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Andrew C. Kruse

Harvard Medical School

61H指数
214论文数
2.0W被引数
收录论文 64
发表时间
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GPCR antagonism via rewiring of receptor trafficking and degradation通过重编程受体转运和降解实现GPCR拮抗
errNature
IF48.5
err2026-09-30
err0
errOAAI
errKaitlin Rhee; Lawrence Shue; Akimasa Adachi; Pengwei Sun; James Osei-Owusu; Dingjingyu Zhou; Aoxing Cheng; Yi Ran Xu; Qingyue Li; Apoorva Baluapuri; Edward P. Harvey; Karen Adelman; Meredith A. Skiba; Bianxiao Cui; Jun R. Huh; Andrew C. Kruse; Xin Zhou
err分享
err收藏
Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design灵长类志贺氏菌暴发产生的多功能抗体反应为疫苗设计提供信息
errScience Translational Medicine
IF14.6
err2026-09-02
err0
PREAI
errRobert M. Gallant; Paul Savarino; Sophia Pulido; Morgan S. A. Gilman; Ti Lu; Jennifer Hayes; Nicholas L. Xerri; Torrey Williams; Mark A. Ochoa; Zackary Dietz; Eric Peterson; Timothy Scott; Faye Hartmann; Stephen G. Baker; Robert W. Kaminski; Devin Sok; Andrew C. Kruse; Wendy Picking; Saverio V. Capuano; Hayden R. Schmidt
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err收藏
β-arrestin recruitment facilitates a direct association with G proteinsβ-arrestin招募促进与G蛋白的直接结合
errNature Communications
IF15.7
err2026-07-17
err0
errOAAI
errClaudia Y. Lee; Jeffrey S. Smith; Taylor Kohlmann; Emily M. Meara; Uyen Pham; Frank Kwarcinski; Andrew N. Dates; Jessica K. Orofino; Issac Choi; Ari S. Hilibrand; Chanpreet Jassal; Abigail Gilmer; Stephen C. Blacklow; Gregory G. Tall; Andrew C. Kruse; Sudarshan Rajagopal
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A Simple and Cost-Effective Electrochemical Assay for Heart Failure Prognosis Using Soluble Suppression of Tumorigenicity 2-Specific Nanobodies一种用于心力衰竭预后预测的简单且经济有效的电化学检测方法，使用可溶性肿瘤抑制因子2特异性纳米抗体
errACS Pharmacology & Translational Science
IF3.7
err2026-06-05
err0
errOAAI
errSuwitchaya Sirimanakul; Joseph D. Hurley; Nakarin Vutipow; Fabien Loison; Anongnard Kasorn; Lueacha Tabtimmai; Pinpunya Riangrungroj; Jeerapond Leelawattanachai; Teetouch Ananwattanasuk; Napachanok Swainson; Kiattawee Choowongkomon; Andrew C. Kruse; Dujduan Waraho-Zhmayev
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In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer利用AlphaFold-Multimer进行G蛋白偶联受体纳米抗体结合物的计算机模拟发现
errNature Communications
IF15.7
err2026-04-23
err0
errOAAI
errEdward P. Harvey; Jeffrey S. Smith; Joseph D. Hurley; Alyana J. Granados; Ernst W. Schmid; Jason G. Liang-Lin; Huyang Zhang; Emily M. Meara; Elizabeth K. Wren; Steffanie Paul; Matthew P. Ferguson; Victor G. Calvillo-Miranda; Miguel A. Alcantar; Debora S. Marks; Johannes C. Walter; Andrew C. Kruse; Katherine J. Susa
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err收藏
Isolation of Antigen-Specific Nanobodies From Synthetic Libraries Using a Protein Selection Strategy That Combines MACS-Based Screening of YSD and FLI-TRAP利用结合MACS基筛选YSD和FLI-TRAP的蛋白质选择策略从合成文库中分离抗原特异性纳米抗体
errBIO-PROTOCOL
IF1.1
err2026-01-20
err0
PREAI
errThaiprayoon, Apisitt; Chantarasorn, Yodpong; Oonanant, Worrapoj; Kasorn, Anongnard; Longsompurana, Phoomintara; Tapaneeyakorn, Satita; Riangrungroj, Pinpunya; Loison, Fabien; Kruse, Andrew C.; Delisa, Matthew P.; Waraho-Zhmaye, Dujduan
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Structural Insights into Antibody-based Inhibition of the Angiotensin Receptor
errMicroscopy and Microanalysis
IF3
err2025-07-25
err0
PREAI
errMeredith A Skiba; Sarah M Sterling; Shaun Rawson; Morgan S A Gilman; Andrew C Kruse
err分享
err收藏
The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch细胞壁合成的肇事逃逸: LpoB通过保守的变构开关瞬时结合并激活PBP1b
errNature Communications
IF15.7
err2025-07-21
err0
errOAAI
errIrina Shlosman; Andrea Vettiger; Thomas G. Bernhardt; Andrew C. Kruse; Joseph J. Loparo
err分享
err收藏
G Protein Selectivity in Dopamine Receptors is Determined before GDP ReleaseG蛋白选择性在多巴胺受体中是在GDP释放之前确定的
errBIOCHEMISTRY
IF3
err2025-05-13
err0
errOAAI
errTawfeeq, Caesar; Hilibrand, Ari S.; Smith, Jeffrey S.; Portillo, Jennifer; Kruse, Andrew C.; Abrol, Ravinder
err分享
err收藏
Epitope-directed selection of GPCR nanobody ligands with evolvable function表位导向的GPCR纳米抗体配体选择，具有可进化功能
