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Ú

Úrsula da Silveira Matte

hospital de clínicas de porto alegre
H指数:34
被引数:3,973
浏览量:0

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Liposomal CRISPR/Cas9-Mediated Local Genome Editing for Joint Disease in Mucopolysaccharidosis Type I

脂质体CRISPR/Cas9介导的局部基因组编辑在黏多糖贮积症I型关节疾病中的应用

Pharmaceutics
IF5.5
2026-02-260
OAAI
Hallana Souza Santos; Edina Poletto; Luisa Natalia Pimentel Vera; Mirian Farinon; Francyne Kubaski; Paola Barcelos Carneiro; Willian da Silva Carniel; Roberto Giugliani; Ursula Matte; Helder Ferreira Teixeira; Roselena Silvestri Schuh; Guilherme Baldo
An overview of the potentialities and recent advances in nanotechnology-based systems for glucocorticoids delivery

纳米技术为基础的糖皮质激素递送系统的潜力概述及最新进展

Journal of Drug Delivery Science and Technology
IF4.9
2025-10-150
PRE
Melaine Maiara da Silva Lopes; Luísa Degrandi Sehn; Rafaela Zimmermann; Helder Ferreira Teixeira; Ursula Matte; Roselena Silvestri Schuh; Flávia Nathiely Silveira Fachel
Recent Advances in Nose-to-Brain Gene Delivery for Central Nervous System Disorders

中枢神经系统疾病鼻腔给药基因递送的研究进展

Pharmaceutics 2025, Vol. 17, Page 1177
IF0
2025-09-100
OAAI
Flávia Nathiely Silveira Fachel; Angélica Salatino-Oliveira; Willian da Silva Carniel; Rafaela Zimmermann; Ursula Matte; Helder Ferreira Teixeira; Guilherme Baldo; Roselena Silvestri Schuh
Newborn Intravenous Injection of Liposomal CRISPR/Cas9 Complex Has No Incidence of Off-Targets or Tumors in Mice

新生小鼠经静脉注射脂质体CRISPR/Cas9复合物的实验中，未观察到脱靶效应或肿瘤发生。

PHARMACEUTICS
IF5.5
2025-05-170
OA
Monteagudo, Vinicius; Flores, Larissa Cristina Barbosa; Lopes, Melaine; Fachel, Flavia Nathiely Silveira; Martins, Giselle; Siebert, Marina; Carniel, Willian da Silva; Garcez, Tuane Nerissa Alves; Teixeira, Helder Ferreira; Matte, Ursula; Giugliani, Roberto; Baldo, Guilherme; Poletto, Edina; Schuh, Roselena Silvestri
Evaluation of off-target events after an intravenous injection of liposomal CRISPR/Cas9 complex in vivo
MOLECULAR GENETICS AND METABOLISM
IF3.5
2025-02-010
PRE
Schuh, Roselena S.; de Barros, Vinicius M.; Lopes, Melaine M. S.; Fachel, Flavia N. S.; Carniel, Willian S.; Gonzalez, Esteban A.; Matte, Ursula; Giugliani, Roberto; Baldo, Guilherme; Poletto, Edina
Laronidase-loaded liposomes reach the brain and other hard-to-treat organs after noninvasive nasal administration
INTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
2024-07-010
PRE
Schuh, Roselena Silvestri; Francesch, Eduarda Piovesan; Brum, Bruna Brazeiro; Fachel, Flavia Nathiely Silveira; Poletto, Edina; Vera, Luisa Natalia Pimentel; Santos, Hallana Souza; Medeiros-Neves, Bruna; de Barros, Vinicius Monteagudo; Paz, Ana Helena da Rosa; Baldo, Guilherme; Matte, Ursula; Giugliani, Roberto; Teixeira, Helder Ferreira
Intra-articular administration of nonviral vectors aminh at mucopolysaccharidosis type I mice gene editing
MOLECULAR GENETICS AND METABOLISM
IF3.5
2024-02-010
PRE
Schuh, Roselena S.; Souza, Leticia J.; Fachel, Flavia N. S.; Grudzinski, Patricia; Giugliani, Roberto; Gonzalez, Esteban A.; Baldo, Guilherme; Matte, Ursula
Losartan treatment in mucopolysaccharidosis type I mice: Beneficial effects on aortic structure and pathways insights
MOLECULAR GENETICS AND METABOLISM
IF3.5
2024-02-010
PRE
Gonzalez, Esteban A.; Viana, Isabelle S.; Pimentel-Vera, Luisa N.; Testa, Giuseppe A.; Giugliani, Roberto; Matte, Ursula; Baldo, Guilherme
Identification of adverse drug reactions that may be related to pharmacogenetics in a public hospital in the South of Brazil
EXPERT OPINION ON DRUG SAFETY
IF3.1
2023-02-261
PRE
Camargo, Amanda C.; Matte, Ursula; Botton, Mariana R.
Nasal administration of laronidase-loaded liposomes aiming at mucopolysaccharidosis type I treatment
MOLECULAR GENETICS AND METABOLISM
IF3.5
2023-02-010
PRE
Schuh, Roselena S.; Fachel, Flavia N. S.; Baldo, Guilherme; Teixeira, Helder F.; Matte, Ursula; Giugliani, Roberto
Drug Repositioning Applied to Cardiovascular Disease in Mucopolysaccharidosis
LIFE-BASEL
IF3.4
2022-12-121
OAAI
Villalba Silva, Gerda Cristal; Steindorff, Thiago; Silvestri Schuh, Roselena; Cardoso Flores, Natalia; Matte, Ursula
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses

