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Paul B. McCray

university of iowa

95H指数
366论文数
3.4W被引数
收录论文 182
发表时间
CFTR gene delivery to human airway epithelia using parainfluenza virus 5 amplifying virus-like particles利用副流感病毒5扩增类病毒颗粒将CFTR基因递送至人呼吸道上皮细胞
err2026-06-08
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errMark A. Phillips; Lei Lei; Katarina Kulhankova; María Cristina Gingerich; Laura Marquez Loza; Amber Vu; Biao He; Ian M. Thornell; Paul B. McCray
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IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo via eicosanoid signallingIL-13降低对气道上皮SARS-CoV-2感染的易感性,但在体内通过花生四烯酸信号通路增加疾病严重程度。
err2025-09-15
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PREAI
errShreya Ghimire; Biyun Xue; Kun Li; Ryan M. Gannon; Christine L. Wohlford-Lenane; Andrew L. Thurman; Huiyu Gong; Grace C. Necker; Jian Zheng; David K. Meyerholz; Stanley Perlman; Paul B. McCray; Alejandro A. Pezzulo
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Complement is primarily activated in the lung in a mouse model of severe COVID-19在严重COVID-19小鼠模型中,补体主要在肺部被激活。
err2025-03-01
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errOAAI
errSzachowicz, Peter J.; Wohlford-Lenane, Christine; Donelson, Cobey J.; Ghimire, Shreya; Thurman, Andrew; Xue, Biyun; Boly, Timothy J.; Verma, Abhishek; Masinovic, Leila; Bermick, Jennifer R.; Rehman, Tayyab; Perlman, Stanley; Meyerholz, David K.; Pezzulo, Alejandro A.; Zhang, Yuzhou; Smith, Richard J. H.; McCray, Paul B.
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CF airway epithelia display exaggerated host defense responses and prolonged cilia loss during RSV infectionCF气道上皮细胞在呼吸道合胞病毒感染期间表现出过度宿主防御反应和持续纤毛丢失。
err2025-02-15
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PREAI
errJennifer A. Bartlett; Eric D. Huntemann; Sateesh Krishnamurthy; Stacey M. Hartwig; Alvin Pewa; Andrew L. Thurman; Michael S. Chimenti; Eric B. Taylor; Steven M. Varga; Paul B. McCray Jr
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Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells
err2024-09-24
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errKulhankova, Katarina; Cheng, Anna X.; Traore, Soumba; Auger, Maud; Pelletier, Mia; Hervault, Maxime; Wells, Kevin D.; Green, Jonathan A.; Byrne, Addison; Nelson, Benjamin; Sponchiado, Mariana; Boosani, Chandra; Heffner, Caleb S.; Snow, Kathy J.; Murray, Stephen A.; Villacreses, Raul A.; Rector, Michael, V; Gansemer, Nicholas D.; Stoltz, David A.; Allamargot, Chantal; Couture, Frederic; Hemez, Colin; Hallee, Stephanie; Barbeau, Xavier; Harvey, Mario; Lauvaux, Coraline; Gaillet, Bruno; Newby, Gregory A.; Liu, David R.; McCray Jr, Paul B.; Guay, David
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IL-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption
err2024-09-10
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errIbarra, Guillermo S. Romano; Lei, Lei; Yu, Wenjie; Thurman, Andrew L.; Gansemer, Nicholas D.; Meyerholz, David K.; Pezzulo, Alejandro A.; McCray, Paul B.; Thornell, Ian M.; Stoltz, David A.
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High ionic strength vector formulations enhance gene transfer to airway epithelia
err2024-07-30
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errOAAI
errCooney, Ashley L.; Loza, Laura Marquez; Najdawi, Kenan; Brommel, Christian M.; McCray Jr, Paul B.; Sinn, Patrick L.
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Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells
err2024-07-10
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errSousa, Alexander A.; Hemez, Colin; Lei, Lei; Traore, Soumba; Kulhankova, Katarina; Newby, Gregory A.; Doman, Jordan L.; Oye, Keyede; Pandey, Smriti; Karp, Philip H.; McCray Jr, Paul B.; Liu, David R.
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Adaptation of SARS-CoV-2 to ACE2H353K mice reveals new spike residues that drive mouse infection
err2024-01-23
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errLi, Kun; Verma, Abhishek; Li, Pengfei; Ortiz, Miguel E.; Hawkins, Grant M.; Schnicker, Nicholas J.; Szachowicz, Peter J.; Pezullo, Alejandro; Wohlford-Lenane, Christine L.; Kicmal, Tom; Meyerholz, David K.; Gallagher, Tom; Perlman, Stanley; Mccray, Paul B.
