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H

Hirotatsu Kojima

University of Tokyo
H指数:46
被引数:1.2万

个人简介

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工作经历

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荣誉奖项

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Development of Keap1-Nrf2 Protein–Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, and its Anti-Inflammatory Effects

基于萘-2-乙酰胺骨架开发激活细胞内Nrf2的Keap1-Nrf2蛋白质-蛋白质相互作用抑制剂及其抗炎作用

ChemMedChem
IF3.4
2025-09-030
OAAI
Daisuke Yasuda; Kai Toyoshima; Koujin Kojima; Hanako Ishida; Kazuma Kaitoh; Riyo Imamura; Kayoko Kanamitsu; Hirotatsu Kojima; Megumi Funakoshi-Tago; Masanori Osawa; Tomoyuki Ohe; Tomoya Hirano
Alvespimycin is identified as a novel therapeutic agent for diabetic kidney disease by chemical screening targeting extracellular vesicles

Alvespimycin通过靶向细胞外囊泡的化学筛选被鉴定为糖尿病肾病的新型治疗剂。

SCIENTIFIC REPORTS
IF3.9
2025-04-250
OA
Fujimoto, Daisuke; Umemoto, Shuro; Mizumoto, Teruhiko; Kanki, Tomoko; Hata, Yusuke; Nishiguchi, Yoshihiko; Date, Ryosuke; Zhang, Jingxuan; Kakizoe, Yutaka; Izumi, Yuichiro; Adachi, Masataka; Kojima, Hirotatsu; Yokoi, Hideki; Mukoyama, Masashi; Kuwabara, Takashige
Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation
SCIENTIFIC REPORTS
IF3.9
2023-09-304
OAAI
Echizen, Honami; Hanaoka, Kenjiro; Shimamoto, Kazuhito; Hibi, Ryota; Toma-Fukai, Sachiko; Ohno, Hisashi; Sasaki, Eita; Komatsu, Toru; Ueno, Tasuku; Tsuchiya, Yukihiro; Watanabe, Yasuo; Otsuka, Takao; Saito, Hiroaki; Nagatoishi, Satoru; Tsumoto, Kouhei; Kojima, Hirotatsu; Okabe, Takayoshi; Shimizu, Toshiyuki; Urano, Yasuteru
Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Compound Library
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2022-11-158
OAAI
Nurkanto, Arif; Imamura, Riyo; Rahmawati, Yulia; Prabandari, Erwahyuni Endang; Waluyo, Danang; Annoura, Takeshi; Yamamoto, Kazuki; Sekijima, Masakazu; Nishimura, Yuki; Okabe, Takayoshi; Shiba, Tomoo; Shibata, Norio; Kojima, Hirotatsu; Duffy, James; Nozaki, Tomoyoshi
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2020-05-0117
OAAI
Koiwai, Kotaro; Inaba, Kazue; Morohashi, Kana; Enya, Sora; Arai, Reina; Kojima, Hirotatsu; Okabe, Takayoshi; Fujikawa, Yuuta; Inoue, Hideshi; Yoshino, Ryunosuke; Hirokawa, Takatsugu; Kato, Koichiro; Fukuzawa, Kaori; Shimada-Niwa, Yuko; Nakamura, Akira; Yumoto, Fumiaki; Senda, Toshiya; Niwa, Ryusuke

研究方向

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T
Tetsuo Nagano
H 指数:104论文数:703被引数:3.9万
T
Takayoshi Okabe
H 指数:32论文数:147被引数:3,748
Y
Yasuteru Urano
H 指数:94论文数:526被引数:3.5万
K
Kenjiro Hanaoka
H 指数:62论文数:234被引数:1.3万
T
Takuya Terai
H 指数:47论文数:138被引数:9,522
K
Kazuya Kikuchi
H 指数:0论文数:4被引数:0
T
Tasuku Ueno
H 指数:46论文数:206被引数:8,777
T
Toru Komatsu
H 指数:49论文数:204被引数:8,018
Y
Yasunobu Hirata
H 指数:66论文数:558被引数:1.5万
Y
Yuuta Fujikawa
H 指数:13论文数:37被引数:1,145