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Roselena Silvestri Schuh

hospital de clínicas de porto alegre
H指数:19
被引数:1,208
浏览量:0

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Liposomal CRISPR/Cas9-Mediated Local Genome Editing for Joint Disease in Mucopolysaccharidosis Type I

脂质体CRISPR/Cas9介导的局部基因组编辑在黏多糖贮积症I型关节疾病中的应用

Pharmaceutics
IF5.5
2026-02-260
OAAI
Hallana Souza Santos; Edina Poletto; Luisa Natalia Pimentel Vera; Mirian Farinon; Francyne Kubaski; Paola Barcelos Carneiro; Willian da Silva Carniel; Roberto Giugliani; Ursula Matte; Helder Ferreira Teixeira; Roselena Silvestri Schuh; Guilherme Baldo
Nanoemulsions as carriers for malignant brain tumors treatment: a scoping review on drugs, natural compounds, and siRNA delivery

纳米乳液作为恶性脑肿瘤治疗的载体：关于药物、天然化合物和siRNA递送的范畴综述

NANOMEDICINE
IF3.9
2025-11-010
PRE
Beltrame, Betina Montanari; Weimer, Patricia; Medeiros-Neves, Bruna; da Silva Gentil, Gabriela Figueira; Stefani, Marco Antonio; Velho, Maira; Fachel, Flavia Nathiely Silveira; Schuh, Roselena Silvestri; Braganhol, Elizandra; Teixeira, Helder Ferreira
An overview of the potentialities and recent advances in nanotechnology-based systems for glucocorticoids delivery

纳米技术为基础的糖皮质激素递送系统的潜力概述及最新进展

Journal of Drug Delivery Science and Technology
IF4.9
2025-10-150
PRE
Melaine Maiara da Silva Lopes; Luísa Degrandi Sehn; Rafaela Zimmermann; Helder Ferreira Teixeira; Ursula Matte; Roselena Silvestri Schuh; Flávia Nathiely Silveira Fachel
Recent Advances in Nose-to-Brain Gene Delivery for Central Nervous System Disorders

中枢神经系统疾病鼻腔给药基因递送的研究进展

Pharmaceutics 2025, Vol. 17, Page 1177
IF0
2025-09-100
OAAI
Flávia Nathiely Silveira Fachel; Angélica Salatino-Oliveira; Willian da Silva Carniel; Rafaela Zimmermann; Ursula Matte; Helder Ferreira Teixeira; Guilherme Baldo; Roselena Silvestri Schuh
Studies on the safety and irritability of eco-friendly extracts of Pterocaulon balansae Chodat (Asteraceae) standardized in coumarins aiming at topical application

关于Pterocaulon balansae Chodat（Asteraceae）生态友好型提取物（经香豆素标准化）安全性与刺激性研究，旨在用于局部应用

Fitoterapia
IF2.6
2025-05-180
PRE
Nathalya Tesch Brazil; Nicolly Espíndola Gelsleichter; Gabriela Nogueira Debom; Thassia Oliveira Lemos; Patrícia Weimer; Keli Cristine Reiter; Flávia Nathiely Silveira Fachel; Roselena Silvestri Schuh; Bruna Medeiros-Neves; Eduardo Cassel; Rubem Mario Figueiró Vargas; Fernanda Brião Menezes Boaretto; Jaqueline Nascimento Picada; Elizandra Braganhol; Gilsane Lino von Poser; Helder Ferreira Teixeira
Newborn Intravenous Injection of Liposomal CRISPR/Cas9 Complex Has No Incidence of Off-Targets or Tumors in Mice

新生小鼠经静脉注射脂质体CRISPR/Cas9复合物的实验中，未观察到脱靶效应或肿瘤发生。

PHARMACEUTICS
IF5.5
2025-05-170
OA
Monteagudo, Vinicius; Flores, Larissa Cristina Barbosa; Lopes, Melaine; Fachel, Flavia Nathiely Silveira; Martins, Giselle; Siebert, Marina; Carniel, Willian da Silva; Garcez, Tuane Nerissa Alves; Teixeira, Helder Ferreira; Matte, Ursula; Giugliani, Roberto; Baldo, Guilherme; Poletto, Edina; Schuh, Roselena Silvestri
Effects of chorionic mesenchymal stromal cells, their conditioned medium, and membrane particles on neutrophil functionality

