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A bottom-up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors Rodriguez-Iglesias, Noelia; Paris, Inaki; Valero, Jorge; Canas-Zabala, Lorena; Carretero, Alejandro; Hatje, Klas; Zhang, Jitao David; Patsch, Christoph; Britschgi, Markus; Gutbier, Simon; Sierra, Amanda 分享 收藏
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A randomized, double-blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcerative colitis Klughammer, Barbara; Piali, Luca; Nica, Alexandra; Nagel, Sandra; Bailey, Lorna; Jochum, Christoph; Ignatenko, Stanislav; Blauer, Angela; Danilin, Sabrina; Gulati, Pratiksha; Hayward, Joanne; Scepanovic, Petar; Zhang, Jitao David; Bhosale, Satish; Chong, Chui Fung; Christ, Andreas 分享 收藏
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Discovery of a first-in-class orally available HBV cccDNA inhibitor 发现一流的口服HBV cccDNA抑制剂 Wang, Li; Zhu, Qihui; Zhang, Jitao David; Zhang, Yaling; Ni, Xiaoju; Xiang, Kunlun; Jiang, Jiaxi; Li, Baocun; Yu, Youjun; Hu, Hui; Zhang, Meifang; Wu, Waikwong; Zeng, Jing; Yan, Zhipeng; Dai, Jieyu; Sun, Kai; Zhang, Xin; Chen, Dongdong; Feng, Song; Sach-Peltason, Lisa; Young, John A. T.; Gao, Lu 分享 收藏
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Discovery of Novel cccDNA Reducers toward the Cure of Hepatitis B Virus Infection Chen, Dongdong; Tan, Xuefei; Chen, Wenming; Liu, Yongfu; Li, Chao; Wu, Jun; Zheng, Jiamin; Shen, Hong C.; Zhang, Meifang; Wu, Waikwong; Wang, Lin; Xiong, Jing; Dai, Jieyu; Sun, Kai; Zhang, Jitao David; Xiang, Kunlun; Li, Baocun; Ni, XiaoJu; Zhu, Qihui; Gao, Lu; Wang, Li; Feng, Song 分享 收藏
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Optimization of the TeraTox Assay for Preclinical Teratogenicity Assessment Jaklin, Manuela; Zhang, Jitao David; Schaefer, Nicole; Clemann, Nicole; Barrow, Paul; Kueng, Erich; Sach-Peltason, Lisa; McGinnis, Claudia; Leist, Marcel; Kustermann, Stefan 分享 收藏
Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research Maedler, Sophia Clara; Julien-Laferriere, Alice; Wyss, Luis; Phan, Miroslav; Sonrel, Anthony; Kang, Albert S. W.; Ulrich, Eric; Schmucki, Roland; Zhang, Jitao David; Ebeling, Martin; Badi, Laura; Kam-Thong, Tony; Schwalie, Petra C.; Hatje, Klas 分享 收藏
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Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia Reich, Marvin; Paris, Inaki; Ebeling, Martin; Dahm, Nadine; Schweitzer, Christophe; Reinhardt, Dieter; Schmucki, Roland; Prasad, Megana; Kochl, Fabian; Leist, Marcel; Cowley, Sally A.; Zhang, Jitao David; Patsch, Christoph; Gutbier, Simon; Britschgi, Markus 分享 收藏
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Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells 在基因组编辑的hPSC-内皮细胞中通过化学基因组学筛选鉴定内皮细胞屏障的诱导剂 Roudnicky, Filip; Zhang, Jitao David; Kim, Bo Kyoung; Pandya, Nikhil J.; Lan, Yanjun; Sach-Peltason, Lisa; Ragelle, Heloise; Strassburger, Pamela; Gruener, Sabine; Lazendic, Mirjana; Uhles, Sabine; Revelant, Franco; Eidam, Oliv; Sturm, Gregor; Kueppers, Verena; Christensen, Klaus; Goldstein, Leonard D.; Tzouros, Manuel; Banfai, Balazs; Modrusan, Zora; Graf, Martin; Patsch, Christoph; Burcin, Mark; Meyer, Claas A.; Westenskow, Peter D.; Cowan, Chad A. 分享 收藏
