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Sanduo Zheng

Tsinghua University

H指数:25

被引数:2,705

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Molecular-dynamics-simulation-guided directed evolution of flavoenzymes for atroposelective desaturation

分子动力学模拟指导的 flavoenzymes 的对映选择性脱饱和定向进化

Nature Synthesis

IF20

2025-09-100

PRE

SARM1 activation promotes axonal degeneration via a two-step phase transition

SARM1激活通过两步相变促进轴突退化

Nature Chemical Biology

IF13.7

2025-08-220

PRE

Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic

通过生物合成型NMN模拟物揭示SARM1的逐步激活介导细胞死亡和轴突退化。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-02-180

OA

Zinc transporter 1 functions in copper uptake and cuproptosis

CELL METABOLISM

IF30.9

2024-09-013

PRE

Specific binding of GPR174 by endogenous lysophosphatidylserine leads to high constitutive Gs signaling

NATURE COMMUNICATIONS

IF15.7

2023-09-226

OAAI

Structural basis for the ubiquitination of G protein βγ subunits by KCTD5/Cullin3 E3 ligase

KCTD5/Cullin3 E3连接酶对g蛋白 β γ 亚基泛素化的结构基础

SCIENCE ADVANCES

IF12.5

2023-07-1411

OAAI

Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction

CELL CHEMICAL BIOLOGY

IF7.2

2023-03-0112

OAAI

In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein

ACS CENTRAL SCIENCE

IF10.4

2023-02-0818

OAAI

A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety

一种选择性靶向实体瘤并提高疗效和安全性的pH依赖性anti-CD47抗体

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2023-01-1713

OAAI

Molecular basis for the selective G protein signaling of somatostatin receptors

NATURE CHEMICAL BIOLOGY

IF13.7

2022-09-2216

PRE

Structural insights into G protein activation by D1 dopamine receptor

D1多巴胺受体激活g蛋白的结构洞察

SCIENCE ADVANCES

IF12.5

2022-06-1016

OAAI

Ligand recognition and biased agonism of the D1 dopamine receptor

NATURE COMMUNICATIONS

IF15.7

2022-06-0821

OAAI

Structural insights into galanin receptor signaling

甘丙肽受体信号传导的结构见解

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-05-2015

OAAI

A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the

IF6.9

2022-05-0113

OA

High-Throughput Mutagenesis and Cross-Complementation Experiments Reveal Substrate Preference and Critical Residues of the Capsule Transporters in Streptococcus pneumoniae

高通量诱变和交叉互补实验揭示了肺炎链球菌荚膜转运蛋白的底物偏好和关键残基

IF4.7

2021-12-219

OAAI

Cryo-electron Microscopy Structure of S-Trimer, a Subunit Vaccine Candidate for COVID-19

JOURNAL OF VIROLOGY

IF3.8

2021-05-1027

OAAI

Mapping and engineering the interaction between adiponectin and T-cadherin

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-02-0125

OAAI

Ion Channels: Solving a specificity mystery

IF0

2019-01-160

OA

Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-06-1155

OAAI

Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate

IF12.8

2018-03-1957

OAAI