绒毛膜间充质基质细胞、其条件培养基和膜颗粒对中性粒细胞功能的影响

CELL AND TISSUE RESEARCH
IF2.9
2025-04-220
PRE
Franco-da-Silva, Monique Maria; Aubin, Mariana Rauback; de Vasconcellos, Alessandra Amaral; Sirena, Dienifer Hermann; Marchaki, Giovana Bangel; Ruggeri, Laiza Rief; Hennigen, Andre Ferreira; Muradas, Thais; da Silveira, Ana Beatriz Tittoni; Braganhol, Elizandra; Schuh, Roselena Silvestri; Baldo, Guilherme; Araujo, Anelise Bergmann; Paz, Ana Helena
Evaluation of off-target events after an intravenous injection of liposomal CRISPR/Cas9 complex in vivo
MOLECULAR GENETICS AND METABOLISM
IF3.5
2025-02-010
PRE
Schuh, Roselena S.; de Barros, Vinicius M.; Lopes, Melaine M. S.; Fachel, Flavia N. S.; Carniel, Willian S.; Gonzalez, Esteban A.; Matte, Ursula; Giugliani, Roberto; Baldo, Guilherme; Poletto, Edina
Laronidase-loaded liposomes reach the brain and other hard-to-treat organs after noninvasive nasal administration
INTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
2024-07-010
PRE
Schuh, Roselena Silvestri; Francesch, Eduarda Piovesan; Brum, Bruna Brazeiro; Fachel, Flavia Nathiely Silveira; Poletto, Edina; Vera, Luisa Natalia Pimentel; Santos, Hallana Souza; Medeiros-Neves, Bruna; de Barros, Vinicius Monteagudo; Paz, Ana Helena da Rosa; Baldo, Guilherme; Matte, Ursula; Giugliani, Roberto; Teixeira, Helder Ferreira
Topical Nanoemulsions as Delivery Systems for Green Extracts of Pterocaulon balansae Aiming at the Treatment of Sporotrichosis
PHARMACEUTICS
IF5.5
2024-04-020
OAAI
Medeiros-Neves, Bruna; Heidrich, Daiane; Schuh, Roselena Silvestri; Brazil, Nathalya Tesch; Fachel, Flavia Nathiely Silveira; Cassel, Eduardo; Vargas, Rubem Mario Figueiro; Scroferneker, Maria Lucia; von Poser, Gilsane Lino; Koester, Leticia Scherer; Teixeira, Helder Ferreira
Intra-articular administration of nonviral vectors aminh at mucopolysaccharidosis type I mice gene editing
MOLECULAR GENETICS AND METABOLISM
IF3.5
2024-02-010
PRE
Schuh, Roselena S.; Souza, Leticia J.; Fachel, Flavia N. S.; Grudzinski, Patricia; Giugliani, Roberto; Gonzalez, Esteban A.; Baldo, Guilherme; Matte, Ursula
Bone disease in mucopolysaccharidosis type I: Morphological, structural and biomechanical characterization, and effect of different treatment approaches
MOLECULAR GENETICS AND METABOLISM
IF3.5
2024-02-010
PRE
Gonzalez, Esteban A.; Santos, Hallana S.; Leitune, Vicente C. B.; Gaviolli, Emanuela; Schuh, Roselena S.; Giugliani, Roberto; Baldo, Guilherme
Nasal administration of laronidase-loaded liposomes aiming at mucopolysaccharidosis type I treatment
MOLECULAR GENETICS AND METABOLISM
IF3.5
2023-02-010
PRE
Schuh, Roselena S.; Fachel, Flavia N. S.; Baldo, Guilherme; Teixeira, Helder F.; Matte, Ursula; Giugliani, Roberto
Drug Repositioning Applied to Cardiovascular Disease in Mucopolysaccharidosis
LIFE-BASEL
IF3.4
2022-12-121
OAAI
Villalba Silva, Gerda Cristal; Steindorff, Thiago; Silvestri Schuh, Roselena; Cardoso Flores, Natalia; Matte, Ursula
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses

