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H

Hans Lennernäs

uppsala university

70H指数
360论文数
2.3W被引数
收录论文 125
发表时间
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Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats肠道渗透增强剂对ARV-471（一种蛋白水解靶向嵌合体）溶出和上皮转运的影响（大鼠）
errJournal of Controlled Release
IF11.5
err2026-09-09
err0
errOAAI
errJanis Niessen; Mirko Koziolek; Thomas Borchardt; Anura S. Indulkar; Benjamín J. Ortiz; Markus Sjöblom; Mikael Hedeland; Hans Lennernäs; David Dahlgren
err分享
err收藏
Characterization of hepatocellular carcinoma patient-derived organoids from patients receiving transarterial chemoembolization as a model for preclinical drug response assessment肝细胞癌患者来源类器官的表征：作为接受经动脉化疗栓塞患者预临床药物反应评估的模型
errScientific Reports
IF3.9
err2026-08-04
err0
errOAAI
errJaafar Khaled; Sofi Sennefelt Nyman; David Dahlgren; Fredrik Rorsman; Hans Lennernäs; Charlotte Ebeling Barbier; Femke Heindryckx
err分享
err收藏
The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)无定形药物纳米沉淀物对PROTACs ARV-110（Bavdeglutamide）和ARV-471（Vepdegestrant）肠道吸收的体内效应
errMolecular Pharmaceutics
IF4.5
err2026-04-30
err0
errOAAI
errJanis Niessen; Mirko Koziolek; Anura Indulkar; Thomas Borchardt; Markus Sjöblom; Mikael Hedeland; Hans Lennernäs; David Dahlgren
err分享
err收藏
Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signalingPERK通路药理学抑制调控肝癌细胞生长和免疫信号传导
errFEBS Open Bio
IF2.3
err2026-04-01
err0
errOAAI
errLerma-Clavero, Ada; Kopsida, Maria; Arendt, Nathalie; Lennernas, Hans; Sjoblom, Markus; Heindryckx, Femke
err分享
err收藏
Formulation breakthroughs driving broader tyrosine kinase use驱动酪氨酸激酶更广泛应用的开发突破
errBritish Journal of Clinical Pharmacology
IF3
err2026-02-01
err0
PREAI
errLennernas, Hans; Jesson, Gerald; Liljebris, Charlotta; Brisander, Magnus; Andersson, Claes-henrik; Andersson, Per; von Euler, Mikael; Stenke, Leif
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CombiCTx: Screening diffusion gradients of anti-cancer drug combinationsCombiCTx：抗癌药物组合的扩散梯度筛选
errlab chip
IF0
err2026-01-02
err0
errOAAI
errChristina Stelzl; Ada Lerma-Clavero; Selina Camenisch; Benoit Simon; Olle Eriksson; Oliver Degerstedt; Hans Lennernas; Femke Heindryckx; Johan Kreuger; Paul O'Callaghan
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err收藏
A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma化学诱导的肝癌小鼠模型中伊达比星与多柔比星的比较研究
errBiomedicine & Pharmacotherapy
IF7.5
err2025-12-04
err0
errOAAI
errAda Lerma-Clavero; Maria Kopsida; Nathalie Arendt; Hans Lennernäs; Markus Sjöblom; Femke Heindryckx
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Integrated Physiologically-based Pharmacokinetic Model with a Quantitative Systems Pharmacology and Toxicology Model for Statins in Disease Population. Part 2: MIDD and MIPD Applications整合基于生理学的药代动力学模型与定量系统药理学和毒理学模型用于他汀类药物在疾病人群中的应用。第二部分：MIDD和MIPD应用
errThe AAPS Journal
IF0
err2025-10-31
err0
errOAAI
errLuna Prieto Garcia; Pär Nordell; Christine Ahlström; Hans Lennernäs; Erik Sjögren
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err收藏
The Evolving Role of In Vitro–In Vivo Correlation in Model-Informed Drug Development: A Multi-Stakeholder Perspective体外-体内相关在模型引导药物开发中演变的角色：多利益相关方视角
errCPT: Pharmacometrics & Systems Pharmacology
IF0
err2025-10-28
err0
errOAAI
errMarylore Chenel; Sylvain Fouliard; Emma Hansson; Karl Brendel; Matthieu Jacobs; Hans Lennernäs; Erik Sjögren; Martin Bergstrand
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Statin-mediated protection in chemotherapy-induced intestinal and cardiac toxicity: current perspectives他汀类药物介导的保护在化疗诱导的肠道和心脏毒性中的作用：当前观点
