Zheng‐Xiong Xi - Publications, H-index & Citations

Zheng-Xiong Xi (Zheng‐Xiong Xi)

university of texas system

57H指数

189论文数

1.0W被引数

收录论文 99

发表时间

Dual-target mu opioid-dopamine D3 receptor (MOR-D3R) ligands based on etonitazene: New leads for transforming nitazenes into novel analgesics 基于依诺硝唑的双靶点μ阿片-多巴胺D3受体(MOR-D3R)配体：将硝唑类化合物转化为新型镇痛药的新先导化合物

European Journal of Medicinal Chemistry

IF5.9

2026-06-01

PREAI

Jahan, Khorshada; Glatfelter, Grant; Sanchez, Julie; Maitland, Alexander D.; Bonifazi, Alessandro; Saab, Elizabeth; Keegan, Bradley M.; Rais, Rana; Bi, Guo-Hua; Gomez, Juan L.; Michaelides, Michael; Xi, Zheng-Xiong; Lane, J. Robert; Canals, Meritxell; Baumann, Michael H.; Newman, Amy Hauck

Cocaine-Induced Immediate-Early Gene Expression in the Nucleus Accumbens: Roles of Separate cAMP Sensors 可卡因诱导的即刻早期基因在核壳体中的表达：独立cAMP传感器的角色

Journal of Neurochemistry

IF4

2026-04-01

PREAI

Zhang, Hai-Ying; Salman, Tabinda; Bi, Guo-Hua; Jiang, Sunny Z.; Gerfen, Charles R.; Lutas, Andrew; Xu, Wenqin; Xi, Zheng-Xiong; Eiden, Lee E.

Brain CB2 receptor: a new target in medication development for treating opioid use disorder in rodents 脑CB2受体：治疗啮齿类动物阿片类药物使用障碍药物开发的新靶点

Molecular Psychiatry

IF10.1

2025-12-11

OAAI

Omar Soler-Cedeño; Hai-Ying Zhang; Emma Xiong; Guo-Hua Bi; Hannah Alton; Maia Maras; Qing-Rong Liu; Pinaki Bhattacharjee; Malliga R. Iyer; Zheng-Xiong Xi

Cannabinoid CB1 receptor and mu-opioid receptor interaction: new insights from conditional knockout mice 大麻素CB1受体和μ-阿片受体相互作用：来自条件性敲除小鼠的新见解

Neuropsychopharmacology

IF7.1

2025-09-25

OAAI

Hannah Alton; Emily Linz; Guo-Hua Bi; Omar Soler-Cedeno; Maia Maras; Zheng-Xiong Xi

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats Troriluzole能减轻大鼠的阿片类药物摄入、强化效果、觅药行为、躯体依赖和镇痛耐受性。

British Journal of Pharmacology

IF7.7

2025-09-23

OAAI

Ewa Galaj; Saadet Inan; Guo-Hua Bi; Sonita Wiah; George Adamson; Allen B. Reitz; Zheng-Xiong Xi; Scott M. Rawls

Presynaptic and Postsynaptic Mesolimbic Dopamine D3 Receptors Play Distinct Roles in Cocaine Versus Opioid Reward in Mice

BIOLOGICAL PSYCHIATRY

IF9

2024-11-01

PREAI

Xi, Zheng-Xiong; Bocarsly, Miriam E.; Galaj, Ewa; Hempel, Briana; Teresi, Catherine; Shaw, Marlisa; Bi, Guo-Hua; Jordan, Chloe; Linz, Emily; Alton, Hannah; Tanda, Gianluigi; Freyberg, Zachary; Alvarez, Veronica A.; Newman, Amy Hauck

AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects

NEUROPSYCHOPHARMACOLOGY

IF7.1

2024-04-10

OAAI

Soler-Cedeno, Omar; Alton, Hannah; Bi, Guo-Hua; Linz, Emily; Ji, Lipin; Makriyannis, Alexandros; Xi, Zheng-Xiong

The selective D3Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats

NEUROPSYCHOPHARMACOLOGY

IF7.1

2024-04-06

OAAI

Panayi, Marios C.; Shetty, Shohan; Porod, Micaela; Bahena, Lisette; Xi, Zheng-Xiong; Newman, Amy Hauck; Schoenbaum, Geoffrey

GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice

TRANSLATIONAL PSYCHIATRY

IF6.2

2024-02-19

OAAI

He, Yi; Shen, Hui; Bi, Guo-Hua; Zhang, Hai-Ying; Soler-Cedeno, Omar; Alton, Hannah; Yang, Yihong; Xi, Zheng-Xiong

Modifications to 1-(4-(2-Bis(4-fluorophenyl)methyl)sulfinyl)alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-12-20