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2025-03-11
err0
errOAAI
errSkiba, Meredith A.; Canavan, Clare; Nemeth, Genevieve R.; Liu, Jinghan; Kanso, Ali; Kruse, Andrew C.
err分享
err收藏
Isolation of PCSK9-specific nanobodies from synthetic libraries using a combined protein selection strategy
errSCIENTIFIC REPORTS
IF3.9
err2025-01-28
err0
errOAAI
errThaiprayoon, Apisitt; Chantarasorn, Yodpong; Oonanant, Worrapoj; Kasorn, Anongnard; Longsompurana, Phoomintara; Tapaneeyakorn, Satita; Riangrungroj, Pinpunya; Loison, Fabien; Kruse, Andrew C.; Delisa, Matthew P.; Waraho-Zhmayev, Dujduan
err分享
err收藏
Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors粘附g蛋白偶联受体中束缚激动剂信号的异质性
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-08-01
err4
PREAI
errDates, Andrew N.; Jones, Daniel T. D.; Smith, Jeffrey S.; Skiba, Meredith A.; Rich, Maria F.; Burruss, Maggie M.; Kruse, Andrew C.; Blacklow, Stephen C.
err分享
err收藏
A spatiotemporal map of co-receptor signaling networks underlying B cell activation
errCELL REPORTS
IF6.9
err2024-06-01
err1
errOAAI
errSusa, Katherine J.; Bradshaw, Gary A.; Eisert, Robyn J.; Schilling, Charlotte M.; Kalocsay, Marian; Blacklow, Stephen C.; Kruse, Andrew C.
err分享
err收藏
Tetraspanins: structure, dynamics, and principles of partner-protein recognition
errTRENDS IN CELL BIOLOGY
IF18.1
err2024-06-01
err10
PREAI
errSusa, Katherine J.; Kruse, Andrew C.; Blacklow, Stephen C.
err分享
err收藏
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein FamiliesS
errMOLECULAR PHARMACOLOGY
IF3
err2024-06-01
err1
errOAAI
errSmith, Jeffrey S.; Hilibrand, Ari S.; Skiba, Meredith A.; Dates, Andrew N.; Calvillo-Miranda, Victor G.; Kruse, Andrew C.
err分享
err收藏
Antibodies expand the scope of angiotensin receptor pharmacology
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-05-14
err4
PREAI
errSkiba, Meredith A.; Sterling, Sarah M.; Rawson, Shaun; Zhang, Shuhao; Xu, Huixin; Jiang, Haoran; Nemeth, Genevieve R.; Gilman, Morgan S. A.; Hurley, Joseph D.; Shen, Pengxiang; Staus, Dean P.; Kim, Jihee; McMahon, Conor; Lehtinen, Maria K.; Rockman, Howard A.; Barth, Patrick; Wingler, Laura M.; Kruse, Andrew C.
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err收藏
Allosteric activation of cell wall synthesis during bacterial growth
errNATURE COMMUNICATIONS
IF15.7
err2023-06-10
err10
errOAAI
errShlosman, Irina; Fivenson, Elayne M. M.; Gilman, Morgan S. A.; Sisley, Tyler A. A.; Walker, Suzanne; Bernhardt, Thomas G. G.; Kruse, Andrew C. C.; Loparo, Joseph J. J.
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The relaxin receptor RXFP1 signals through a mechanism of autoinhibition
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-04-20
err7
errOAAI
errErlandson, Sarah C.; Rawson, Shaun; Osei-Owusu, James; Brock, Kelly P.; Liu, Xinyue; Paulo, Joao A.; Mintseris, Julian; Gygi, Steven P.; Marks, Debora S.; Cong, Xiaojing; Kruse, Andrew C.
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An in silico method to assess antibody fragment polyreactivity
errNATURE COMMUNICATIONS
IF15.7
err2022-12-07
err15
errOAAI
errHarvey, Edward P.; Shin, Jung-Eun; Skiba, Meredith A.; Nemeth, Genevieve R.; Hurley, Joseph D.; Wellner, Alon; Shaw, Ada Y.; Miranda, Victor G.; Min, Joseph K.; Liu, Chang C.; Marks, Debora S.; Kruse, Andrew C.
err分享
err收藏
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-09-12
err6
errOAAI
errLi, Qi; Humphries, Fiachra; Girardin, Roxie C.; Wallace, Aaron; Ejemel, Monir; Amcheslavsky, Alla; McMahon, Conor T.; Schiller, Zachary A.; Ma, Zepei; Cruz, John; Dupuis, Alan P.; Payne, Anne F.; Maryam, Arooma; Yilmaz, Nese Kurt; McDonough, Kathleen A.; Pierce, Brian G.; Schiffer, Celia A.; Kruse, Andrew C.; Klempner, Mark S.; Cavacini, Lisa A.; Fitzgerald, Katherine A.; Wang, Yang
err分享
err收藏

研究方向

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合作学者
合作期刊
I
Irving L. Weissman
H 指数: 215 · 论文数: 1.3K
R
Robert J. Lefkowitz
H 指数: 213 · 论文数: 858
S
Steven P. Gygi
H 指数: 195 · 论文数: 1.0K
C
Chris Sander
H 指数: 191 · 论文数: 849
J
Joseph Schlessinger
H 指数: 174 · 论文数: 719
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