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Zunsheng Han

北京协和医学院

H指数:8

被引数:135

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Development and Evaluation of a Phospholipid Complex-Loaded SMEDDS for Enhanced Oral Delivery of H007, a Novel Anti-Hyperlipidemic Drug

磷脂复合物负载的SMEDDS用于增强新型抗高脂血症药物H007的口服递送的开发与评价

IF5.5

2026-04-130

OAAI

4-hydroxy-2,5-dihydrothiazole derivatives as a new class of small-molecule antibiotics for MRSA: AI-integrated design, chemical synthesis and biological evaluation

4-羟基-2,5-二氢噻唑类衍生物作为MRSA的一类新型小分子抗生素：AI集成设计、化学合成与生物评价

European Journal of Medicinal Chemistry

IF5.9

2025-10-160

PRE

The state-of-the-art machine learning model for plasma protein binding prediction: Computational modeling with OCHEM and experimental validation

用于血浆蛋白结合预测的最新机器学习模型: 使用OCHEM进行计算建模和实验验证

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2025-01-010

OA

Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-12-010

PRE

Novel pleuromutilin derivatives conjugated with phenyl-sulfide and boron-containing moieties as potent antibacterial agents against antibiotic-resistant bacteria

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-11-010

PRE

Discovery of Oral AMP-Activated Protein Kinase Activators for Treating Hyperlipidemia

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-05-131

PRE

AutoMolDesigner for Antibiotic Discovery: An AI-Based Open-Source Software for Automated Design of Small-Molecule Antibiotics

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-01-244

OA

Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection

ACTA PHARMACEUTICA SINICA B

IF14.6

2023-12-017

OAAI

Discovery of isatin-β-methyldithiocarbazate derivatives as New Delhi metallo- β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-10-011

OAAI

Exploration and Biological Evaluation of 1,3-Diamino-7H-pyrrol[3,2-f]quinazoline Derivatives as Dihydrofolate Reductase Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-09-128

PRE

Discovery of N-quinazolinone-4-hydroxy-2-quinolone-3-carboxamides as DNA gyrase B-targeted antibacterial agents

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2022-06-077

OAAI

A pico-HPLC-LIF system for the amplification-free determination of multiple miRNAs in cells

CHINESE CHEMICAL LETTERS

IF8.9

2021-07-0111

PREAI