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Synthesis of 1,2,3-Triazole-Methyl-Menadione Derivatives: Evaluation of Electrochemical and Antiparasitic Properties against two Blood-Dwelling Parasites Dupouy, Baptiste; Karpstein, Tanja; Haberli, Cecile; Cal, Monica; Rottmann, Matthias; Maser, Pascal; Keiser, Jennifer; Cichocki, B.; Elhabiri, Mourad; Davioud-Charvet, Elisabeth 分享 收藏
Click Coupling of Flavylium Dyes with Plasmodione Analogues: Towards New Redox-Sensitive Pro-Fluorophores 黄色素染料与疟原虫类似物的点击偶联: 走向新的氧化还原敏感的前荧光团 Dupouy, Baptiste; Cotos, Leandro; Binder, Annika; Slavikova, Lucie; Rottmann, Matthias; Maser, Pascal; Jacquemin, Denis; Ganter, Markus; Davioud-Charvet, Elisabeth; Elhabiri, Mourad 分享 收藏
Drug Interaction Studies of Cabamiquine:Ganaplacide Combination against Hepatic Plasmodium berghei Gal, Isabella Ramella; Demarta-Gatsi, Claudia; Fontinha, Diana; Arez, Francisca; Wicha, Sebastian G.; Rottmann, Matthias; Nunes-Cabaco, Helena; Blais, Johanne; Jain, Jay Prakash; Lakshminarayana, Suresh B.; Brito, Catarina; Prudencio, Miguel; Alves, Paula M.; Spangenberg, Thomas 分享 收藏
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Tambjamines as Fast-Acting Multistage Antimalarials Kumar, Amrendra; Li, Yuexin; Dodean, Rozalia A.; Roth, Alison; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Lee, Patricia J.; Pybus, Brandon S.; Martin, Monica; Pannone, Kristina; Dinh, Hieu T.; Blount, Cameron; Chetree, Ravi; Deluca, Jesse; Evans, Martin; Nadeau, Robert; Vuong, Chau; Leed, Susan; Black, Chad; Sousa, Jason; Nolan, Christina; Ceja, Frida G.; Rasmussen, Stephanie A.; Tumwebaze, Patrick K.; Rosenthal, Philip J.; Cooper, Roland A.; Rottmann, Matthias; Orjuela-Sanchez, Pamela; Meister, Stephan; Winzeler, Elizabeth A.; Delves, Michael J.; Matthews, Holly; Baum, Jake; Kirby, Robert W.; Burrows, Jeremy N.; Duffy, James; Peyton, David H.; Reynolds, Kevin A.; Kelly, Jane X.; Kancharla, Papireddy 分享 收藏
Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies Cesar-Rodo, Elena; Dupouy, Baptiste; Haberli, Cecile; Strub, Jean-Marc; Williams, David L.; Maser, Pascal; Rottmann, Matthias; Keiser, Jennifer; Lanfranchi, Don Antoine; Davioud-Charvet, Elisabeth 分享 收藏
Targeting the Plasmodium falciparum IspE Enzyme Diamanti, Eleonora; Steinbach, Annina M.; de Carvalho, Lais P.; Ropponen, Henni-Karoliina; Lacour, Antoine; Hamid, Rawia; Eisa, Sidra; Bravo, Patricia; Bousis, Spyridon; Illarionov, Boris; Fischer, Markus; Hamed, Mostafa M.; Bach, Nina C.; Rottmann, Matthias; Held, Jana; Witschel, Matthias; Sieber, Stephan A.; Hirsch, Anna K. H. 分享 收藏
3-Benzylmenadiones and their Heteroaromatic Analogues Target the Apicoplast of Apicomplexa Parasites: Synthesis and Bioimaging Studies Dupouy, Baptiste; Donzel, Maxime; Roignant, Matthieu; Charital, Sarah; Keumoe, Rodrigue; Yamaryo-Botte, Yoshiki; Feckler, Alexander; Bundschuh, Mirco; Bordat, Yann; Rottmann, Matthias; Maser, Pascal; Botte, Cyrille Y.; Blandin, Stephanie A.; Besteiro, Sebastien; Davioud-Charvet, Elisabeth 分享 收藏
