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Ikumi Tamai

kanazawa university

80H指数
495论文数
2.3W被引数
收录论文 157
发表时间
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Impact of renal hypoxia on OAT1 expression and adefovir-induced cytotoxicity in human 3D-RPTEC spheroids肾缺氧对OAT1表达及阿德福韦诱导的细胞毒性在人类3D-RPTEC微球体中的影响
errToxicology and Applied Pharmacology
IF3.4
err2026-04-03
err0
errOAAI
errItsuki Yokoseki; Masataka Nakano; Etsushi Takahashi; Kaoru Morimura; Yukiko Nishioka; Ayano Araki; Yoichi Jimbo; Naoki Ishiguro; Hiroshi Arawaka; Ikumi Tamai; Tatsuki Fukami; Miki Nakajima
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err收藏
Differential effects of osmotic fluid dynamics on intestinal drug absorption between juvenile and adult rats: potential impact on drug interaction with hyperosmotic beverages渗透性流体动力学对幼年与成年大鼠肠道药物吸收的差异化影响：与高渗饮料药物相互作用的潜在影响
errJournal of Pharmaceutical Sciences
IF3.8
err2026-03-03
err0
PREAI
errKazuki Hotta; Tomoki Ishii; Asuka Kichijima; Ayaka Maejima; Ikumi Tamai; Yoshiyuki Shirasaka
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Quantitative analysis of the effect of controlled-release formulation on nonlinear gastrointestinal absorption of CYP3A4 substrate simvastatin using a physiologically based pharmacokinetic absorption model采用生理药代动力学吸收模型对控释制剂对CYP3A4底物辛伐他汀非线性胃肠道吸收的影响进行定量分析
errJournal of Drug Delivery Science and Technology
IF4.9
err2026-02-23
err0
PREAI
errEmika Murayama; Peter Langguth; Ikumi Tamai; Yoshiyuki Shirasaka
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3D-cultured renal tubular model reveals FXR-HNF4α-OAT1/3 axis as a target for preventing nucleotide analog-induced kidney injury3D培养的肾小管模型揭示了FXR-HNF4α-OAT1/3轴可作为预防核苷类似物诱导的肾损伤的靶点
errDrug Metabolism and Disposition
IF4
err2025-12-04
err0
errOAAI
errItsuki Yokoseki; Masataka Nakano; Etsushi Takahashi; Kaoru Morimura; Yukiko Nishioka; Ayano Araki; Yoichi Jimbo; Naoki Ishiguro; Hiroshi Arawaka; Ikumi Tamai; Tatsuki Fukami; Miki Nakajima
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Contribution of Japanese scientists to drug metabolism and disposition日本科学家对药物代谢和分布的贡献
errDRUG METABOLISM AND DISPOSITION
IF4
err2025-05-01
err0
PREAI
errNakajima, Miki; Yamazaki, Hiroshi; Yoshinari, Kouichi; Kobayashi, Kaoru; Ishii, Yuji; Nakai, Daisuke; Kamimura, Hidetaka; Kume, Toshiyuki; Saito, Yoshiro; Maeda, Kazuya; Kusuhara, Hiroyuki; Tamai, Ikumi
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How the Magenstrasse is formed after meals: Protein aggregation hypothesis
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2025-02-01
err0
PREAI
errSakai, Ryosuke; Shirasaka, Yoshiyuki; Takagi, Taiyo; Masada, Takato; Minami, Keiko; Kataoka, Makoto; Tamai, Ikumi; Takagi, Toshihide; Yamashita, Shinji
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Functional identification of soluble uric acid as an endogenous inhibitor of CD38可溶性尿酸作为CD38内源性抑制剂的功能鉴定
errELIFE
IF0
err2024-11-11
err0
errOAAI
errWen, Shijie; Arakawa, Hiroshi; Yokoyama, Shigeru; Shirasaka, Yoshiyuki; Higashida, Haruhiro; Tamai, Ikumi
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Contributions of multiple transport mechanisms to intestinal uptake of serotonin多种转运机制对5-羟色胺肠道摄取的贡献
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-11-01
err0
PREAI
errAsaji, Suguru; Funai, Yuta; Seki, Yuta; Tamai, Ikumi; Shirasaka, Yoshiyuki
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Three-dimensional culture of human proximal tubular epithelial cells for an in vitro evaluation of drug-induced kidney injury三维培养人近端肾小管上皮细胞体外评价药物性肾损伤
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-11-01
err2
errOAAI
errArakawa, Hiroshi; Higuchi, Daichi; Takahashi, Etsushi; Matsushita, Kohei; Nedachi, Shiho; Peng, Hanwei; Kadoguchi, Moeno; Morimura, Kaoru; Araki, Ayano; Kondo, Masayuki; Ishiguro, Naoki; Jimbo, Yoichi; Tamai, Ikumi
