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Victor W. Pike

national institute of mental health
H指数:76
被引数:2.0万

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A Study of 3-Substituted 7-Methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ols Leading to Candidate PET Radioligands for Imaging Brain GluN2B: Design, Synthesis, and Structure–Activity Relationships

对3-取代-7-甲氧基-2,3,4,5-四氢-1H-苯并[d]氮杂卓-1-醇衍生物的研究:候选PET放射性配体用于脑GluN2B成像的设计、合成与构效关系

2026-05-060
OAAI
Subanesthetic doses of ketamine to rats and monkeys rapidly increases radioligand binding in brain to phosphodiesterase-4, an indirect marker of cAMP

亚麻醉剂量氯胺酮对大鼠和猴大脑中磷酸二酯酶-4的放射性配体结合快速增加,这是cAMP的间接标志物

2026-04-210
OAAI
Synthesis and Investigation of Substituted 1,5-Diaryl-1H-1,2,4-triazoles for the Discovery of 18F-Labeled Probes for Imaging Brain Cyclooxygenase-1

合成与探究取代的1,5-二芳基-1H-1,2,4-三唑类化合物,以发现用于脑环氧化酶-1成像的¹⁸F标记探针

2025-12-200
PRE
Evaluation of deuterated [ 18 F]JHU94620 for imaging cannabinoid type 2 receptors in rodent and monkey brain

评估重氢标记的[ <sup>18</sup> F]JHU94620在啮齿动物和猴脑中成像大麻素2型受体的研究

2025-09-180
PRE
Syntheses and preclinical evaluations of 11C-labeled radioligands for imaging brain orexin-1 and orexin-2 receptors with positron emission tomography

11C标记放射性配体的合成与临床前评价:利用正电子发射断层扫描技术成像大脑食欲素-1和食欲素-2受体

2025-08-140
OA
PET Quantification in Healthy Humans of Cyclooxygenase-2, a Potential Biomarker of Neuroinflammation

PET定量检测健康人体内的环氧化酶-2,该物质是神经炎症的潜在生物标志物。

2025-01-231
PRE
[11C]PS13 Demonstrates Pharmacologically Selective and Substantial Binding to Cyclooxygenase-1 in the Human Brain

[11C]PS13在人脑中表现出对环氧合酶-1的药理学选择性和显著结合。

2024-11-141
PRE
PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity

大鼠大脑的PET成像显示急性和慢性酒精暴露对phosphodiesterase-4B的相反影响,cAMP活性的间接生物标志物

2024-09-162
OAAI