E Chitnis; Wai-Hong Tham; Takafumi Tsuboi
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Host iron deficiency protects against Plasmodium infection and drives parasite molecular reprofiling宿主铁缺乏可抵抗 *Plasmodium* 感染并驱动寄生虫分子重编程
errScience Advances
IF12.5
err2026-02-27
err0
errOAAI
errDanielle Clucas; Cavan Bennett; Rebecca Harding; Anne Pettikiriarachchi; Andrew Baldi; Louise M. Randall; Ryan Steel; Ronan Mellin; Melissa Hobbs; Sabrina Caiazzo; Martin N. Mwangi; Katherine L. Fielding; Peter F. Hickey; Tracey M. Baldwin; Daniela Amann-Zalcenstein; Samantha J. Emery-Corbin; Glory Mzembe; Ernest Moya; Sabine Braat; Aaron Jex; Ayse Y. Demir; Hans Verhoef; Kamija S. Phiri; Beverley-Ann Biggs; Wai-Hong Tham; Justin A. Boddey; Sant-Rayn Pasricha; Ricardo Ataíde
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Alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing
errmAbs
IF7.3
err2026-02-03
err0
errOAAI
errKathleen Zeglinski; Jakob Schuster; Jaison D Sa; Amy Adair; Jing Deng; Phillip Pymm; Matthew E. Ritchie; Rory Bowden; Wai-Hong Tham; Quentin Gouil
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Elevated SARS-CoV-2 IgG4 in plasma and mucosa following repeated mRNA boosters impact antibody functions to Omicron and sarbecoviruses重复mRNA加强针后血浆和黏膜中升高的SARS-CoV-2 IgG4对Omicron和sarbecoviruses的抗体功能产生影响
erreBioMedicine
IF10.8
err2025-12-20
err0
errOAAI
errKevin J. Selva; Wen Shi Lee; Alther L. Enriquez; L. Carissa Aurelia; Jennifer Audsley; Helen E. Kent; Emily M. Eriksson; Nicholas Kiernan-Walker; J. Judy Chang; Janine M. Trevillyan; Phillip Pymm; Wai-Hong Tham; Laura E. Downie; Adam K. Wheatley; Jennifer A. Juno; Stephen J. Kent; Amy W. Chung
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A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responses一种新型嵌合冠状病毒刺突疫苗，结合了SARS-CoV-2 RBD和来自HKU-1的支架结构域，能够诱导强烈的中和抗体反应
errnpj Vaccines
IF6.5
err2025-11-28
err0
errOAAI
errVeronica P. Zoest; Wen Shi Lee; Lydia Murdiyarso; Lauren Burmas; Phillip Pymm; Robyn Esterbauer; Andrew Kelly; Hannah G. Kelly; Isaac Barber-Axthelm; James P. Cooney; Kathryn C. Davidson; Merle Dayton; Courtney E. McAleese; Marianne Gillard; Karen Hughes; Martina L. Jones; Marc Pellegrini; Wai-Hong Tham; Ben Hughes; Stephen J. Kent; Adam K. Wheatley; Jennifer A. Juno; Hyon-Xhi Tan
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Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex恶性疟原虫Pfs230和Pfs48/45受精复合物的内源性cryo-EM结构
errScience
IF45.8
err2025-07-31
err0
PREAI
errMelanie H. Dietrich; Jill Chmielewski; Li-Jin Chan; Li Lynn Tan; Amy Adair; Frankie M. T. Lyons; Mikha Gabriela; Sash Lopaticki; Toby A. Dite; Laura F. Dagley; Lucia Pazzagli; Priya Gupta; Mohd Kamil; Ashley M. Vaughan; Rattanaporn Rojrung; Anju Abraham; Ramin Mazhari; Rhea J. Longley; Kathleen Zeglinski; Quentin Gouil; Ivo Mueller; Stewart A. Fabb; Rekha Shandre-Mugan; Colin W. Pouton; Alisa Glukhova; Shabih Shakeel; Wai-Hong Tham
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Nanobodies against Cavin1 reveal structural flexibility and regulated interactions of its N-terminal coiled-coil domain抗Cavin1的纳米抗体揭示了其N端卷曲coil结构域的结构柔韧性和调控相互作用
errJOURNAL OF CELL SCIENCE
IF3.6
err2025-04-28
err0
errOAAI
errGao, Ya; Tillu, Vikas A.; Wu, Yeping; Rae, James; Hall, Thomas E.; Chen, Kai-En; Weeratunga, Saroja; Guo, Qian; Livingstone, Emma; Tham, Wai-Hong; Parton, Robert G.