治疗溶酶体疾病的基因编辑策略: 粘多糖的例子

ADVANCED DRUG DELIVERY REVIEWS
IF17.6
2022-12-017
PRE
Fachel, Flavia Nathiely Silveira; Francio, Lariane; Poletto, Edina; Schuh, Roselena Silvestri; Teixeira, Helder Ferreira; Giugliani, Roberto; Baldo, Guilherme; Matte, Ursula
Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system
JOURNAL OF GENE MEDICINE
IF2.2
2022-01-3113
PRE
Pimentel Vera, Luisa Natalia; Schuh, Roselena Silvestri; Silveira Fachel, Flavia Nathielly; Poletto, Edina; Piovesan, Eduarda; Kubaski, Francyne; Couto, Eduarda; Brum, Bruna; Rodrigues, Graziella; Souza, Hallana; Giugliani, Roberto; Matte, Ursula; Baldo, Guilherme; Teixeira, Helder F.
Gene Therapy of Mucopolysaccharidosis Type I Mice: Repeated Administrations and Safety Assessment of pIDUA/Nanoemulsion Complexes

I型粘多糖贮积症小鼠的基因治疗: pIDUA/纳米乳液复合物的重复给药和安全性评估

CURRENT GENE THERAPY
IF3.3
2021-12-236
PRE
Fraga, Michelle; Schuh, Roselena Silvestri; Poletto, Edina; de Carvalho, Talita Giacomet; Franca, Raqueli Teresinha; Pinheiro, Camila Vieira; Baldo, Gilherme; Giugliani, Roberto; Teixeira, Helder Ferreira; Matte, Ursula
Which Is the Best In Silico Program for the Missense Variations in IDUA Gene? A Comparison of 33 Programs Plus a Conservation Score and Evaluation of 586 Missense Variants
FRONTIERS IN MOLECULAR BIOSCIENCES
IF4
2021-10-216
OAAI
Borges, Pamella; Pasqualim, Gabriela; Matte, Ursula
MPSBase: Comprehensive repository of differentially expressed genes for mucopolysaccharidoses
MOLECULAR GENETICS AND METABOLISM
IF3.5
2021-08-012
OAAI
Ferreira Soares, Luis Dias; Villalba Silva, Gerda Cristal; Kubaski, Francyne; Giugliani, Roberto; Matte, Ursula
Variants p.Pro2063Ser and p.Arg324*co-segregate in type 3 von Willebrand disease patients from Southern Brazil
HAEMOPHILIA
IF3
2021-02-061
PREAI
Ornaghi, Ana Paula; Meireles, Mariana Rost; Botton, Mariana Rodrigues; Salzano, Francisco Mauro; Bandinelli, Eliane; Matte, Ursula
Neuro-networks investigating the neurological impairment of mucopolysaccharidoses using a system biology approach
MOLECULAR GENETICS AND METABOLISM
IF3.5
2021-02-011
PREAI
Villalba Silva, Gerda Cristal; Matte, Ursula
MPSBase: Comprehensive repository of differentially expressed genes for mucopolysaccharidoses studies
MOLECULAR GENETICS AND METABOLISM
IF3.5
2021-02-010
PREAI
Ferreira Soares, Luis Dias; Villalba Silva, Gerda Cristal; Matte, Ursula da Silveira
Network Analysis Reveals Proteins Associated with Aortic Dilatation in Mucopolysaccharidoses

网络分析揭示了与粘多糖贮积症中主动脉扩张相关的蛋白质

INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES
IF3.9
2021-01-214
PREAI
Correa, Thiago; Feltes, Bruno Cesar; Gonzalez, Esteban Alberto; Baldo, Guilherme; Matte, Ursula

研究方向

暂未获取到该数据
R
Roberto Giugliani
H 指数:80论文数:1,417被引数:2.4万
G
Guilherme Baldo
H 指数:24论文数:225被引数:1,812
R
Roselena Silvestri Schuh
H 指数:19论文数:71被引数:1,208
H
Hélder Ferreira Teixeira
H 指数:38论文数:201被引数:4,602
É
Édina Poletto
H 指数:15论文数:89被引数:591
G
Gabriela Pasqualim
H 指数:16论文数:58被引数:645
F
Flávia Nathiely Silveira Fachel
H 指数:17论文数:51被引数:709
E
Esteban Alberto Gonzalez
H 指数:13论文数:50被引数:592
Â
Ângela Maria Vicente Tavares
H 指数:21论文数:109被引数:1,454
F
Fabiana Quoos Mayer
H 指数:25论文数:179被引数:2,387