张迪 (Di Zhang)

Central South University讲师

H指数:27

被引数:2,723

个人简介

"姓名：张迪职称：讲师研究方向：当归四逆汤方证研究、抑郁症相关方证研究电子邮箱：dizhang0915@jnu.edu.cn个人简介：张迪，男，中共党员，2023年获中西医结合博士学位。\n主要从事中医方证相关研究，聚焦于中枢/外周神经系统/心脑血管系统疾病的机制研究。主持获批课题7项，第一作者及共同通讯作者发表SCI论文20篇。担任中国民族医药学会方药量效研究分会理事、担任Chinese Medicine、Traditional Medicine Research（优秀青年编委）、Interdisciplinary Sciences: Computational Life Sciences青年编委、指导学生团队荣获第十七届全国大学生创新年会“我最喜爱的项目”及“最佳创意项目”。\n更新时间：2025年9月12日\n教学/科研成果\n1.课题：（1）国家自然科学基金青年基金（青C），基于Angptl4/Sdc4调控内皮细胞-施万细胞耦联探究当归四逆汤改善神经微循环促进神经修复治疗坐骨神经痛，主持（2）广东省基础与应用基础研究基金自然科学基金面上项目，当归四逆汤抑制SPP1/CD44介导的巨噬细胞-施万细胞串扰促进损伤神经修复治疗坐骨神经痛，主持（3）广州市博士启航计划，当归四逆汤调节Angptl4/Sdc4介导的血管神经耦联促进损伤神经修复治疗坐骨神经痛,主持（4）国家资助博士后研究人员计划（C档）,当归四逆汤抑制CCI大鼠坐骨神经巨噬细胞-施万细胞串扰治疗坐骨神经痛, 主持（5）中国博士后科学基金特别资助,当归四逆汤调控巨噬细胞-神经元串扰抑制外周敏化缓解坐骨神经痛,主持（6）中国博士后科学基金会博士后面上资助,当归四逆汤调节内皮细胞-施万细胞耦联促进损伤神经修复治疗坐骨神经痛,主持（7）暨南大学中央高校基本科研业务费,当归四逆汤调节 DRG巨噬细胞-神经元串扰缓解外周敏化治疗坐骨神经痛,主持 2.论文：（1）Di, Z.（张迪）; Zhenni, C.; Zifeng, Z.; Bei, J.; Yong, C.; Yixuan, L.; Yuwei, P.; Li, G.; Jiaxu, C.（陈家旭）; Guoping, Z.（赵国平）, Danggui Sini Decoction normalizes the intestinal microbiota and serum metabolite levels to treat sciatica. Phytomedicine 2024, 132, 155740.（第一作者，IF：8.3）（2）.Zhang, D.（张迪）; Jing, B.; Chen, Z.; Li, X.; Shi, H.; Zheng, Y.; Chang, S.; Zhao, G.（赵国平）, Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway. Phytomedicine 2022, 106, 154420. （第一作者，IF：8.3）（3）Si, W.（史惠媚）; Li, X.; Jing, B.; Chang, S.; Zheng, Y.; Chen, Z.; Zhao, G.; Zhang, D.（张迪）, Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF-κB pathway to alleviate neuropathic pain. Phytotherapy research. 2024, 38, (1), 265-279. （共同通讯，IF：6.3）（4）Zhang, D.（张迪）; Chang, S.; Li, X.; Shi, H.; Jing, B.; Chen, Z.; Lin, Y.; Zheng, Y.; Qian, G.; Pan, Y.; Zhao, G. （赵国平）, Therapeutic effect of paeoniflorin on chronic constriction injury of the sciatic nerve via the inhibition of Schwann cell apoptosis. Phytotherapy research 2022, 36, (6), 2572-2582. （第一作者，IF：6.3）（5）Zhang, D.（张迪）; Li, X.; Jing, B.; Chen, Z.; Shi, H.; Zheng, Y.; Chang, S.; Sun, J.; Zhao, G（赵国平）., α-Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair. Phytotherapy research 2023, 37, (1), 151-162. （第一作者，IF：6.3）（6）Si, W.; Chen, Z.; Bei, J.; Chang, S.; Zheng, Y.; Gao, L.; Zhao, G.; Li, X.; Zhang, D.（张迪）, Stigmasterol alleviates neuropathic pain by reducing Schwann cell-macrophage cascade in DRG by modulating IL-34/CSF1R. CNS neuroscience & therapeutics, 2024, 30, (4), e14657. （共同通讯，IF：5.0）（7）Zhang, D.（张迪）; Jing, B.; Chen, Z. N.; Li, X.; Shi, H. M.; Zheng, Y. C.; Chang, S. Q.; Gao, L.; Zhao, G. P. （赵国平）, Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting nerve repair via the TLR4/NF-κB pathway. CNS neuroscience & therapeutics, 2023, 29, (4), 1000-1011. （第一作者，IF：5.0）（8）Jing, B.（景贝）; Zhao, J. J.; Chen, Z. N.; Si, W. M.; Chang, S. Q.; Zheng, Y. C.; Zhuang, Z. F.; Zhao, G. P.; Zhang, D.（张迪）, ( +)-Catechin Alleviates CCI-Induced Neuropathic Pain by Modulating Microglia M1 and M2 Polarization via the TLR4/MyD88/NF-κB Signaling Pathway. Journal of neuroimmune pharmacology 2025, 20, (1), 33. （共同通讯，IF：3.5）（9）Zheng, Y.