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J

Jinhua Wang

dana-farber cancer institute

40H指数
164论文数
6.5K被引数
收录论文 67
发表时间
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Structure-Guided Design of Potent and Selective Covalent Inhibitors Targeting the SARS-CoV-2 Papain-like Protease基于结构的强效且选择性共价抑制剂的设计，靶向SARS-CoV-2半胱天冬酶样蛋白酶
errJournal of Medicinal Chemistry
IF6.8
err2026-01-20
err0
PREAI
errMona Sharafi; Wei Pin Teh; Jeremy Green; Paul S. Charifson; Jinhua Wang; Orville A. Pemberton; Amanda M. Nevins; Ming Lye; Xiaoxi Liu; Anthony C. Varca; Callum D. Owen; Kimberley Morsheimer; Alan Wacquiez; Christpher Dawson; Christopher Steuber; Jennifer Smith; Nicholas M. Girardi; Robert S. Magin; Jarrod A. Marto; Mohsan Saeed; Rob A. Davey; David Hardee; Teresa I. Ng; Mark N. Namchuk; Sara J. Buhrlage
err分享
err收藏
Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2026-01-01
err0
PREAI
errHatcher, John M.; Liu, Shirong; Kofides, Amanda; Canning, Alexa; Pizzarella, Dominic; Liu, Xia; Tsakmaklis, Nickolas; Guerrera, Maria; Patterson, Christopher; Guijosa, Alberto; Gokhale, Prafulla; Hunter, Zachary; Sarosiek, Shayna; Castillo, Jorge; Wang, Jinhua; Buhrlage, Sara J.; Treon, Steven P.
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Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas作者更正：FGFR 突变和共突变的多样化景观表明儿童低级别胶质瘤中存在潜在的治疗策略
errNature Communications
IF15.7
err2025-10-09
err0
errOAAI
errApril A. Apfelbaum; Eric Morin; Dominik Sturm; Georges Ayoub; Jeromy DiGiacomo; Sher Bahadur; Bhavyaa Chandarana; Phoebe C. Power; Margaret M. Cusick; Dana Novikov; Prem Prabhakar; Robert E. Jones; Jayne Vogelzang; Connor C. Bossi; Seth Malinowski; Lewis M. Woodward; Tania A. Jones; John Jeang; Sarah W. Lamson; Jared Collins; Kelly Y. Cai; Jacquelyn S. Jones; Sehee Oh; Hyesung Jeon; Jinhua Wang; Amy Cameron; Patrick Rechter; Angela De Leon; Karthikeyan Murugesan; Meagan Montesion; Lee A. Albacker; Shakti H. Ramkissoon; Cornelis M. van Tilburg; Emily C. Hardin; Philipp Sievers; Felix Sahm; Kee Kiat Yeo; Tom Rosenberg; Susan N. Chi; Karen D. Wright; Steven Hébert; Sydney Peck; Alberto Picca; Valérie Larouche; Samuele Renzi; Sara J. Buhrlage; Tejus A. Bale; Amy A. Smith; Mehdi Touat; Nada Jabado; Eric S. Fischer; Michael J. Eck; Lissa Baird; Olaf Witt; Claudia L. Kleinman; Quang-De Nguyen; Denise Sheer; Sanda Alexandrescu; David T. W. Jones; Keith L. Ligon; Pratiti Bandopadhayay
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A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomasFGFR变异和共突变多样性的景观表明儿科低级别胶质瘤存在潜在的治疗策略
errNature Communications
IF15.7
err2025-07-31
err0
errOAAI
errApril A. Apfelbaum; Eric Morin; Dominik Sturm; Georges Ayoub; Jeromy DiGiacomo; Sher Bahadur; Bhavyaa Chandarana; Phoebe C. Power; Margaret M. Cusick; Dana Novikov; Prem Prabhakar; Robert E. Jones; Jayne Vogelzang; Connor C. Bossi; Seth Malinowski; Lewis M. Woodward; Tania A. Jones; John Jeang; Sarah W. Lamson; Jared Collins; Kelly Y. Cai; Jacquelyn S. Jones; Sehee Oh; Hyesung Jeon; Jinhua Wang; Amy Cameron; Patrick Rechter; Angela De Leon; Karthikeyan Murugesan; Meagan Montesion; Lee A. Albacker; Shakti H. Ramkissoon; Cornelis M. van Tilburg; Emily C. Hardin; Philipp Sievers; Felix Sahm; Kee Kiat Yeo; Tom Rosenberg; Susan N. Chi; Karen D. Wright; Steven Hébert; Sydney Peck; Alberto Picca; Valérie Larouche; Samuele Renzi; Sara J. Buhrlage; Tejus A. Bale; Amy A. Smith; Mehdi Touat; Nada Jabado; Eric S. Fischer; Michael J. Eck; Lissa Baird; Olaf Witt; Claudia L. Kleinman; Quang-De Nguyen; Denise Sheer; Sanda Alexandrescu; David T. W. Jones; Keith L. Ligon; Pratiti Bandopadhayay
