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收藏α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistanceα-synuclein在胶质母细胞瘤中的表达恢复了肿瘤抑制功能并挽救了替莫唑胺耐药性
Duplan, Eric; Bernardin, Aurore; Goiran, Thomas; Leroudier, Nathalie; Casimiro, Mathew; Pestell, Richard; Tanaka, Shinya; Malleval, Celine; Honnorat, Jerome; Idbaih, Ahmed; Martin, Lucie; Castel, Helene; Checler, Frederic; Alves da Costa, Cristine
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收藏The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ production
Afram, Elissa; Lauritzen, Inger; Bourgeois, Alexandre; El Manaa, Wejdane; Duplan, Eric; Chami, Mounia; Valverde, Audrey; Charlotte, Bauer; Pardossi-Piquard, Raphaelle; Checler, Frederic
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收藏Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiologyXBP1s和PINK1之间的功能相互作用的转录和磷酸化依赖性控制线粒体自噬并可能影响帕金森病的病理生理
El Manaa, Wejdane; Duplan, Eric; Goiran, Thomas; Lauritzen, Inger; Vaillant Beuchot, Loan; Lacas-Gervais, Sandra; Morais, Vanessa Alexandra; You, Han; Qi, Ling; Salazar, Mario; Ozcan, Umut; Chami, Mounia; Checler, Frederic; Alves da Costa, Cristine
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收藏Upregulation of the Sarco-Endoplasmic Reticulum Calcium ATPase 1 Truncated Isoform Plays a Pathogenic Role in Alzheimer's Disease肌内质网钙atp酶1截短亚型的上调在阿尔茨海默氏病中起致病作用
Bussiere, Renaud; Oules, Benedicte; Mary, Arnaud; Vaillant-Beuchot, Loan; Martin, Cecile; El Manaa, Wejdane; Vallee, Deborah; Duplan, Eric; Paterlini-Brechot, Patrizia; Da Costa, Cristine Alves; Checler, Frederic; Chami, Mounia
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收藏β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models
Goiran, Thomas; Duplan, Eric; Chami, Mounia; Bourgeois, Alexandre; El Manaa, Wejdane; Rouland, Lila; Dunys, Julie; Lauritzen, Inger; You, Han; Stambolic, Vuk; Biferi, Maria-Grazia; Barkats, Martine; Pimplikar, Sanjay W.; Sergeant, Nicolas; Colin, Morvane; Morais, Vanessa A.; Pardossi-Piquard, Raphaelle; Checler, Frederic; da Costa, Cristine Alves
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收藏The extracellular regulated kinase-1 (ERK1) controls regulated α-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein (vol 286, pg 29192, 2011)
Cisse, Moustapha; Duplan, Eric; Guillot-Sestier, Marie-Victoire; Rumigny, Joaquim; Bauer, Charlotte; Pages, Gilles; Orzechowski, Hans-Dieter; Slack, Barbara E.; Checler, Frederic; Vincent, Bruno
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