治疗溶酶体疾病的基因编辑策略: 粘多糖的例子

ADVANCED DRUG DELIVERY REVIEWS
IF17.6
2022-12-017
PRE
Fachel, Flavia Nathiely Silveira; Francio, Lariane; Poletto, Edina; Schuh, Roselena Silvestri; Teixeira, Helder Ferreira; Giugliani, Roberto; Baldo, Guilherme; Matte, Ursula
Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system
JOURNAL OF GENE MEDICINE
IF2.2
2022-01-3113
PRE
Pimentel Vera, Luisa Natalia; Schuh, Roselena Silvestri; Silveira Fachel, Flavia Nathielly; Poletto, Edina; Piovesan, Eduarda; Kubaski, Francyne; Couto, Eduarda; Brum, Bruna; Rodrigues, Graziella; Souza, Hallana; Giugliani, Roberto; Matte, Ursula; Baldo, Guilherme; Teixeira, Helder F.
In Situ Gene Therapy

原位基因治疗

CURRENT GENE THERAPY
IF3.3
2021-12-236
PRE
Santos, Hallana Souza; Rodrigues, Luiza; Vera, Luisa Natalia Pimentel; Poletto, Edina; Filippi-Chiela, Eduardo; Bruschi, Lia Francie Ribeiro dos Santos; Schuh, Roselena; Baldo, Guilherme
Gene Therapy of Mucopolysaccharidosis Type I Mice: Repeated Administrations and Safety Assessment of pIDUA/Nanoemulsion Complexes

I型粘多糖贮积症小鼠的基因治疗: pIDUA/纳米乳液复合物的重复给药和安全性评估

CURRENT GENE THERAPY
IF3.3
2021-12-236
PRE
Fraga, Michelle; Schuh, Roselena Silvestri; Poletto, Edina; de Carvalho, Talita Giacomet; Franca, Raqueli Teresinha; Pinheiro, Camila Vieira; Baldo, Gilherme; Giugliani, Roberto; Teixeira, Helder Ferreira; Matte, Ursula
Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats
NEUROCHEMISTRY INTERNATIONAL
IF4
2020-12-0128
OAAI
Silveira Fachel, Flavia Nathiely; Michels, Luana Roberta; Azambuja, Juliana Hofstatter; Lenz, Gabriela Spies; Gelsleichter, Nicolly Espindola; Endres, Marcelo; Scholl, Juliete Nathali; Schuh, Roselena Silvestri; Barschak, Alethea Gatto; Figueiro, Fabricio; Bassani, Valquiria Linck; Henriques, Amelia Teresinha; Koester, Leticia Scherer; Teixeira, Helder Ferreira; Braganhol, Elizandra
CD73 siRNA therapy regulates glioblastoma immune microenvironment
MOLECULAR CANCER THERAPEUTICS
IF5.5
2019-12-010
PRE
Lenz, Gabriela Spies; Azambuja, Juliana Hofstatter; Schuh, Roselena Silvestri; Michels, Luana Roberta; Gelsleichter, Nicolly Espindola; Beckenkamp, Liziane Raquel; Roliano, Gabriela Goncalves; Figueiro, Frabricio; Scholl, Juliete N.; Sevigny, Jean; Wink, Marcia R.; Teixeira, Helder Ferreira; Braganhol, Elizandra

研究方向

暂未获取到该数据
H
Hélder Ferreira Teixeira
H 指数:38论文数:201被引数:4,602
Ú
Úrsula da Silveira Matte
H 指数:34论文数:549被引数:3,973
G
Guilherme Baldo
H 指数:24论文数:225被引数:1,812
F
Flávia Nathiely Silveira Fachel
H 指数:17论文数:51被引数:709
R
Roberto Giugliani
H 指数:80论文数:1,417被引数:2.4万
É
Édina Poletto
H 指数:15论文数:89被引数:591
E
Elizandra Braganhol
H 指数:41论文数:178被引数:4,876
E
Esteban Alberto Gonzalez
H 指数:13论文数:50被引数:592
B
Bruna Medeiros-Neves
H 指数:9论文数:20被引数:397
L
L. Koester
H 指数:37论文数:197被引数:4,654