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J

Joseph Bradley

washington university
H指数:13
被引数:1,212

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GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy

脑脊液阿尔茨海默病生物标志物的GWAS荟萃分析揭示了调控脂质、脑容量和自噬的基因位点

Nature Communications
IF15.7
2026-04-210
OAAI
Jigyasha Timsina; Chenyang Jiang; Daniel L. McCartney; Feifei Tao; Maria Carolina Dalmasso; Jenna Najar; Federica Anastasi; Olena Ohlei; Raquel Puerta Fuentes; Chenyu Yang; Joseph Bradley; Daniel Western; Muhammad Ali; Ciyang Wang; Chengran Yang; Ying Wu; Menghan Liu; John Budde; Julie Williams; Rebecca Mahoney; Atahualpa Castillo Morales; Timothy J. Hohman; Logan Dumitrescu; Ting-Chen Wang; Niccolo’ Tesi; Silke Kern; Margda Waern; Ingmar Skoog; Argonde van Harten; Yolande A. L. Pijnenburg; Wiesje M. van der Flier; Pascual Sánchez-Juan; Eloy Rodriguez-Rodriguez; Luca Kleineidam; Oliver Peters; Anja Schneider; Fahri Küçükali; Céline Bellenguez; Benjamin Grenier-Boley; Sami Heikkinen; Itziar de Rojas; Dan Rujescu; Norbert Scherbaum; Lucrezia Hausner; Emrah Düzel; Timo Grimmer; Jens Wiltfang; Rik Vandenberghe; Sebastiaan Engelborghs; Stefanie Heilmann-Heimbach; Matthias Schmid; Thomas Tegos; Nikolaos Scarmeas; Oriol Dols-Icardo; Fermin Moreno; Jordi Pérez-Tur; María J. Bullido; Raquel Sánchez-Valle; Victoria Álvarez; Pablo García-González; Pablo Mir; Luis M. Real; Gerard Piñol-Ripoll; Jose María García-Alberca; Harro Seelaar; Inez Ramakers; Janne Papma; Marc Hulsman; Christoph Laske; Stefan Teipel; Josef Priller; Robert Perneczky; Katharina Buerger; Markus M. Nöthen; Piotr Lewczuk; Johannes Kornhuber; Harald Hampel; Ina Giegling; Oliver Goldhardt; Janine Diehl-Schmid; Victor Andrade; Michael MT. Heneka; Lutz Frölich; Jonathan Vogelgsang; Caroline Graff; Hakan Thonberg; Abbe Ullgren; Goran Papenberg; Jean-François Deleuze; Carole Dufouil; Michael Wagner; Frank Jessen; Henne Holstege; Cornelia van Duijn; Thibaud Lebouvier; Olivier Hannon; Ville Leinonen; Hilkka Soininen; Sanna-Kaisa Herukka; Vilmantas Giedraitis; Malin Löwenmark; Lena Kilander; Patricia Genius; Blanca Rodríguez; Emma S. Luckett; Arcadi Navarro; Amanda Cano; Marta Marquié; Kaj Blennow; Henrik Zetterberg; Alberto Lleo; Mercè Boada; Agustin Ruiz; Virginia Man-Yee Lee; Vivianna M. Van Deerlin; Yuetiva Deming; Sterling C. Johnson; Corinne D. Engelman; Pau Pastor; Ignacio Alvarez; Elaine R. Peskind; Amanda J. Heslegrave; Andrew J. Saykin; Kwangsik Nho; Suzanne E. Schindler; John C. Morris; David M. Holtzman; Eric McDade; Alan E. Renton; Alison Goate; Laura Ibanez; Matthias Riemenschneider; Marilyn S. Albert; Simon M. Laws; Tenielle Porter; Eleanor K. O’Brien; Leslie M. Shaw; Betty M. Tijms; Martin Ingelsson; Pieter Jelle Visser; Mikko Hiltunen; Kristel Sleegers; Craig W. Ritchie; Rebecca Sims; Michael Belloy; Jean-Charles Lambert; Natalia Vilor-Tejedor; Maria Victoria Fernández; Qingqin S. Li; Michael W. Nagle; Riccardo E. Marioni; Alfredo Ramirez; Lars Bertram; Sven J. van der Lee; Carlos Cruchaga
RBFOX1 association with age at onset of Alzheimer's disease