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Stabilized designs of the malaria adhesin protein PvRB use as a potential diagnostic for Plasmodium vivax
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-02-01
err0
errOAAI
errSa, Jaison; Krauss, Lucas; Smith, Lauren; Andrea, Laura D. '; Chan, Li-Jin; Abraham, Anju; Kiernan-Walker, Nicholas; Mazhari, Ramin; Lamont, Macie; Lim, Pailene S.; Sattabongkot, Jetsumon; Lacerda, Marcus VG.; Wini, Lyndes; Mueller, Ivo; Longley, Rhea J.; Pymm, Phillip; Fleishman, Sarel J.; Tham, Wai-Hong
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Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages
errNATURE COMMUNICATIONS
IF15.7
err2024-12-04
err0
errOAAI
errWinnicki, Anna C.; Dietrich, Melanie H.; Yeoh, Lee M.; Carias, Lenore L.; Roobsoong, Wanlapa; Drago, Chiara L.; Malachin, Alyssa N.; Redinger, Karli R.; Feufack-Donfack, Lionel Brice; Baldor, Lea; Jung, Nicolai C.; Mclaine, Olivia S.; Skomorovska-Prokvolit, Yelenna; Orban, Agnes; Opi, D. Herbert; Kirtley, Payton; Nielson, Kiersey; Aleshnick, Maya; Zanghi, Gigliola; Rezakhani, Nastaran; Vaughan, Ashley M.; Wilder, Brandon K.; Sattabongkot, Jetsumon; Tham, Wai-Hong; Popovici, Jean; Beeson, James G.; Bosch, Jurgen; King, Christopher L.
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Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1 (vol 15, 5219, 2024)芳基氨基乙酰胺通过靶向脂质转移蛋白PfSTART1 (vol 15，5219，2024) 防止恶性疟原虫环发育
errNATURE COMMUNICATIONS
IF15.7
err2024-09-30
err0
errOAAI
errDans, Madeline G.; Boulet, Coralie; Watson, Gabrielle M.; Nguyen, William; Dziekan, Jerzy M.; Evelyn, Cindy; Reaksudsan, Kitsanapong; Mehra, Somya; Razook, Zahra; Geoghegan, Niall D.; Mlodzianoski, Michael J.; Goodman, Christopher Dean; Ling, Dawson B.; Jonsdottir, Thorey K.; Tong, Joshua; Famodimu, Mufuliat Toyin; Kristan, Mojca; Pollard, Harry; Stewart, Lindsay B.; Brandner-Garrod, Luke; Sutherland, Colin J.; Delves, Michael J.; Mcfadden, Geoffrey I.; Barry, Alyssa E.; Crabb, Brendan S.; de Koning-Ward, Tania F.; Rogers, Kelly L.; Cowman, Alan F.; Tham, Wai-Hong; Sleebs, Brad E.; Gilson, Paul R.
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The biology and pathogenesis of vivax malaria
errTrends in Parasitology
IF6.6
err2024-07-01
err3
PREAI
errAnstey, Nicholas M.; Tham, Wai-Hong; Shanks, G. Dennis; Poespoprodjo, Jeanne R.; Russell, Bruce M.; Kho, Steven
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Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1芳基氨基乙酰胺通过靶向脂质转移蛋白PfSTART1阻止恶性疟原虫环的发展
errNATURE COMMUNICATIONS
IF15.7
err2024-06-18
err5
errOAAI
errDans, Madeline G.; Boulet, Coralie; Watson, Gabrielle M.; Nguyen, William; Dziekan, Jerzy M.; Evelyn, Cindy; Reaksudsan, Kitsanapong; Mehra, Somya; Razook, Zahra; Geoghegan, Niall D.; Mlodzianoski, Michael J.; Goodman, Christopher Dean; Ling, Dawson B.; Jonsdottir, Thorey K.; Tong, Joshua; Famodimu, Mufuliat Toyin; Kristan, Mojca; Pollard, Harry; Stewart, Lindsay B.; Brandner-Garrod, Luke; Sutherland, Colin J.; Delves, Michael J.; Mcfadden, Geoffrey I.; Barry, Alyssa E.; Crabb, Brendan S.; de Koning-Ward, Tania F.; Rogers, Kelly L.; Cowman, Alan F.; Tham, Wai-Hong; Sleebs, Brad E.; Gilson, Paul R.
