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M

Martin Ebeling

F. Hoffmann-La Roche Ltd
H指数:37
被引数:5,249

个人简介

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工作经历

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荣誉奖项

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STING activation induces polarized cytokine secretion of IFN-β and IL-17A promoting photoreceptor death and choroidal disruption in age-related macular degeneration

STING激活诱导IFN-β和IL-17A的极化细胞因子分泌，促进视网膜感光细胞死亡和老年性黄斑变性中的脉络膜破坏。

Cell Death & Disease
IF9.6
2026-02-270
OAAI
Chao Huang; Vishnu Suresh Babu; Sridhar Bammidi; Jakob N. Arnold; Martin Ebeling; Gabriella Widmer; Pamela Strassburger; Mirjana Lazendic; Sabine Grüner; Janis Koester; Puja Dutta; Stacey Hose; Sonali Singh; Pooja Gautam; Eleonora M. Lad; Peter D. Westenskow; Oksana Kutsyr; Karl G. Csaky; Sayan Ghosh; Srinivasa R. Sripathi; Alan D. Proia; Miguel Flores-Bellver; Debasish Sinha; Derrick Feenstra
Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct
NATURE COMMUNICATIONS
IF15.7
2023-04-1216
OAAI
Gehrlein, Alexandra; Udayar, Vinod; Anastasi, Nadia; Morella, Martino L. L.; Ruf, Iris; Brugger, Doris; von der Mark, Sophia; Thoma, Ralf; Rufer, Arne; Heer, Dominik; Pfahler, Nina; Jochner, Anton; Niewoehner, Jens; Wolf, Luise; Fueth, Matthias; Ebeling, Martin; Villasenor, Roberto; Zhu, Yanping; Deen, Matthew C. C.; Shan, Xiaoyang; Ehsaei, Zahra; Taylor, Verdon; Sidransky, Ellen; Vocadlo, David J. J.; Freskgard, Per-Ola; Jagasia, Ravi
A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies

用于治疗性重组抗体毒理学测试的人源化小型猪模型

NATURE BIOMEDICAL ENGINEERING
IF26.6
2022-09-2215
OAAI
Flisikowska, Tatiana; Egli, Jerome; Flisikowski, Krzysztof; Stumbaum, Marlene; Kueng, Erich; Ebeling, Martin; Schmucki, Roland; Georges, Guy; Singer, Thomas; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Wolf, Eckhard; Weber, Felix; Schnieke, Angelika; Iglesias, Antonio
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology
CELL REPORTS MEDICINE
IF10.6
2021-08-0130
OAAI
Pandya, Nikhil J.; Wang, Congwei; Costa, Veronica; Lopatta, Paul; Meier, Sonja; Zampeta, F. Isabella; Punt, A. Mattijs; Mientjes, Edwin; Grossen, Philip; Distler, Tania; Tzouros, Manuel; Marti, Yasmina; Banfai, Balazs; Patsch, Christoph; Rasmussen, Soren; Hoener, Marius; Berrera, Marco; Kremer, Thomas; Dunkley, Tom; Ebeling, Martin; Distel, Ben; Elgersma, Ype; Jagasia, Ravi
Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-07-25360
OAAI
Ratni, Hasane; Ebeling, Martin; Baird, John; Bendels, Stefanie; Bylund, Johan; Chen, Karen S.; Denk, Nora; Feng, Zhihua; Green, Luke; Guerard, Melanie; Jablonski, Philippe; Jacobsen, Bjoern; Khwaja, Omar; Kletzl, Heidemarie; Ko, Chien-Ping; Kustermann, Stefan; Marquet, Anne; Metzger, Friedrich; Mueller, Barbara; Naryshkin, Nikolai A.; Paushkin, Sergey V.; Pinard, Emmanuel; Poirier, Agnes; Reutlinger, Michael; Weetall, Marla; Zeller, Andreas; Zhao, Xin; Mueller, Lutz
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes
NATURE COMMUNICATIONS
IF15.7
2018-05-2358
OAAI
Garcia-Lopez, Amparo; Tessaro, Francesca; Jonker, Hendrik R. A.; Wacker, Anna; Richter, Christian; Comte, Arnaud; Berntenis, Nikolaos; Schmucki, Roland; Hatje, Klas; Petermann, Olivier; Chiriano, Gianpaolo; Perozzo, Remo; Sciarra, Daniel; Konieczny, Piotr; Faustino, Ignacio; Fournet, Guy; Orozco, Modesto; Artero, Ruben; Metzger, Friedrich; Ebeling, Martin; Goekjian, Peter; Joseph, Benoit; Schwalbe, Harald; Scapozza, Leonardo

研究方向

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U
Ulrich Certa
H 指数:43论文数:176被引数:6,730
J
Jitao David Zhang
H 指数:27论文数:101被引数:4,825
R
Roland Schmucki
H 指数:20论文数:78被引数:2,107
E
Erich Küng
H 指数:12论文数:27被引数:722
M
Marco Berrera
H 指数:20论文数:64被引数:1,639
T
Thomas P. Singer
H 指数:79论文数:542被引数:2.2万
R
Ravi Jagasia
H 指数:32论文数:93被引数:5,606
A
Anna Kiialainen
H 指数:25论文数:91被引数:5,479
A
Antonio Iglesias
H 指数:34论文数:89被引数:6,577
K
Klas Hatje
H 指数:18论文数:66被引数:1,544