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H

Helena Mertlíková-Kaiserová

Institute of Organic Chemistry and Biochemistry
H指数:19
被引数:1,060

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荣誉奖项

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Thiophene-Linked Nucleotide Analogues as Selective and Nanomolar Inhibitors of Plasmodial 6-Oxopurine Phosphoribosyltransferases

噻吩连接的核苷类似物作为选择性纳米级抑制剂，抑制恶性疟原虫6-氧嘌呤磷酸核糖转移酶

Journal of Medicinal Chemistry
IF6.8
2026-01-010
OA
Karolína Vaňková; Jan Skácel; Dianne T. Keough; Tadeáš Kalvoda; Ondrej Gutten; Jye Travis; Marina Chavchich; Michael D. Edstein; Radek Pohl; Alexandra Dvořáková; Helena Mertlíková‐Kaiserová; Luke W. Guddat; Zlatko Janeba
Fat or flat? The impact of dipole moment vectors on non-covalent interactions between aromatic tags and macromolecules

脂肪或扁平？偶极矩矢量对芳香标记物与高分子之间非共价相互作用的影响

Inorg. Chem. Front.
IF0
2025-10-210
OAAI
Josef Holub †; Adéla Jílková †; Carina Lemke †; Lorenzo Cianni †; Petra Spiwoková; Martin Horn; Christian Breuer; Adrian Leontovyč; Jiří Brynda; Helena Mertlíková-Kaiserová; Marta Chanová; Fernanda dos Reis Rocho; Carlos A. Montanari; Nelly El-Sakkary; Conor R. Caffrey; Michael Gütschow; Drahomír Hnyk; Michael Mareš; Jindřich Fanfrlík
Zanamivir exposure in healthy rats and rats with acute lung injury

健康大鼠和急性肺损伤大鼠中扎那米韦的暴露

Annals of Medicine
IF4.3
2025-07-200
OAAI
Anežka Klouček; Jaroslava Šmardová; Michaela Sklenárová; Alexandra Dvořáková; Karel Chalupský; Pavel Ryšánek; Martina Nora Odložilíková; Aleš Bartůněk; Vít Perlík; Helena Mertlíková-Kaiserová; Pavel Michálek; Martin Šíma; Ondřej Slanař
Sulfonated Hydroxyaryl-Tetrazines with Increased pKa for Accelerated Bioorthogonal Click-to-Release Reactions in Cells

具有增加的pKa的磺化羟基芳基四嗪可加速细胞中的生物正交点击释放反应

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2024-10-310
OA
Rahm, Michal; Keppel, Patrick; Slachtova, Veronika; Dzijak, Rastislav; Dracinsky, Martin; Bellova, Simona; Reyes-Gutierrez, Paul E.; Stepanova, Sille; Raffler, Jakob; Tloustova, Eva; Mertlikova-Kaiserova, Helena; Mikula, Hannes; Vrabel, Milan
Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis
ACS INFECTIOUS DISEASES
IF3.8
2024-05-173
OAAI
Spiwokova, Petra; Horn, Martin; Fanfrlik, Jindrich; Jilkova, Adela; Fajtova, Pavla; Leontovyc, Adrian; Houstecka, Radka; Bielikova, Lucia; Brynda, Jiri; Chanova, Marta; Mertlikova-Kaiserova, Helena; Caro-Diaz, Eduardo J. E.; Almaliti, Jehad; El-Sakkary, Nelly; Gerwick, William H.; Caffrey, Conor R.; Mares, Michael
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-08-035
OAAI
Brehova, Petra; Reznickova, Eva; Skach, Krystof; Jorda, Radek; Dejmek, Milan; Vojackova, Veronika; Sala, Michal; Kovalova, Marketa; Dracinsky, Martin; Dolnikova, Alexandra; Strmen, Timotej; Kinnertova, Monika; Chalupsky, Karel; Dvorakova, Alexandra; Gucky, Tomas; Kaiserova, Helena Mertlikova; Klener, Pavel; Nencka, Radim; Krystoy, Vladimir
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-05-032
OAAI
Skacel, Jan; Djukic, Stefan; Baszczynski, Ondrej; Kalcic, Filip; Bilek, Tadeas; Chalupsky, Karel; Kozak, Jaroslav; Dvorakova, Alexandra; Tloust'ova, Eva; Kral'ova, Zuzana; Smidkova, Marketa; Voldrich, Jan; Rumlova, Michaela; Pachl, Petr; Brynda, Jiri; Vuckova, Tereza; Fabry, Milan; Snasel, Jan; Pichova, Iva; Rezacova, Pavlina; Mertlikova-Kaiserova, Helena; Janeba, Zlatko

研究方向

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Z
Zlatko Janeba
H 指数:24论文数:223被引数:2,032
M
Martin Dračínský
H 指数:35论文数:511被引数:5,399
E
Eva Tloušťová
H 指数:17论文数:92被引数:705
M
Markéta Šmídková
H 指数:11论文数:34被引数:275
A
Alexandra Dvořáková
H 指数:6论文数:24被引数:141
R
Radim Nencka
H 指数:31论文数:184被引数:3,624
M
Michal Šála
H 指数:21论文数:121被引数:1,392
V
Val J. Watts
H 指数:41论文数:183被引数:5,796
M
Michal Česnek
H 指数:13论文数:43被引数:470
D
Dejmek, Milan
H 指数:0论文数:3被引数:12