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Shuiyu Lu

national institutes of health

H指数:26

被引数:4,328

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Deoxyradiofluorination of Phenols via a Difluoromethoxy Nucleofuge Enabled by Organic Photoredox Catalysis

通过有机光氧化还原催化的二氟甲氧基亲核试剂促进的酚类脱氧放射性氟化

ACS Central Science

IF10.4

2026-05-070

OA

Liquid Chromatography-Tandem Mass Spectrometry Methods for Rapid Measurement of the Molar Activity (Am) of Cyclotron-Produced [18F]Fluoride and Derived Radiotracers

液相色谱-串联质谱法快速测定回旋加速器生产的[18F]氟离子及其衍生的放射性示踪剂的摩尔活度（Am）

Chemistry–Methods

IF0

2026-01-180

OAAI

Expanding tracer space for positron emission tomography with high molar activity 18F-labeled α,α-difluoromethylalkanes

通过高摩尔活性的18F标记的α,α-二氟甲基烷烃扩展正电子发射断层扫描示踪剂空间

NATURE COMMUNICATIONS

IF15.7

2025-02-130

OA

Difluoromethoxide Is a Strong Leaving Group in the Photoredox Deoxyradiofluorination of 2-Phenylpyridines

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2024-09-111

PRE

On the Risk of 18F-Regioisomer Formation in the Copper-Free Radiofluorination of Aryliodonium Precursors

ORGANIC LETTERS

IF5

2023-11-271

PRE

An Empirical Quantitative Structure-Activity Relationship Equation Assists the Discovery of High-Affinity Phosphodiesterase 4D Inhibitors as Leads to PET Radioligands

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-01-066

OA

Broad Scope and High-Yield Access to Unsymmetrical Acyclic [11C]Ureas for Biomedical Imaging from [11C]Carbonyl Difluoride

从 [11C] 碳酰氟获得用于生物医学成像的不对称无环 [11C] 脲的广泛范围和高产量

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2021-06-025

OA

PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2020-05-1322

OAAI

Lu, Shuiyu; Haskali, Mohammad B.; Ruley, Kevin M.; Dreyfus, Nicolas J-F; DuBois, Susan L.; Paul, Soumen; Liow, Jeih-San; Morse, Cheryl L.; Kowalski, Aneta; Gladding, Robert L.; Gilmore, Jeremy; Mogg, Adrian J.; Morin, S. Michelle; Lindsay-Scott, Peter J.; Ruble, J. Craig; Kant, Nancy A.; Shcherbinin, Sergey; Barth, Vanessa N.; Johnson, Michael P.; Cuadrado, Maria; Jambrina, Enrique; Mannes, Andrew J.; Nuthall, Hugh N.; Zoghbi, Sami S.; Jesudason, Cynthia D.; Innis, Robert B.; Pike, Victor W.

[11C]Carbonyl Difluoride-a New and Highly Efficient [11C]Carbonyl Group Transfer Agent

[11C] 碳酰氟-一种新型高效 [11C] 羰基转移剂

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2020-03-1018

OA

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1β receptors

NUCLEAR MEDICINE AND BIOLOGY

IF3

2019-03-017

OAAI

[O-methyl-11C]N-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide ([11C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging of Brain D3 Receptors in Rodents and Monkey

IF4.6

2018-10-232

OAAI

[Carboxyl-11C]Labelling of Four High-Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography

IF3.4

2018-01-105

OAAI

Pd(0)-Mediated 11C-Carbonylation of Aryl(mesityl)iodonium Salts as a Route to [11C]Arylcarboxylic Acids and Derivatives

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2017-10-1319

PREAI

11C-Labeling of Aryl Ketones as Candidate Histamine Subtype-3 Receptor PET Radioligands through Pd(0)-Mediated 11C-Carbonylative Coupling

通过Pd(0) 介导的11c-羰基偶联标记芳基酮作为候选组胺Subtype-3受体PET放射性配体

IF4.6

2017-05-125

OAAI

Crown Ether Nucleophilic Catalysts (CENCs): Agents for Enhanced Silicon Radiofluorination

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2017-02-209

OAAI

An Investigation of (Diacetoxyiodo)arenes as Precursors for Preparing No-Carrier-Added [18F]Fluoroarenes from Cyclotron-Produced [18F]Fluoride Ion (vol 81, pg 297, 2016)

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2016-02-122

OAAI

An Investigation of (Diacetoxyiodo)arenes as Precursors for Preparing No-Carrier-Added [18F]Fluoroarenes from Cyclotron-Produced [18F]Fluoride Ion

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2015-12-1718

OAAI

[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain

NUCLEAR MEDICINE AND BIOLOGY

IF3

2015-12-0111

OAAI

The Inhibitor Ko143 Is Not Specific for ABCG2

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2015-09-01132

OAAI

11C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α1 Adrenoceptors in Brain

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2014-01-0221

OAAI