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收藏High throughput application of the NanoBiT Biochemical Assay for the discovery of selective p110a isoform binders that block its interaction with KRAS
Ismail, Mohamed (Soly) Soliman; Downward, Julian; Tart, Jonathan; Davies, Gareth; Monteverde, Tiziana; Hancock, David; Adhikari, Santosh; Stubbs, Christopher; Blackett, Carolyn; Holdgate, Geoff; Kettle, Jason 分享 收藏 Asbestos accelerates disease onset in a genetic model of malignant pleural mesotheliomaFarahmand, Pooyeh; Gyuraszova, Katarina; Rooney, Claire; Raffo-Iraolagoitia, Ximena L.; Jayasekera, Geeshath; Hedley, Ann; Johnson, Emma; Chernova, Tatyana; Malviya, Gaurav; Hall, Holly; Monteverde, Tiziana; Blyth, Kevin; Duffin, Rodger; Carlin, Leo M.; Lewis, David; Le Quesne, John; MacFarlane, Marion; Murphy, Daniel J. 分享 收藏 Optimizing the Cell Painting assay for image-based profiling优化基于图像的分析的细胞绘画分析Cimini, Beth A.; Chandrasekaran, Srinivas Niranj; Kost-Alimova, Maria; Miller, Lisa; Goodale, Amy; Fritchman, Briana; Byrne, Patrick; Garg, Sakshi; Jamali, Nasim; Logan, David J.; Concannon, John B.; Lardeau, Charles-Hugues; Mouchet, Elizabeth; Singh, Shantanu; Abbasi, Hamdah Shafqat; Aspesi, Jr Peter; Boyd, Justin D.; Gilbert, Tamara; Gnutt, David; Hariharan, Santosh; Hernandez, Desiree; Hormel, Gisela; Juhani, Karolina; Melanson, Michelle; Mervin, Lewis H.; Monteverde, Tiziana; Pilling, James E.; Skepner, Adam; Swalley, Susanne E.; Vrcic, Anita; Weisbart, Erin; Williams, Guy; Yu, Shan; Zapiec, Bolek; Carpenter, Anne E. 分享 收藏 Cell Morphological Profiling Enables High-Throughput Screening for PROteolysis TArgeting Chimera (PROTAC) Phenotypic SignatureTrapotsi, Maria-Anna; Mouchet, Elizabeth; Williams, Guy; Monteverde, Tiziana; Juhani, Karolina; Turkki, Riku; Miljkovic, Filip; Martinsson, Anton; Mervin, Lewis; Pryde, Kenneth R.; Mullers, Erik; Barrett, Ian; Engkvist, Ola; Bender, Andreas; Moreau, Kevin 分享 收藏 A KRAS-responsive long non-coding RNA controls microRNA processingShi, Lei; Magee, Peter; Fassan, Matteo; Sahoo, Sudhakar; Leong, Hui Sun; Lee, Dave; Sellers, Robert; Brulle-Soumare, Laura; Cairo, Stefano; Monteverde, Tiziana; Volinia, Stefano; Smith, Duncan D.; Di Leva, Gianpiero; Galuppini, Francesca; Paliouras, Athanasios R.; Zeng, Kang; O'Keefe, Raymond; Garofalo, Michela 分享 收藏 CKAP2L Promotes Non-Small Cell Lung Cancer Progression through Regulation of Transcription ElongationMonteverde, Tiziana; Sahoo, Sudhakar; La Montagna, Manuela; Magee, Peter; Shi, Lei; Lee, Dave; Sellers, Robert; Baker, Alexander R.; Leong, Hui Sun; Fassan, Matteo; Garofalo, Michela 分享 收藏 Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal AdenocarcinomaI型干扰素途径的抑制是胰腺导管腺癌中NK和b细胞的MYC和KRAS依赖性逃避的基础Muthalagu, Nathiya; Monteverde, Tiziana; Raffo-Iraolagoitia, Ximena; Wiesheu, Robert; Whyte, Declan; Hedley, Ann; Laing, Sarah; Kruspig, Bjorn; Upstill-Goddard, Rosanna; Shaw, Robin; Neidler, Sarah; Rink, Curtis; Karim, Saadia A.; Gyuraszova, Katarina; Nixon, Colin; Clark, William; Biankin, Andrew, V; Carlin, Leo M.; Coffelt, Seth B.; Sansom, Owen J.; Morton, Jennifer P.; Murphy, Daniel J. 分享 收藏 The ERBB network facilitates KRAS-driven lung tumorigenesisKruspig, Bjorn; Monteverde, Tiziana; Neidler, Sarah; Hock, Andreas; Kerr, Emma; Nixon, Colin; Clark, William; Hedley, Ann; Laing, Sarah; Coffelt, Seth B.; Le Quesne, John; Dick, Craig; Vousden, Karen; Martins, Carla P.; Murphy, Daniel J. 分享 收藏 分享 收藏 Colorectal Tumors Require NUAK1 for Protection from Oxidative StressPort, Jennifer; Muthalagu, Nathiya; Raja, Meera; Ceteci, Fatih; Monteverde, Tiziana; Kruspig, Bjorn; Hedley, Ann; Kalna, Gabriela; Lilla, Sergio; Neilson, Lisa; Brucoli, Martina; Gyuraszova, Katarina; Tait-Mulder, Jacqueline; Mezna, Mokdad; Svambaryte, Silvija; Bryson, Amy; Sumpton, David; McVie, Allan; Nixon, Colin; Drysdale, Martin; Esumi, Hiroyasu; Murray, Graeme I.; Sansom, Owen J.; Zanivan, Sara R.; Murphy, Daniel J. 分享 收藏 分享 收藏 Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivoHock, Andreas K.; Cheung, Eric C.; Humpton, Timothy J.; Monteverde, Tiziana; Paulus-Hock, Viola; Lee, Pearl; McGhee, Ewan; Scopelliti, Alessandro; Murphy, Daniel J.; Strathdee, Douglas; Blyth, Karen; Vousden, Karen H. 分享 收藏 The AMPK-related kinase NUAK1 is a target for treatment of colorectal cancerPort, J.; Muthalagu, N.; Raja, M.; Monteverde, T.; Mezna, M.; Ceteci, F.; Murray, G.; Sansom, O.; Zanivan, S.; Murphy, D. 分享 收藏 The ERBB network facilitates KRAS-driven lung tumorigenesisNeidler, S.; Hedley, A.; Kruspig, B.; Monteverde, T.; Hewit, K.; Neiswandt, B.; Rosenwald, A.; Shanks, E.; Dick, C.; Murphy, D. 分享 收藏 分享 收藏 
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