PREAI

Okorom, Amarachi V.; Camacho-Hernandez, Gisela Andrea; Salomon, Kristine; Lee, Kuo Hao; Ku, Therese C.; Cao, Jianjing; Won, Sung Joon; Friedman, Jacob; Lam, Jenny; Paule, James; Rais, Rana; Klein, Benjamin; Xi, Zheng-Xiong; Shi, Lei; Loland, Claus J.; Newman, Amy Hauck

PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice

MOLECULAR PSYCHIATRY

IF10.1

2023-07-21

OAAI

Hempel, Briana; Crissman, Madeline; Pari, Sruti; Klein, Benjamin; Bi, Guo-Hua; Alton, Hannah; Xi, Zheng-Xiong

Dopamine D3/D2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders 基于Cariprazine的多巴胺D3/D2受体配体用于治疗可能被双重诊断为情感障碍的精神兴奋剂使用障碍

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-01-20

OAAI

Gogarnoiu, Emma S.; Vogt, Caleb D.; Sanchez, Julie; Bonifazi, Alessandro; Saab, Elizabeth; Shaik, Anver Basha; Soler-Cedeno, Omar; Bi, Guo-Hua; Klein, Benjamin; Xi, Zheng-Xiong; Lane, J. Robert; Newman, Amy Hauck

Pharmacological targeting of G protein-coupled receptor heteromers

PHARMACOLOGICAL RESEARCH

IF10.5

2022-11-01

OAAI

Moreno, Estefania; Casajuana-Martin, Nil; Coyle, Michael; Campos, Baruc Campos; Galaj, Ewa; del Torrent, Claudia Llinas; Seyedian, Arta; Rea, William; Cai, Ning-Sheng; Bonifazi, Alessandro; Floran, Benjamin; Xi, Zheng-Xiong; Guitart, Xavier; Casado, Vicent; Newman, Amy H.; Bishop, Christopher; Pardo, Leonardo; Ferre, Sergi

Neutral CB1 Receptor Antagonists as Pharmacotherapies for Substance Use Disorders: Rationale, Evidence, and Challenge

CELLS

IF5.2

2022-10-17

OAAI

Soler-Cedeno, Omar; Xi, Zheng-Xiong

A red nucleus-VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use

SCIENCE ADVANCES

IF12.5

2022-09-02

OAAI

He, Yi; Madeo, Graziella; Liang, Ying; Zhang, Cindy; Hempel, Briana; Liu, Xiaojie; Mu, Lianwei; Liu, Shui; Bi, Guo-Hua; Galaj, Ewa; Zhang, Hai-Ying; Shen, Hui; McDevitt, Ross A.; Gardner, Eliot L.; Liu, Qing-Song; Xi, Zheng-Xiong

A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder

NEUROPSYCHOPHARMACOLOGY

IF7.1

2022-07-25

OAAI

Galaj, Ewa; Bi, Guo-Hua; Klein, Benjamin; Hempel, Briana; Shaik, Anver Basha; Gogarnoiu, Emma S.; Friedman, Jacob; Lam, Jenny; Rais, Rana; Reed, John F.; Bloom, Shelley H.; Swanson, Tracy L.; Schmachtenberg, Jennifer L.; Eshleman, Amy J.; Janowsky, Aaron; Xi, Zheng-Xiong; Newman, Amy Hauck

Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research

TRANSLATIONAL PSYCHIATRY

IF6.2

2022-07-18

OAAI

Galaj, Ewa; Hempel, Briana; Moore, Allamar; Klein, Benjamin; Bi, Guo-Hua; Gardner, Eliot L.; Seltzman, Herbert H.; Xi, Zheng-Xiong

Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches

MOLECULAR PSYCHIATRY

IF10.1

2022-01-21

OAAI

You, Zhi-Bing; Gardner, Eliot L.; Galaj, Ewa; Moore, Allamar R.; Buck, Tristram; Jordan, Chloe J.; Humburg, Bree A.; Bi, Guo-Hua; Xi, Zheng-Xiong; Leggio, Lorenzo

Identification of the Risk Genes Associated With Vulnerability to Addiction: Major Findings From Transgenic Animals

FRONTIERS IN NEUROSCIENCE

IF3.2

2022-01-12

OAAI

Jordan, Chloe J.; Xi, Zheng-Xiong

Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors

NEUROPSYCHOPHARMACOLOGY

IF7.1

2021-12-18

OAAI

You, Zhi-Bing; Galaj, Ewa; Alen, Francisco; Wang, Bin; Bi, Guo-Hua; Moore, Allamar R.; Buck, Tristram; Crissman, Madeline; Pari, Sruti; Xi, Zheng-Xiong; Leggio, Lorenzo; Wise, Roy A.; Gardner, Eliot L.

研究方向