errEuropean Journal of Pharmacology
IF4.7
err2025-10-23
err0
errOAAI
errNathalie Arendt; Maria Kopsida; Hans Lennernäs; Markus Sjöblom; Femke Heindryckx
err分享
err收藏
Integrated Physiologically-Based Pharmacokinetic Model with a Quantitative Systems Pharmacology and Toxicology Model for Statins in Disease Population. Part 1: Model Development and Validation整合生理基础药代动力学模型与定量系统药理学和毒理学模型用于疾病人群中的他汀类药物。第一部分：模型开发与验证
errThe AAPS Journal
IF0
err2025-10-06
err0
errOAAI
errLuna Prieto Garcia; Pär Nordell; Christine Ahlström; Hans Lennernäs; Erik Sjögren
err分享
err收藏
Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin在Huh-7肝癌细胞中绘制极性代谢组图谱揭示了阿托伐他汀增强多柔比星化疗疗效的作用
errJournal of Pharmaceutical and Biomedical Analysis
IF3.1
err2025-06-06
err0
errOAAI
errMaria Kopsida; Lotta Regtop; Hans Lennernäs; Mikael Hedeland; Femke Heindryckx; Mikael K.R. Engskog
err分享
err收藏
Therapeutic drug monitoring-Does it really matter?
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2024-12-30
err0
errOAAI
errLennernas, Hans; Cook, Jack; Hesselink, Dennis A.
err分享
err收藏
Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2024-10-01
err4
errOAAI
errNiessen, Janis; Nilsson, Jenny M.; Peters, Karsten; Indulkar, Anura; Borchardt, Thomas; Koziolek, Mirko; Lennernas, Hans; Dahlgren, David; Hedeland, Mikael
err分享
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Model-Based Interspecies Scaling for Predicting Human Pharmacokinetics of CB 4332, a Complement Factor I Protein
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-09-01
err0
errOAAI
errAlsoud, Rami Ayoun; Le Moan, Natacha; Holten-Andersen, Lars; Knudsen, Tom; Lennernas, Hans; Simonsson, Ulrika S. H.
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Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids
errANALYTICA CHIMICA ACTA
IF6
err2024-08-01
err1
errOAAI
errNilsson, Jenny M.; Balgoma, David; Pettersson, Curt; Lennernas, Hans; Heindryckx, Femke; Hedeland, Mikael
err分享
err收藏
Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2024-04-04
err2
errOAAI
errGarcia, Luna Prieto; Vildhede, Anna; Nordell, Par; Ahlstrom, Christine; Montaser, Ahmed B.; Terasaki, Tetsuya; Lennernas, Hans; Sjogren, Erik
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err收藏
Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells
errMOLECULAR METABOLISM
IF6.6
err2024-01-01
err6
errOAAI
errKopsida, Maria; Clavero, Ada Lerma; Khaled, Jaafar; Balgoma, David; -Marco, Clara Luna; Chowdhury, Azazul; Nyman, Sofi Sennefelt; Rorsman, Fredrik; Barbier, Charlotte Ebeling; Bergsten, Peter; Lennernaes, Hans; Hedeland, Mikael; Heindryckx, Femke
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err收藏
Quantitative imaging of doxorubicin diffusion and cellular uptake in biomimetic gels with human liver tumor cells
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2023-10-12
err3
errOAAI
errDegerstedt, Oliver; O'Callaghan, Paul; Clavero, Ada Lerma; Grasjo, Johan; Eriksson, Olle; Sjogren, Erik; Hansson, Per; Heindryckx, Femke; Kreuger, Johan; Lennernas, Hans
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Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2023-06-01
err27
errOAAI
errDahlgren, David; Lennernas, Hans
err分享
err收藏

研究方向

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合作学者
合作期刊
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Jan Tack
H 指数: 132 · 论文数: 2.1K
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O
Olle Eriksson
H 指数: 101 · 论文数: 1.3K
P
Per Artursson
H 指数: 94 · 论文数: 374
T
Teuvo L.J. Tammela
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