Targeting Plasmodium falciparum IspD in the Methyl-D-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity Willocx, Daan; Bizzarri, Lorenzo; Alhayek, Alaa; Kannan, Deepika; Bravo, Patricia; Illarionov, Boris; Rox, Katharina; Lohse, Jonas; Fischer, Markus; Kany, Andreas M.; Hahne, Hannes; Rottmann, Matthias; Witschel, Matthias; Odom John, Audrey; Hamed, Mostafa M.; Diamanti, Eleonora; Hirsch, Anna K. H. 分享 收藏
Genetic validation of PfFKBP35 as an antimalarial drug target Thommen, Basil T.; Dziekan, Jerzy M.; Achcar, Fiona; Tjia, Seth; Passecker, Armin; Buczak, Katarzyna; Gumpp, Christin; Schmidt, Alexander; Rottmann, Matthias; Gruering, Christof; Marti, Matthias; Brancucci, Nicolas M. B. 分享 收藏
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Antimalarial Agents Derived from Metal-Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle Colina-Vegas, Legna; Silva, Mariana da Cruz B.; de Souza Pereira, Caroline; Barros, Ariane Isis; Nobrega, Joaquim Araujo; Navarro, Maribel; Rottmann, Matthias; D'Alessandro, Sarah; Basilico, Nicoletta; Batista, Alzir Azevedo; Moreira, Diogo R. M. 分享 收藏
New In Vitro Interaction-Parasite Reduction Ratio Assay for Early Derisk in Clinical Development of Antimalarial Combinations Wicha, Sebastian G.; Walz, Annabelle; Cherkaoui-Rbati, Mohammed H.; Bundgaard, Nils; Kuritz, Karsten; Gumpp, Christin; Gobeau, Nathalie; Mohrle, Jorg; Rottmann, Matthias; Demarta-Gatsi, Claudia 分享 收藏
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 有效，有效，口服可用的抗疟血浆蛋白酶X抑制剂的发现和表征以及UCB7362的临床前安全性评估 Lowe, Martin A. .; Cardenas, Alvaro; Valentin, Jean-Pierre; Zhu, Zhaoning; Abendroth, Jan; Castro, Jose L.; Class, Reiner; Delaunois, Annie; Fleurance, Renaud; Gerets, Helga; Gryshkova, Vitalina; King, Lloyd; Lorimer, Donald D.; MacCoss, Malcolm; Rowley, Julian H.; Rosseels, Marie-Luce; Royer, Leandro; Taylor, Richard D.; Wong, Melanie; Zaccheo, Oliver; Chavan, Vishal P.; Ghule, Gokul A. .; Tapkir, Bapusaheb K.; Burrows, Jeremy N.; Duffey, Maelle; Rottmann, Matthias; Wittlin, Sergio; Angulo-Barturen, Inigo; Belen Jimenez-Diaz, Maria; Striepen, Josefine; Fairhurst, Kate J.; Yeo, Tomas; Fidock, David A. .; Cowman, Alan F.; Favuzza, Paola; Crespo-Fernandez, Benigno; Javier Gamo, Francisco; Goldberg, Daniel E.; Soldati-Favre, Dominique; Laleu, Benoit; de Haro, Teresa 分享 收藏
Parasite Viability as a Measure of In Vivo Drug Activity in Preclinical and Early Clinical Antimalarial Drug Assessment Radohery, Georges F. R.; Walz, Annabelle; Gumpp, Christin; Cherkaoui-Rbati, Mohammed H.; Gobeau, Nathalie; Gower, Jeremy; Davenport, Miles P.; Rottmann, Matthias; McCarthy, James S.; Mohrle, Jorg J.; Rebelo, Maria; Demarta-Gatsi, Claudia; Khoury, David S. 分享 收藏
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Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor Rottmann, Matthias; Jonat, Brian; Gumpp, Christin; Dhingra, Satish K.; Giddins, Marla J.; Yin, Xiaoyan; Badolo, Lassina; Greco, Beatrice; Fidock, David A.; Oeuvray, Claude; Spangenberg, Thomas 分享 收藏
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