RBFOX1与阿尔茨海默病发病年龄的关联

alzheimer's & dementia
IF0
2026-02-220
OAAI
Laura Xicota; Rong Cheng; Stacy L. Andersen; Joseph M. Zmuda; Mary Wojczynski; Mary F. Feitosa; Joseph Bradley; Carlos Cruchaga; Alex G. Contreras; Timothy J. Hohman; Dolly Reyes-Dumeyer; Badri V. Vardarajan; Stephanie Cosentino; Richard Mayeux; Joseph H. Lee; Sandra Barral; the Long-Life Family Study (LLFS), Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA), and The National Institute on Aging Alzheimer's Disease Family Based Study (NIA-LOAD FBS)
The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology
ALZHEIMERS & DEMENTIA
IF11.1
2023-06-301
OA
Ray, Nicholas R.; Ayodele, Temitope; Jean-Francois, Melissa; Baez, Penelope; Fernandez, Victoria; Bradley, Joseph; Crane, Paul K.; Dalgard, Clifton L.; Kuzma, Amanda; Nicaretta, Heather; Sims, Rebecca; Williams, Julie; Cuccaro, Michael L.; Pericak-Vance, Margaret A.; Mayeux, Richard; Wang, Li-San; Schellenberg, Gerard D.; Cruchaga, Carlos; Beecham, Gary W.; Reitz, Christiane
Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred
ALZHEIMERS & DEMENTIA
IF11.1
2023-03-237
PRE
Cochran, Jesse Nicholas; Acosta-Uribe, Juliana; Esposito, Bianca T.; Madrigal, Lucia; Aguillon, David; Giraldo, Margarita M.; Taylor, Jared W.; Bradley, Joseph; Fulton-Howard, Brian; Andrews, Shea J.; Acosta-Baena, Natalia; Alzate, Diana; Garcia, Gloria P.; Piedrahita, Francisco; Lopez, Hugo E.; Anderson, Ashlyn G.; Rodriguez-Nunez, Ivan; Roberts, Kevin; Absher, Devin; Myers, Richard M.; Beecham, Gary W.; Reitz, Christiane; Rizzardi, Lindsay F.; Fernandez, Maria Victoria; Goate, Alison M.; Cruchaga, Carlos; Renton, Alan E.; Lopera, Francisco; Kosik, Kenneth S.
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains
ALZHEIMERS & DEMENTIA
IF11.1
2022-10-1714
OA
Novotny, Brenna C.; Fernandez, Maria Victoria; Wang, Ciyang; Budde, John P.; Bergmann, Kristy; Eteleeb, Abdallah M.; Bradley, Joseph; Webster, Carol; Ebl, Curtis; Norton, Joanne; Gentsch, Jen; Dube, Umber; Wang, Fengxian; Morris, John C.; Bateman, Randall J.; Perrin, Richard J.; McDade, Eric; Xiong, Chengjie; Chhatwal, Jasmeer; Goate, Alison; Farlow, Martin; Schofield, Peter; Chui, Helena; Karch, Celeste M.; Cruchaga, Carlos; Benitez, Bruno A.; Harari, Oscar
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke
BRAIN
IF11.7
2022-02-2514
OA
Ibanez, Laura; Heitsch, Laura; Carrera, Caty; Farias, Fabiana H. G.; Del Aguila, Jorge L.; Dhar, Rajat; Budde, John; Bergmann, Kristy; Bradley, Joseph; Harari, Oscar; Phuah, Chia Ling; Lemmens, Robin; Viana Oliveira Souza, Alessandro A.; Moniche, Francisco; Cabezas-Juan, Antonio; Arenillas, Juan Francisco; Krupinksi, Jerzy; Cullell, Natalia; Torres-Aguila, Nuria; Muino, Elena; Carcel-Marquez, Jara; Marti-Fabregas, Joan; Delgado-Mederos, Raquel; Marin-Bueno, Rebeca; Hornick, Alejandro; Vives-Bauza, Cristofol; Navarro, Rosa Diaz; Tur, Silvia; Jimenez, Carmen; Obach, Victor; Segura, Tomas; Serrano-Heras, Gemma; Chung, Jong Won; Roquer, Jaume; Soriano-Tarraga, Carol; Giralt-Steinhauer, Eva; Mola-Caminal, Marina; Pera, Joanna; Lapicka-Bodzioch, Katarzyna; Derbisz, Justyna; Davalos, Antoni; Lopez-Cancio, Elena; Munoz, Lucia; Tatlisumak, Turgut; Molina, Carlos; Ribo, Marc; Bustamante, Alejandro; Sobrino, Tomas; Castillo-Sanchez, Jose; Campos, Francisco; Rodriguez-Castro, Emilio; Arias-Rivas, Susana; Rodriguez-Yanez, Manuel; Herbosa, Christina; Ford, Andria L.; Gutierrez-Romero, Alonso; Uribe-Pacheco, Rodrigo; Arauz, Antonio; Lopes-Cendes, Iscia; Lowenkopf, Theodore; Barboza, Miguel A.; Amini, Hajar; Stamova, Boryana; Ander, Bradley P.; Sharp, Frank R.; Kim, Gyeong Moon; Bang, Oh Young; Jimenez-Conde, Jordi; Slowik, Agnieszka; Stribian, Daniel; Tsai, Ellen A.; Burkly, Linda C.; Montaner, Joan; Fernandez-Cadenas, Israel; Lee, Jin Moo; Cruchaga, Carlos
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion
ACTA NEUROPATHOLOGICA
IF9.3
2019-08-2749
OAAI
Li, Zeran; Farias, Fabiana H. G.; Dube, Umber; Del-Aguila, Jorge L.; Mihindukulasuriya, Kathie A.; Fernandez, Maria Victoria; Ibanez, Laura; Budde, John P.; Wang, Fengxian; Lake, Allison M.; Deming, Yuetiva; Perez, James; Yang, Chengran; Bahena, Jorge A.; Qin, Wei; Bradley, Joseph L.; Davenport, Richard; Bergmann, Kristy; Morris, John C.; Perrin, Richard J.; Benitez, Bruno A.; Dougherty, Joseph D.; Harari, Oscar; Cruchaga, Carlos
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2019-08-14177
OAAI
Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jorge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura; Cruchaga, Carlos
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