Signaling pathways predisposing to chronic kidney disease progression Zaidan, Mohamad; Burtin, Martine; Zhang, Jitao David; Blanc, Thomas; Barre, Pauline; Garbay, Serge; Nguyen, Clement; Vasseur, Florence; Yammine, Lucie; Germano, Serena; Badi, Laura; Gubler, Marie-Claire; Gallazzini, Morgan; Friedlander, Gerard; Pontoglio, Marco; Terzi, Fabiola 分享 收藏
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Assessment of network module identification across complex diseases 跨复杂疾病的网络模块识别评估 Choobdar, Sarvenaz; Ahsen, Mehmet E.; Crawford, Jake; Tomasoni, Mattia; Fang, Tao; Lamparter, David; Lin, Junyuan; Hescott, Benjamin; Hu, Xiaozhe; Mercer, Johnathan; Natoli, Ted; Narayan, Rajiv; Aicheler, Fabian; Amoroso, Nicola; Arenas, Alex; Azhagesan, Karthik; Baker, Aaron; Banf, Michael; Batzoglou, Serafim; Baudot, Anais; Bellotti, Roberto; Bergmann, Sven; Boroevich, Keith A.; Brun, Christine; Cai, Stanley; Caldera, Michael; Calderone, Alberto; Cesareni, Gianni; Chen, Weiqi; Chichester, Christine; Cowen, Lenore; Cui, Hongzhu; Phuong Dao; De Domenico, Manlio; Dhroso, Andi; Didier, Gilles; Divine, Mathew; del Sol, Antonio; Feng, Xuyang; Flores-Canales, Jose C.; Fortunato, Santo; Gitter, Anthony; Gorska, Anna; Guan, Yuanfang; Guenoche, Alain; Gomez, Sergio; Hamza, Hatem; Hartmann, Andras; He, Shan; Heijs, Anton; Heinrich, Julian; Hu, Ying; Huang, Xiaoqing; Hughitt, V. Keith; Jeon, Minji; Jeub, Lucas; Johnson, Nathan T.; Joo, Keehyoung; Joung, InSuk; Jung, Sascha; Kalko, Susana G.; Kamola, Piotr J.; Kang, Jaewoo; Kaveelerdpotjana, Benjapun; Kim, Minjun; Kim, Yoo-Ah; Kohlbacher, Oliver; Korkin, Dmitry; Krzysztof, Kiryluk; Kunji, Khalid; Kutalik, Zoltan; Lage, Kasper; Lang-Brown, Sean; Thuc Duy Le; Lee, Jooyoung; Lee, Sunwon; Lee, Juyong; Li, Dong; Li, Jiuyong; Liu, Lin; Loizou, Antonis; Luo, Zhenhua; Lysenko, Artem; Ma, Tianle; Mall, Raghvendra; Marbach, Daniel; Mattia, Tomasoni; Medvedovic, Mario; Menche, Jorg; Micarelli, Elisa; Monaco, Alfonso; Mueller, Felix; Narykov, Oleksandr; Norman, Thea; Park, Sungjoon; Perfetto, Livia; Perrin, Dimitri; Pirro, Stefano; Przytycka, Teresa M.; Qian, Xiaoning; Raman, Karthik; Ramazzotti, Daniele; Ramsahai, Emilie; Ravindran, Balaraman; Rennert, Philip; Saez-Rodriguez, Julio; Scharfe, Charlotta; Sharan, Roded; Shi, Ning; Shin, Wonho; Shu, Hai; Sinha, Himanshu; Slonim, Donna K.; Spinelli, Lionel; Srinivasan, Suhas; Subramanian, Aravind; Suver, Christine; Szklarczyk, Damian; Tangaro, Sabina; Thiagarajan, Suresh; Tichit, Laurent; Tiede, Thorsten; Tripathi, Beethika; Tsherniak, Aviad; Tsunoda, Tatsuhiko; Turei, Denes; Ullah, Ehsan; Vahedi, Golnaz; Valdeolivas, Alberto; Vivek, Jayaswal; von Mering, Christian; Waagmeester, Andra; Wang, Bo; Wang, Yijie; Weir, Barbara A.; White, Shana; Winkler, Sebastian; Xu, Ke; Xu, Taosheng; Yan, Chunhua; Yang, Liuqing; Yu, Kaixian; Yu, Xiangtian; Zaffaroni, Gaia; Zaslavskiy, Mikhail; Zeng, Tao; Zhang, Jitao D.; Zhang, Lu; Zhang, Weijia; Zhang, Lixia; Zhang, Xinyu; Zhang, Junpeng; Zhou, Xin; Zhou, Jiarui; Zhu, Hongtu; Zhu, Junjie; Zuccon, Guido; Stolovitzky, Gustavo; Kutalik, Zoltan; Lage, Kasper; Slonim, Donna K.; Saez-Rodriguez, Julio; Cowen, Lenore J.; Bergmann, Sven; Marbach, Daniel 分享 收藏
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