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Plasmodium falciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activityPlasmodium falciparum蛋白激酶6和血红素晶体的形成被一种具有抗疟疾活性的II型人源激酶抑制剂所抑制
errCell Chemical Biology
IF7.2
err2025-07-07
err0
PREAI
errFlore Nardella; Tiantian Jiang; Lushun Wang; Monica J. Bohmer; Subhoja Chakraborty; John Okombo; Jaeson Calla; Tatiane Macedo Silva; Samuel Pazicky; Jianwei Che; Jin Jeon; Evie Vincent; Nonlawat Boonyalai; Rachael Coyle; Mairi J. Buchanan; Samuel Schaefer; Daisy Chen; Amaan Khan; Emily Mayville; Mariana Laureano De Souza; Mayland Treat; Jordan Charlton; Patrick K. Tumwebaze; Seth Tjia; Lukas Montejo; Karen Cover; Philip J. Rosenthal; Roland A. Cooper; Zbynek Bozdech; Marcus C.S. Lee; Ratna Chakrabarti; Sanjay A. Desai; David A. Fidock; Jinhua Wang; Nathanael S. Gray; Elizabeth A. Winzeler; Debopam Chakrabarti
err分享
err收藏
Sophoricoside Inhibited Glioblastoma Cell Progression Through Activated AMP-Activated Protein Kinase (AMPK)
errMOLECULAR CARCINOGENESIS
IF3.2
err2025-01-29
err0
PREAI
errWang, Changquan; Xiong, Xuehui; Li, Chang; Lu, Yuan; Zhang, Yan; Tian, Han; Xu, Chunlin; Ma, Tengfei; Wang, Jinhua; Zhang, Jianqing; Wang, Lei
err分享
err收藏
Crude polysaccharides of Helvella leucopus induces myogenic differentiation of C2C12 cells and raises levels of genes involved in mitochondrial dynamics
errJOURNAL OF FUNCTIONAL FOODS
IF4
err2024-08-01
err0
errOAAI
errFang, Ziyang; Li, Ying; Chen, Hongjie; Lian, Chunrong; Zhang, Xin; Wang, Jinhua; Zhou, Zhongbo
err分享
err收藏
The dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma双重HCK/BTK抑制剂KIN-8194损害BTKi抗性套细胞淋巴瘤的生长和整合素介导的粘附
errLEUKEMIA
IF13.4
err2024-03-07
err0
errOAAI
errLantermans, Hildo C.; Ma, Fangxue; Kuil, Annemieke; van Kesteren, Sanne; Yasinoglu, Sevtap; Yang, Guang; Buhrlage, Sara J.; Wang, Jinhua; Gray, Nathanael S.; Kersten, Marie Jose; Treon, Steven P.; Pals, Steven T.; Spaargaren, Marcel
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err收藏
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases发现对人类激酶具有选择性的有效抗疟疾II型激酶抑制剂
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-01-12
err0
PREAI
errWang, Lushun; Bohmer, Monica J.; Wang, Jinhua; Nardella, Flore; Calla, Jaeson; De Souza, Mariana Laureano; Schindler, Kyra A.; Montejo, Lukas; Mittal, Nimisha; Rocamora, Frances; Treat, Mayland; Charlton, Jordan T.; Tumwebaze, Patrick K.; Rosenthal, Philip J.; Cooper, Roland A.; Chakrabarti, Ratna; Winzeler, Elizabeth A.; Chakrabarti, Debopam; Gray, Nathanael S.
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err收藏
Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader用有效和选择性的粘合剂和降解剂靶向黑暗脂质激酶PIP4K2C
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-03-27
err2
PREAI
errTeng, Mingxing; Jiang, Jie; Wang, Eric S.; Geng, Qixiang; Toenjes, Sean T.; Donovan, Katherine A.; Mageed, Nada; Yue, Hong; Nowak, Radoslaw P.; Wang, Jinhua; Fischer, Eric D.; Manz, Theresa S.; Cantley, Lewis C.; Gray, Nathanael S.
