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Qingxiang Lin

Harvard University

H指数:8

被引数:368

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Spatially defined microenvironmental niches are associated with clinical outcome and tumor ecosystem diversity in head and neck cancer

空间定义的微环境小生境与头颈癌的临床结局及肿瘤生态系统多样性相关

IF11.8

2026-07-020

OAAI

Reversing Cell State-Dependent Adaptive Resistance to KRASG12D Blockade in KRASG12D-Mutant Pancreatic Cancer Through Vertical Pathway Inhibition

通过垂直通路抑制逆转KRASG12D突变胰腺癌中细胞状态依赖的适应性抵抗KRASG12D阻断

Journal of Pharmacology and Experimental Therapeutics

IF3.8

2026-05-010

PRE

Overcoming Cell Subtype-Specific Adaptive Resistance to KRAS G12D Inhibition in KRAS G12D-Mutant Pancreatic Cancer

CANCER RESEARCH

IF16.6

2024-09-150

PRE

Fibroblast growth factor receptor 1 inhibition suppresses pancreatic cancer chemoresistance and chemotherapy-driven aggressiveness

DRUG RESISTANCE UPDATES

IF21.7

2024-03-011

PRE

Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors

CLINICAL CANCER RESEARCH

IF10.2

2024-01-251

OA

Expression of fibroblast growth factor receptor 1 correlates inversely with the efficacy of single-agent fibroblast growth factor receptor-specific inhibitors in pancreatic cancer

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2024-01-222

PRE

Overcoming drug resistance of 'tri-complex' pan-RAS inhibitors: Inhibition of mTOR signaling

CANCER RESEARCH

IF16.6

2024-01-160

PRE

Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway

JOURNAL OF PROTEOME RESEARCH

IF3.6

2023-10-315

PRE

Comparative Proteomic Analysis Identifies Key Metabolic Regulators of Gemcitabine Resistance in Pancreatic Cancer

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2022-10-019

OAAI

Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression

ADVANCED SCIENCE

IF14.1

2020-03-1244

OAAI

FGFR1 inhibitor reverses Smoothened inhibition-induced epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2017-07-010

PRE

FGFR inhibitors enhance gemcitabine sensitivity in pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2017-07-010

PRE

LG-362B targets PML-RARα and blocks ATRA resistance of acute promyelocytic leukemia

IF13.4

2016-03-0819

OAAI

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-05-0125

PREAI

PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2014-07-0132

OAAI

Synthesis and Biological Evaluation of Novel Tetrahydro-β-carboline Derivatives as Antitumor Growth and Metastasis Agents through Inhibiting the Transforming Growth Factor-β Signaling Pathway

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-01-2765

PREAI

Polydatin suppresses ultraviolet B-induced cyclooxygenase-2 expression in vitro and in vivo via reduced production of reactive oxygen species

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2012-07-0515

PREAI

Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor-2

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-01-2677

OA