Alejandro A. Pezzulo - Publications, H-index & Citations

Alejandro A. Pezzulo

university of alabama birmingham

32H指数

126论文数

5.5K被引数

收录论文 48

发表时间

Acute malaria dysregulates specialized lymph node macrophages to suppress vaccine-elicited protection against the Ebola virus 急性疟疾可导致特殊淋巴结巨噬细胞功能失调，从而抑制针对埃博拉病毒的疫苗诱导保护作用。

mBio

IF4.7

2025-12-01

PREAI

Elliff, Jonah; Grady, Lindsey; O'Donnell, Kyle L.; Messingham, Caitlin; Rogers, Kai J.; Akther, Jobaida; Thurman, Andrew; Vijay, Rahul; Pezzulo, Alejandro; Randall, Troy; Marzi, Andrea; Butler, Noah S.; Maury, Wendy

Porcine airway tissue explant culture at a hydrogel-air interface to model submucosal glands in cystic fibrosis progression and therapy 猪气道组织离体培养在凝胶-空气界面以模拟囊性纤维化进展和疗法中的黏膜下腺体

SCIENCE ADVANCES

IF12.5

2025-11-19

PREAI

Bierstedt, Kaleb C.; Lin, Meng-Hsuan; Yu, Wenjie; Cooney, Ashley L.; Goodell, Brian J.; Gong, Huiyu; Pezzulo, Alejandro A.; Sinn, Patrick L.; Xie, Yuliang

Theratyping as a tool to guide clinical decision-making in patients with suspected cystic fibrosis and variants currently ineligible for CFTR modulator therapy 表型分型作为一种指导疑似囊性纤维化且目前不符合CFTR调节剂治疗条件的患者的临床决策工具

RESPIRATORY MEDICINE

IF3.1

2025-11-01

OAAI

Gannon, Ryan M.; Wright, Brittany A.; Bettis, Brandon A.; Teresi, Mary E.; Fischer, Anthony J.; Weiner, Rebecca L.; Pena, Tahuanty; Hornick, Douglas B.; Thornell, Ian M.; Rehman, Tayyab; Pezzulo, Alejandro A.

IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo via eicosanoid signalling IL-13降低对气道上皮SARS-CoV-2感染的易感性，但在体内通过花生四烯酸信号通路增加疾病严重程度。

eBioMedicine

IF10.8

2025-09-15

PREAI

Shreya Ghimire; Biyun Xue; Kun Li; Ryan M. Gannon; Christine L. Wohlford-Lenane; Andrew L. Thurman; Huiyu Gong; Grace C. Necker; Jian Zheng; David K. Meyerholz; Stanley Perlman; Paul B. McCray; Alejandro A. Pezzulo

Manual segmentation of opacities and consolidations on CT of long COVID patients from multiple annotators 多 annotators 对长 COVID 患者CT上的渗出物和实变进行手动分割

SCIENTIFIC DATA

IF6.9

2025-03-07

OAAI

Carmo, Diedre S.; Pezzulo, Alejandro A.; Villacreses, Raul A.; Eisenbeisz, McKenna L.; Anderson, Rachel L.; Van Dorin, Sarah E.; Lotufo, Roberto A.; Gerard, Sarah E.; Reinhardt, Joseph M.; Comellas, Alejandro P.

Complement is primarily activated in the lung in a mouse model of severe COVID-19 在严重COVID-19小鼠模型中，补体主要在肺部被激活。

ISCIENCE

IF4.1

2025-03-01

OAAI

Szachowicz, Peter J.; Wohlford-Lenane, Christine; Donelson, Cobey J.; Ghimire, Shreya; Thurman, Andrew; Xue, Biyun; Boly, Timothy J.; Verma, Abhishek; Masinovic, Leila; Bermick, Jennifer R.; Rehman, Tayyab; Perlman, Stanley; Meyerholz, David K.; Pezzulo, Alejandro A.; Zhang, Yuzhou; Smith, Richard J. H.; McCray, Paul B.

AIR TRAPPING AND GROUND GLASS OPACITIES IN POST-COVID: USEFUL MARKERS OF DISEASE OR UNCORRELATED COINCIDENCE?

CHEST

IF8.6

2024-10-01

PREAI

Stalker, Grant; Tudas, Rosarie; Gerard, Sarah; Villacreses, Raul A.; Guo, Junfeng; Fortis, Spyridon; Pezzulo, Alejandro; Comellas, Alejandro P.

IL-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-09-10

OAAI

Ibarra, Guillermo S. Romano; Lei, Lei; Yu, Wenjie; Thurman, Andrew L.; Gansemer, Nicholas D.; Meyerholz, David K.; Pezzulo, Alejandro A.; McCray, Paul B.; Thornell, Ian M.; Stoltz, David A.