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Dynamic measurement of airway surface liquid volume with an ex vivo trachea-chip
err2024-01-01
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errOAAI
errScott, Michael; Lei, Lei; Bierstedt, Kaleb C.; McCray, Paul B.; Xie, Yuliang
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Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo
err2023-12-05
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errOAAI
errKulhankova, Katarina; Traore, Soumba; Cheng, Xue; Benk-Fortin, Hadrien; Hallee, Stephanie; Harvey, Mario; Roberge, Joannie; Couture, Frederic; Kohli, Sajeev; Gross, Thomas J.; Meyerholz, David K.; Rettig, Garrett R.; Thommandru, Bernice; Kurgan, Gavin; Wohlford-Lenane, Christine; Hartigan-O'Connor, Dennis J.; Yates, Bradley P.; Newby, Gregory A.; Liu, David R.; Tarantal, Alice F.; Guay, David; McCray, Paul B., Jr.
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Avian influenza A viruses exhibit plasticity in sialylglycoconjugate receptor usage in human lung cells
err2023-11-30
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errLiang, Chieh-Yu; Huang, Iris; Han, Julianna; Sownthirarajan, Boopathi; Kulhankova, Katarina; Murray, Nathan B.; Taherzadeh, Mehrnoush; Archer-Hartmann, Stephanie; Pepi, Lauren; Manivasagam, Senthamizharasi; Plung, Jesse; Sturtz, Miranda; Yu, Yolanda; Vogel, Olivia A.; Kandasamy, Matheswaran; Gourronc, Francoise A.; Klingelhutz, Aloysius J.; Choudhury, Biswa; Rong, Lijun; Perez, Jasmine T.; Azadi, Parastoo; McCray, Paul B., Jr.; Neelamegham, Sriram; Manicassamy, Balaji
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CFTR-rich ionocytes mediate chloride absorption across airway epithelia
err2023-10-16
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errLei, Lei; Traore, Soumba; Ibarra, Guillermo S. Romano; Karp, Philip H.; Rehman, Tayyab; Meyerholz, David K.; Zabner, Joseph; Stoltz, David A.; Sinn, Patrick L.; Welsh, Michael J.; McCray Jr, Paul B.; Thornell, Ian M.
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Interleukin 13-Induced Inflammation Increases DPP4 Abundance but Does Not Enhance Middle East Respiratory Syndrome Coronavirus Replication in Airway Epithelia
err2023-09-12
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errLi, Kun; Bartlett, Jennifer A.; Wohlford-Lenane, Christine L.; Xue, Biyun; Thurman, Andrew L.; Gallagher, Thomas M.; Pezzulo, Alejandro A.; Mccray, Paul B.
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SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators
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IF4.7
err2023-02-28
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errOAAI
errHonrubia, Jose M.; Gutierrez-Alvarez, Javier; Sanz-Bravo, Alejandro; Gonzalez-Miranda, Ezequiel; Munoz-Santos, Diego; Castano-Rodriguez, Carlos; Wang, Li; Villarejo-Torres, Marta; Ripoll-Gomez, Jorge; Esteban, Ana; Fernandez-Delgado, Raul; Jose Sanchez-Cordon, Pedro; Oliveros, Juan Carlos; Perlman, Stanley; McCray Jr, Paul B.; Sola, Isabel; Enjuanes, Luis
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Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19
err2022-05-01
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errZheng, Jian; Wong, Lok-Yin Roy; Wilhelmsen, Kevin; Li, Kun; Ortiz, Miguel E.; Schnicker, Nicholas J.; Thurman, Andrew; Pezzulo, Alejandro A.; Szachowicz, Peter J.; Li, Pengfei; Pan, Ruangang; Klumpp, Klaus; Aswad, Fred; Rebo, Justin; Narumiya, Shuh; Murakami, Makoto; Zuniga, Sonia; Sola, Isabel; Enjuanes, Luis; Meyerholz, David K.; Fortney, Kristen; McCray, Paul B.; Perlman, Stanley
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Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform
err2021-12-23
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errOAAI
errStrub, Matthew D.; Ramachandran, Shyam; Boudko, Dmitri Y.; Meleshkevitch, Ella A.; Pezzulo, Alejandro A.; Subramanian, Aravind; Liberzon, Arthur; Bridges, Robert J.; McCray, Paul B., Jr.
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Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors
err2021-09-14
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errKrishnamurthy, Sateesh; Traore, Soumba; Cooney, Ashley L.; Brommel, Christian M.; Kulhankova, Katarina; Sinn, Patrick L.; Newby, Gregory A.; Liu, David R.; McCray, Paul B., Jr.
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