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Unique Binding Sites of Uricosuric Agent Dotinurad for Selective Inhibition of Renal Uric Acid Reabsorptive Transporter URAT1
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2024-07-01
err1
errOAAI
errFujita, Kazuki; Isozumi, Noriyoshi; Zhu, Qiunan; Matsubayashi, Masaya; Taniguchi, Tetsuya; Arakawa, Hiroshi; Shirasaka, Yoshiyuki; Mori, Eiichiro; Tamai, Ikumi
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Prediction and causal inference of hyperuricemia using gut microbiota
errSCIENTIFIC REPORTS
IF3.9
err2024-04-30
err4
errOAAI
errMiyajima, Yuna; Karashima, Shigehiro; Mizoguchi, Ren; Kawakami, Masaki; Ogura, Kohei; Ogai, Kazuhiro; Koshida, Aoi; Ikagawa, Yasuo; Ami, Yuta; Zhu, Qiunan; Tsujiguchi, Hiromasa; Hara, Akinori; Kurihara, Shin; Arakawa, Hiroshi; Nakamura, Hiroyuki; Tamai, Ikumi; Nambo, Hidetaka; Okamoto, Shigefumi
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Uric acid in health and disease: From physiological functions to pathogenic mechanisms
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2024-04-01
err26
PREAI
errWen, Shijie; Arakawa, Hiroshi; Tamai, Ikumi
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Role of Organic Anion Transporter NPT4 in Renal Handling of Uremic Toxin 3-indoxyl Sulfate
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-04-01
err1
PREAI
errImamura, Rikako; Sugimoto, Masahiro; Horike, Shin-ichi; Terakawa, Jumpei; Fujita, Kazuki; Tamai, Ikumi; Daikoku, Takiko; Kato, Yukio; Arakawa, Hiroshi
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Drug-drug conjugates of MEK and Akt inhibitors for RAS-mutant cancers
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2024-03-01
err4
PREAI
errFujita, Hikaru; Arai, Sachiko; Arakawa, Hiroshi; Hamamoto, Kana; Kato, Toshiyuki; Arai, Tsubasa; Nitta, Nanaka; Hotta, Kazuki; Hosokawa, Natsuko; Ohbayashi, Takako; Takahashi, Chiaki; Inokuma, Yasuhide; Tamai, Ikumi; Yano, Seiji; Kunishima, Munetaka; Watanabe, Yoshihiro
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Quantitative analysis of gastrointestinal fluid absorption and secretion to estimate luminal fluid dynamics in rats
errSCIENTIFIC REPORTS
IF3.9
err2023-10-14
err2
errOAAI
errFunai, Yuta; Ichijo, Kazuki; Suzuki, Satoru; Tateishi, Yuta; Inoue, Katsuhisa; Tamai, Ikumi; Shirasaka, Yoshiyuki
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Induction of open-form bile canaliculus formation by hepatocytes for evaluation of biliary drug excretion
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-08-22
err4
errOAAI
errArakawa, Hiroshi; Nakazono, Yuya; Matsuoka, Natsumi; Hayashi, Momoka; Shirasaka, Yoshiyuki; Hirao, Atsushi; Tamai, Ikumi
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A Novel In Vitro Hepatocyte Culture System (icHep) for Biliary Drug Excretion Analysis Using Permeation Assay
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errNakazono, Yuya; Arakawa, Hiroshi; Matsuoka, Natsumi; Shirasaka, Yoshiyuki; Tamai, Ikumi
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Quantitative Analysis of Gastrointestinal Water Dynamics by Means of a Physiologically Based Fluid Kinetic Model
errAAPS JOURNAL
IF3.7
err2023-04-20
err2
PREAI
errSuzuki, Satoru; Inoue, Katsuhisa; Tamai, Ikumi; Shirasaka, Yoshiyuki
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Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally
errPHARMACEUTICAL RESEARCH
IF4.3
err2023-04-20
err1
errOAAI
errNakajima, Miki; Tamai, Ikumi
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Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs
errPHARMACEUTICS
IF5.5
err2023-02-02
err1
errOAAI
errSato, Kakeru; Mizutani, Asuka; Muranaka, Yuka; Yao, Jianwei; Kobayashi, Masato; Yamazaki, Kana; Nishii, Ryuichi; Nishi, Kodai; Nakanishi, Takeo; Tamai, Ikumi; Kawai, Keiichi
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研究方向

暂无研究方向
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