Antiviral activity of GS-5801, a liver-targeted prodrug of a lysine demethylase 5 inhibitor, in a hepatitis B virus primary human hepatocyte infection modelJOURNAL OF HEPATOLOGYIF332017-01-0128PREAI
Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical BiologyJOURNAL OF MEDICINAL CHEMISTRYIF6.82016-12-2253PREAI
Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease InhibitorsANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52016-01-0168OAAI
Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of ActionJOURNAL OF MEDICINAL CHEMISTRYIF6.82015-05-0473PREAI
NON-SYNONYMOUS SINGLE-NUCLEOTIDE POLYMORPHISMS (SNPS) IN TLR7 DO NOT IMPACT GS-9620 DEPENDENT TLR7 ACTIVATIONJOURNAL OF HEPATOLOGYIF332015-04-010PREAI
Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistatKIDNEY INTERNATIONALIF12.62014-08-01218OAAI
Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate ProdrugANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52014-04-0136OA
Metabolism and Pharmacokinetics of the Anti-Hepatitis C Virus Nucleotide Prodrug GS-6620ANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52014-04-0138OAAI
Multiple Classes of Antiviral Agents Exhibit In Vitro Activity against Human Rhinovirus Type CANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52014-03-0143OAAI
Evaluation of the Effect of Cobicistat on the In Vitro Renal Transport and Cytotoxicity Potential of TenofovirANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52013-10-0142OAAI
Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosidesBIOORGANIC & MEDICINAL CHEMISTRYIF32012-09-0134PRE
Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosinesJOURNAL OF MEDICINAL CHEMISTRYIF6.82011-07-11111PREAI
Role of Cathepsin A and Lysosomes in the Intracellular Activation of Novel Antipapillomavirus Agent GS-9191ANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52011-05-0125OAAI
Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosidesBIOORGANIC & MEDICINAL CHEMISTRYIF32011-01-0131PREAI
CycloSal-phosphate Pronucleotides of Cytostatic 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Cytostatic Activity, and Inhibition of Adenosine KinasesCHEMMEDCHEMIF3.42010-07-2331PREAI
Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug DesignJOURNAL OF MEDICINAL CHEMISTRYIF6.82010-05-27216PREAI
Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148BIOORGANIC & MEDICINAL CHEMISTRYIF32010-05-0163PRE
6-(Het)aryl-7-Deazapurine Ribonucleosides as Novel Potent Cytostatic AgentsJOURNAL OF MEDICINAL CHEMISTRYIF6.82009-11-24138PREAI
GS-9191 Is a Novel Topical Prodrug of the Nucleotide Analog 9-(2-Phosphonylmethoxyethyl)Guanine with Antiproliferative Activity and Possible Utility in the Treatment of Human Papillomavirus LesionsANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52009-07-0140OAAI
Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugsPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAIF9.12009-05-1935OAAI