Epithelial responses to CFTR modulators are improved by inflammatory cytokines and impaired by antiinflammatory drugs

JCI INSIGHT

IF6.1

2024-06-18

OAAI

Rehman, Tayyab; Pezzulo, Alejandro A.; Thurman, Andrew L.; Zemans, Rachel L.; Welsh, Michael J.

Eosinophil expression of triggering receptor expressed on myeloid cells 1 (TREM-1) restricts type 2 lung inflammation

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2024-03-28

PREAI

Bowen, Jayden L.; Keck, Kathy; Baruah, Sankar; Nguyen, Kathy H.; Thurman, Andrew L.; Pezzulo, Alejandro A.; Klesney-Tait, Julia

Increased ENaC-mediated liquid absorption across vitamin-D deficient human airway epithelia

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2024-02-01

PREAI

Stapleton, Emma M.; Thurman, Andrew L.; Pezzulo, Alejandro A.; Comellas, Alejandro P.; Thornell, Ian M.

Interleukin 13-Induced Inflammation Increases DPP4 Abundance but Does Not Enhance Middle East Respiratory Syndrome Coronavirus Replication in Airway Epithelia

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2023-09-12

OAAI

Li, Kun; Bartlett, Jennifer A.; Wohlford-Lenane, Christine L.; Xue, Biyun; Thurman, Andrew L.; Gallagher, Thomas M.; Pezzulo, Alejandro A.; Mccray, Paul B.

DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation DNA去甲基化在胸腺调节性T细胞分化过程中微调IL-2的产生

EMBO REPORTS

IF6.2

2023-03-07

OAAI

Teghanemt, Athmane; Misel-Wuchter, Kara; Heath, Jace; Thurman, Andrew; Pulipati, Priyanjali; Dixit, Garima; Geesala, Ramasatya; Meyerholz, David K.; Maretzky, Thorsten; Pezzulo, Alejandro; Issuree, Priya D.

FXYD3 facilitates Na 1 and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2022-10-01

OAAI

Portillo, Camilo Cano; Villacreses, Raul; Thurman, Andrew L.; Pezzulo, Alejandro A.; Zabner, Joseph; Thornell, Ian M.

WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2022-10-01

OAAI

Rehman, Tayyab; Karp, Philip H.; Thurman, Andrew L.; Mather, Steven E.; Jain, Akansha; Cooney, Ashley L.; Sinn, Patrick L.; Pezzulo, Alejandro A.; Duffey, Michael E.; Welsh, Michael J.

Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection

RADIOLOGY

IF15.2

2022-07-01

OAAI

Cho, Josalyn L.; Villacreses, Raul; Nagpal, Prashant; Guo, Junfeng; Pezzulo, Alejandro A.; Thurman, Andrew L.; Hamzeh, Nabeel Y.; Blount, Robert J.; Fortis, Spyridon; Hoffman, Eric A.; Zabner, Joseph; Comellas, Alejandro P.

A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2022-06-01

OAAI

Thurman, Andrew L.; Li, Xiaopeng; Villacreses, Raul; Yu, Wenjie; Gong, Huiyu; Mather, Steven E.; Romano-Ibarra, Guillermo S.; Meyerholz, David K.; Stoltz, David A.; Welsh, Michael J.; Thornell, Ian M.; Zabner, Joseph; Pezzulo, Alejandro A.

FXYD3 increases Na+ transport across human airway epithelia

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Portillo, Camilo Cano; Villacreses, Raul; Thurman, Andrew; Pezzulo, Alejandro; Zabner, Joseph; Thornell, Ian M.

Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

OAAI

Zheng, Jian; Wong, Lok-Yin Roy; Wilhelmsen, Kevin; Li, Kun; Ortiz, Miguel E.; Schnicker, Nicholas J.; Thurman, Andrew; Pezzulo, Alejandro A.; Szachowicz, Peter J.; Li, Pengfei; Pan, Ruangang; Klumpp, Klaus; Aswad, Fred; Rebo, Justin; Narumiya, Shuh; Murakami, Makoto; Zuniga, Sonia; Sola, Isabel; Enjuanes, Luis; Meyerholz, David K.; Fortney, Kristen; McCray, Paul B.; Perlman, Stanley

Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs 野生型和囊性纤维化猪粘膜下腺体的细胞和分子结构

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-01-19

OAAI

Yu, Wenjie; Moninger, Thomas O.; Thurman, Andrew L.; Xie, Yuliang; Jain, Akansha; Zarei, Keyan; Powers, Linda S.; Pezzulo, Alejandro A.; Stoltz, David A.; Welsh, Michael J.

研究方向