（郑雅纯）; Zhao, J.; Chang, S.; Zhuang, Z.; Waimei, S.; Li, X.; Chen, Z.; Jing, B.; Zhang, D.（张迪）; Zhao, G. （赵国平）, β-Sitosterol Alleviates Neuropathic Pain by Affect Microglia Polarization through Inhibiting TLR4/NF-κB Signaling Pathway. Journal of neuroimmune pharmacology 2023, 18, (4), 690-703. （共同通讯，IF：3.5）（10）Jing, B.（景贝）; Chen, Z. N.; Si, W. M.; Zhao, J. J.; Zhao, G. P.; Zhang, D.（张迪）, (+)-Catechin Alleviates CCI-Induced Neuropathic Pain in Rats by Modulating the IL34/CSFIR Axis and Attenuating the Schwann Cell-Macrophage Cascade Response in the DRG. Molecular neurobiology 2024, 61, (8), 5027-5041. （共同通讯，IF：4.3）（11）Li, X.（李鑫）; Zhuang, Z.; Hao, Y.; Lin, S.; Gu, J.; Chang, S.; Lan, L.; Zhao, G.; Zhang, D.（张迪）, Paeonol Relieves Chronic Neuropathic Pain by Reducing Communication Between Schwann Cells and Macrophages in the Dorsal Root Ganglia After Injury. International journal of molecular sciences 2025, 26, (9). （共同通讯，IF：4.9）（12）Zhang, D.（张迪）; Yang, B.; Chang, S. Q.; Ma, S. S.; Sun, J. X.; Yi, L.; Li, X.; Shi, H. M.; Jing, B.; Zheng, Y. C.; Zhang, C. L.; Chen, F. G.; Zhao, G. P. （赵国平）, Protective effect of paeoniflorin on H(2)O(2) induced Schwann cells injury based on network pharmacology and experimental validation. Chinese journal of natural medicines 2021, 19, (2), 90-99. （第一作者，IF：4.6）（13）Zhang, D.（张迪）; Chang, S.; Jing, B.; Li, X.; Shi, H.; Zheng, Y.; Lin, Y.; Chen, Z.; Qian, G.; Pan, Y.; Zhao, G. （赵国平）, Reactive Oxygen Species Are Essential for Vasoconstriction upon Cold Exposure. Oxidative medicine and cellular longevity 2021, 2021, 8578452. （第一作者，SCI收录）（14）Jing, B.（景贝）; Chen, Z. N.; Si, W. M.; Zhao, J. J.; Zhao, G. P.; Zhang, D.（张迪）, (+)-Catechin attenuates CCI-induced neuropathic pain in male rats by promoting the Nrf2 antioxidant pathway to inhibit ROS/TLR4/NF-κB-mediated activation of the NLRP3 inflammasome. Journal of neuroscience research 2024, 102, (8), e25372.（共同通讯，IF：3.4）（15）Zhang, D.（张迪）; Sun, J.; Yang, B.; Ma, S.; Zhang, C.; Zhao, G. （赵国平）, Therapeutic Effect of Tetrapanax papyriferus and Hederagenin on Chronic Neuropathic Pain of Chronic Constriction Injury of Sciatic Nerve Rats Based on KEGG Pathway Prediction and Experimental Verification. Evidence-based Complementary and Alternative Medicine 2020, 2020, 2545806. （第一作者，SCI收录）（16）Zhang, D.（张迪）; Li, X.; Jing, B.; Shi, H.; Chang, S.; Chen, Z.; Zheng, Y.; Pan, Y.; Qian, G.; Zhao, G. （赵国平）, Identification of pathways and key genes in male late-stage carotid atherosclerosis using bioinformatics analysis. Experimental and therapeutic medicine 2022, 24, (1), 460. （第一作者，IF：2.3）（17）Zhang, D.（张迪）; Sun, J.; Chang, S.; Li, X.; Shi, H.; Jing, B.; Zheng, Y.; Lin, Y.; Qian, G.; Pan, Y.; Zhao, G. （赵国平）, Protective effect of 18β-glycyrrhetinic acid against H(2)O(2)-induced injury in Schwann cells based on network pharmacology and experimental validation. Experimental"