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Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition 研究基于咪唑并 [1,2-a] 吡嗪的命中化合物CTN1122的C2调节: 合成,体外抗利什曼蛋白活性,细胞毒性和酪蛋白激酶1抑制 Tisseur, Lhana; Cojean, Sandrine; Gassama, Khadidiatou; Loge, Cedric; Pagniez, Fabrice; Cave, Christian; Bernadat, Guillaume; Loiseau, Philippe M.; Bach, Stephane; Thiefaine, Jerome; Picot, Carine; Tomasoni, Christophe; Leclercq, Olivier; Baratte, Blandine; Robert, Thomas; Le Pape, Patrice; Rachidi, Najma; Bazin, Marc-Antoine; Marchand, Pascal 分享 收藏
Breaking photoswitch activation depth limit using ionising radiation stimuli adapted to clinical application Guesdon-Vennerie, Alban; Couvreur, Patrick; Ali, Fatoumia; Pouzoulet, Frederic; Roulin, Christophe; Martinez-Rovira, Immaculada; Bernadat, Guillaume; Legrand, Francois-Xavier; Bourgaux, Claudie; Mazars, Cyril Lucien; Marco, Sergio; Trepout, Sylvain; Mura, Simona; Meriaux, Sebastien; Bort, Guillaume 分享 收藏
Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana Fouotsa, Hugues; Le Pogam, Pierre; Mkounga, Pierre; Lannang, Alain Meli; Bernadat, Guillaume; Vanheuverzwijn, Jerome; Zhou, Zhiyu; Leblanc, Karine; Rharrabti, Somia; Nkengfack, Augustin Ephrem; Gallard, Jean-Francois; Fontaine, Veronique; Meyer, Franck; Poupon, Erwan; Beniddir, Mehdi A. 分享 收藏
Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenarios Leading to Its Revised and Original Structures Kouame, Tape; Bernadat, Guillaume; Turpin, Victor; Litaudon, Marc; Okpekon, Aboua Timothee; Gallard, Jean-Francois; Leblanc, Karine; Rharrabti, Somia; Champy, Pierre; Poupon, Erwan; Beniddir, Mehdi A.; Le Pogam, Pierre 分享 收藏
In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition Bazin, Marc-Antoine; Cojean, Sandrine; Pagniez, Fabrice; Bernadat, Guillaume; Cave, Christian; Ourliac-Garnier, Isabelle; Nourrisson, Marie-Renee; Morgado, Cathy; Picot, Carine; Leclercq, Olivier; Baratte, Blandine; Robert, Thomas; Spath, Gerald F.; Rachidi, Najma; Bach, Stephane; Loiseau, Philippe M.; Le Pape, Patrice; Marchand, Pascal 分享 收藏
Streamlined targeting of Amaryllidaceae alkaloids from the bulbs of Crinum scillifolium using spectrometric and taxonomically-informed scoring metabolite annotations N'Tamon, Amon Diane; Okpekon, Aboua Timothee; Bony, Nicaise F.; Bernadat, Guillaume; Gallard, Jean-Francois; Kouame, Tape; Seon-Meniel, Blandine; Leblanc, Karine; Rharrabti, Somia; Mouray, Elisabeth; Grellier, Philippe; Ake, Michele; Amin, N'Cho Christophe; Champy, Pierre; Beniddir, Mehdi A.; Le Pogam, Pierre 分享 收藏
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Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors Jaracz-Ros, Agnieszka; Bernadat, Guillaume; Cutolo, Pasquale; Gallego, Carmen; Gustavsson, Martin; Cecon, Erika; Baleux, Francoise; Kufareva, Irina; Handel, Tracy M.; Bachelerie, Francoise; Levoye, Angelique 分享 收藏
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Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Picralima nitida, a Previously Well-Investigated Species Alcover, Charlotte Fox; Bernadat, Guillaume; Kabran, Faustin A.; Le Pogam, Pierre; Leblanc, Karine; Ramos, Alexander E. Fox; Gallard, Jean-Francois; Mouray, Elisabeth; Grellier, Philippe; Poupon, Erwan; Beniddir, Mehdi A. 分享 收藏
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Design, Synthesis, and Biological Activity of New &ITN&IT-(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension Le Hiress, Morane; Akagah, Bernardin; Bernadat, Guillaume; Tu, Ly; Thuillett, Raphael; Huertas, Alice; Phan, Carole; Fadel, Elie; Simonneau, Gerald; Humbert, Marc; Jalce, Gael; Guignabert, Christophe 分享 收藏