人脑中孟德尔和散发性AD的单核RNA测序研究

ALZHEIMERS RESEARCH & THERAPY
IF7.6
2019-08-09127
OAAI
Del-Aguila, Jorge L.; Li, Zeran; Dube, Umber; Mihindukulasuriya, Kathie A.; Budde, John P.; Fernandez, Maria Victoria; Ibanez, Laura; Bradley, Joseph; Wang, Fengxian; Bergmann, Kristy; Davenport, Richard; Morris, John C.; Holtzman, David M.; Perrin, Richard J.; Benitez, Bruno A.; Dougherty, Joseph; Cruchaga, Carlos; Harari, Oscar
Overlap in the Genetic Architecture of Stroke Risk, Early Neurological Changes, and Cardiovascular Risk Factors

中风风险，早期神经系统变化和心血管危险因素的遗传结构重叠

STROKE
IF8.9
2019-06-0116
OAAI
Ibanez, Laura; Heitsch, Laura; Dube, Umber; Farias, Fabiana H. G.; Budde, John; Bergmann, Kristy; Davenport, Rich; Bradley, Joseph; Carrera, Caty; Kinnunen, Janne; Sallinen, Hanne; Strbian, Daniel; Slowik, Agnieszka; Fernandez-Cadenas, Israel; Montaner, Joan; Lee, Jin-Moo; Cruchaga, Carlos

研究方向

暂未获取到该数据
C
Carlos Cruchaga
H 指数:99论文数:885被引数:6.3万
J
John Budde
H 指数:39论文数:170被引数:7,793
L
Laura Ibáñez
H 指数:35论文数:174被引数:9,480
U
Umber Dube
H 指数:21论文数:57被引数:2,293
M
María Victoria Fernández
H 指数:36论文数:199被引数:5,720
K
Kristy Bergmann
H 指数:13论文数:43被引数:757
J
Jorge L. Del‐Aguila
H 指数:28论文数:64被引数:4,886
O
Oscar Harari
H 指数:39论文数:178被引数:9,252
Z
Zeran Li
H 指数:15论文数:41被引数:2,119
J
John C. Morris
H 指数:212论文数:2,376被引数:23.4万