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err收藏
Human Polo-like Kinase Inhibitors as Antiplasmodials
errACS INFECTIOUS DISEASES
IF3.8
err2023-03-15
err3
errOAAI
errBohmer, Monica J.; Wang, Jinhua; Istvan, Eva S.; Luth, Madeline R.; Collins, Jennifer E.; Huttlin, Edward L.; Wang, Lushun; Mittal, Nimisha; Hao, Mingfeng; Kwiatkowski, Nicholas P.; Gygi, Steven P.; Chakrabarti, Ratna; Deng, Xianming; Goldberg, Daniel E.; Winzeler, Elizabeth A.; Gray, Nathanael S.; Chakrabarti, Debopam
err分享
err收藏
Anti-SARS-CoV-2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID-19 therapy
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2022-09-28
err18
errOAAI
errBoytz, RuthMabel; Slabicki, Mikolaj; Ramaswamy, Sita; Patten, J. J.; Zou, Charles; Meng, Chengcheng; Hurst, Brett L.; Wang, Jinhua; Nowak, Radoslaw P.; Yang, Priscilla L.; Sattler, Martin; Stone, Richard M.; Griffin, James D.; Gray, Nathanael S.; Gummuluru, Suryaram; Davey, Robert A.; Weisberg, Ellen
err分享
err收藏
Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-08-01
err2
errOAAI
errLi, Zhengnian; Ishida, Ryosuke; Liu, Yan; Wang, Jinhua; Li, Yina; Gao, Yang; Jiang, Jie; Che, Jianwei; Sheltzer, Jason M.; Robers, Matthew B.; Zhang, Tinghu; Westover, Kenneth D.; Nabet, Behnam; Gray, Nathanael S.
err分享
err收藏
A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas
errBLOOD ADVANCES
IF7.1
err2022-06-03
err7
errOAAI
errMunshi, Manit; Liu, Xia; Kofides, Amanda; Tsakmaklis, Nickolas; Guerrera, Maria Luisa; Hunter, Zachary R.; Palomba, M. Lia; Argyropoulos, Kimon, V; Patterson, Christopher J.; Canning, Alexa G.; Meid, Kirsten; Gustine, Joshua; Branagan, Andrew R.; Flynn, Catherine A.; Sarosiek, Shayna; Castillo, Jorge J.; Wang, Jinhua; Buhrlage, Sara J.; Gray, Nathanael S.; Munshi, Nikhil C.; Anderson, Kenneth C.; Treon, Steven P.; Yang, Guang
err分享
err收藏
Prospects for Antibacterial Discovery and Development抗菌药物的发现和发展前景
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2021-12-03
err58
errOAAI
errPrivalsky, Thomas M.; Soohoo, Alexander M.; Wang, Jinhua; Walsh, Christopher T.; Wright, Gerard D.; Gordon, Eric M.; Gray, Nathanael S.; Khosla, Chaitan
err分享
err收藏
Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation
errNATURE COMMUNICATIONS
IF15.7
err2021-11-16
err20
errOAAI
errKaltheuner, Ines H.; Anand, Kanchan; Moecking, Jonas; Duester, Robert; Wang, Jinhua; Gray, Nathanael S.; Geyer, Matthias
err分享
err收藏
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
errELIFE
IF0
err2021-06-23
err18
errOAAI
errTang, Cheng-Chia; Andrade, Christian D. Castro; O'Meara, Maureen J.; Yoon, Sung-Hee; Sato, Tadatoshi; Brooks, Daniel J.; Bouxsein, Mary L.; Martins, Janaina da Silva; Wang, Jinhua; Gray, Nathanael S.; Misof, Barbara; Roschger, Paul; Boulin, Stephane; Klaushofer, Klaus; Velduis-Vlug, Annegreet; Vegting, Yosta; Rosen, Clifford J.; O'Connell, Daniel; Sundberg, Thomas B.; Xavier, Ramnik J.; Ung, Peter; Schlessinger, Avner; Kronenberg, Henry M.; Berdeaux, Rebecca; Foretz, Marc; Wein, Marc N.
err分享
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Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities
errCELL CHEMICAL BIOLOGY
IF7.2
err2020-10-01
err19
errOAAI
errSchroeder, Martin; Tan, Li; Wang, Jinhua; Liang, Yanke; Gray, Nathanael S.; Knapp, Stefan; Chaikuad, Apirat
err分享
err收藏
Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
errCELL CHEMICAL BIOLOGY
IF7.2
err2020-10-01
err21
errOAAI
errLiu, Yan; Ferguson, Fleur M.; Li, Lianbo; Kuljanin, Miljan; Mills, Caitlin E.; Subramanian, Kartik; Harshbarger, Wayne; Gondi, Sudershan; Wang, Jinhua; Sorger, Peter K.; Mancias, Joseph D.; Gray, Nathanael S.; Westover, Kenneth D.
err分享
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Extracellular-Regulated Protein Kinase 5-Mediated Control of p21 Expression Promotes Macrophage Proliferation Associated with Tumor Growth and Metastasis
errCANCER RESEARCH
IF16.6
err2020-08-14
err29
errOAAI
errGiurisato, Emanuele; Lonardi, Silvia; Telfer, Brian; Lussoso, Sarah; Risa-Ebri, Blanca; Zhang, Jingwei; Russo, Ilaria; Wang, Jinhua; Santucci, Annalisa; Finegan, Katherine G.; Gray, Nathanael S.; Vermi, William; Tournier, Cathy
err分享
err收藏

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