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err收藏
Human coronavirus OC43 nanobody neutralizes virus and protects mice from infection
errJOURNAL OF VIROLOGY
IF3.8
err2024-06-13
err0
errOAAI
errAdair, Amy; Tan, Li Lynn; Feng, Jackson; Girkin, Jason; Bryant, Nathan; Wang, Mingyang; Mordant, Francesca; Chan, Li-Jin; Bartlett, Nathan W.; Subbarao, Kanta; Pymm, Phillip; Tham, Wai-Hong
err分享
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Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein靶向恶性疟原虫星形相关脂质转移1蛋白的芳基氨基乙酰胺的活性精制
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-04-01
err4
errOAAI
errNguyen, William; Boulet, Coralie; Dans, Madeline G.; Loi, Katie; Jarman, Kate E.; Watson, Gabrielle M.; Tham, Wai-Hong; Fairhurst, Kate J.; Yeo, Tomas; Fidock, David A.; Wittlin, Sergio; Chowdury, Mrittika; de Koning-Ward, Tania F.; Chen, Gong; Yan, Dandan; Charman, Susan A.; Baud, Delphine; Brand, Stephen; Jackson, Paul F.; Cowman, Alan F.; Gilson, Paul R.; Sleebs, Brad E.
err分享
err收藏
A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts (vol 25, pg 1223, 2023)
errNATURE CELL BIOLOGY
IF19.1
err2023-12-18
err0
errOAAI
errChen, J.; Neil, J. A.; Tan, J. P.; Rudraraju, R.; Mohenska, M.; Sun, Y. B. Y.; Walters, E.; Bediaga, N. G.; Sun, G.; Zhou, Y.; Li, Y.; Drew, D.; Pymm, P.; Tham, W. H.; Wang, Y.; Rossello, F. J.; Nie, G.; Liu, X.; Subbarao, K.; Polo, J. M.
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Antibody Fc-binding profiles and ACE2 affinity to SARS-CoV-2 RBD variants
errMEDICAL MICROBIOLOGY AND IMMUNOLOGY
IF3
err2023-07-21
err11
errOAAI
errHaycroft, Ebene R.; Davis, Samantha K.; Ramanathan, Pradhipa; Lopez, Ester; Purcell, Ruth A.; Tan, Li Lynn; Pymm, Phillip; Wines, Bruce D.; Hogarth, P. Mark; Wheatley, Adam K.; Juno, Jennifer A.; Redmond, Samuel J.; Gherardin, Nicholas A.; Godfrey, Dale I.; Tham, Wai-Hong; Selva, Kevin John; Kent, Stephen J.; Chung, Amy W.
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A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblastsSARS-CoV-2感染的胎盘模型揭示了合体滋养层细胞的ACE2-dependent易感性和分化障碍
errNATURE CELL BIOLOGY
IF19.1
err2023-07-13
err16
errOAAI
errChen, J.; Neil, J. A.; Tan, J. P.; Rudraraju, R.; Mohenska, M.; Sun, Y. B. Y.; Walters, E.; Bediaga, N. G.; Sun, G.; Zhou, Y.; Li, Y.; Drew, D.; Pymm, P.; Tham, W. H.; Rossello, F. J.; Nie, G.; Liu, X.; Subbarao, K.; Polo, J. M.
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Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment
errSTEM CELL REPORTS
IF5.1
err2023-06-01
err6
errOAAI
errRudraraju, Rajeev; Gartner, Matthew J.; Neil, Jessica A.; Stout, Elizabeth S.; Chen, Joseph; Needham, Elise J.; See, Michael; Mackenzie-Kludas, Charley; Lee, Leo Yi Yang; Wang, Mingyang; Pointer, Hayley; Karavendzas, Kathy; Abu-Bonsrah, Dad; Drew, Damien; Sun, Yu Bo Yang; Tan, Jia Ping; Sun, Guizhi; Salavaty, Adrian; Charitakis, Natalie; Nim, Hieu T.; Currie, Peter D.; Tham, Wai-Hong; Porrello, Enzo; Polo, Jose M.; Humphrey, Sean J.; Ramialison, Mirana; Elliott, David A.; Subbarao, Kanta
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Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 (vol 13, 889372, 2022)Fc工程ACE2-Fc是一种有效的多功能剂靶向SARS-CoV2 (vol 13，889372，2022)
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-01-10
err0
errOAAI
errWines, Bruce D.; Kurtovic, Liriye; Trist, Halina M.; Esparon, Sandra; Lopez, Ester; Chappin, Klasina; Chan, Li-Jin; Mordant, Francesca L.; Lee, Wen Shi; Gherardin, Nicholas A.; Patel, Sheila K.; Hartley, Gemma E.; Pymm, Phillip; Cooney, James P.; Beeson, James G.; Godfrey, Dale I.; Burrell, Louise M.; van Zelm, Menno C.; Wheatley, Adam K.; Chung, Amy W. W.; Tham, Wai-Hong; Subbarao, Kanta; Kent, Stephen J.; Hogarth, P. Mark
err分享
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研究方向

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合作学者
合作期刊
R
Robert G. Parton
H 指数: 149 · 论文数: 706
B
Beatrice H. Hahn
H 指数: 140 · 论文数: 661
P
Pamela A. Silver
H 指数: 116 · 论文数: 525
A
Alan F. Cowman
H 指数: 113 · 论文数: 462
D
Dale I. Godfrey
H 指数: 105 · 论文数: 465
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