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T

Taha Y. Taha

gladstone institutes
H指数:15
被引数:2,047

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Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern

用于识别来自流行病相关病毒解旋酶抑制剂的药物重用筛选

SLAS Discovery
IF2.7
2026-04-290
OAAI
Nicole L. Inniss; Margarita Rzhetskaya; Ryan P. Kich; Elizabeth Gleason; Taha Y. Taha; Francisco J. Zapatero-Belinchón; Julia Rosecrans; Valentina Pedrero-Classen; Kenneth Huang; Gilles Degotte; Luca Lizzadro; Jason Pattie; Adam R. Renslo; George Minasov; Melanie Ott; Kelly E.R. Bachta; Karla J.F. Satchell; Judd F. Hultquist
Discovery of Coronavirus Main Protease Inhibitors with Enhanced Brain Exposure and Potent Oral Efficacy in SARS-CoV-2 and MERS Infection Models
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2026-01-010
PRE
Lizzadro, Luca; Li, Jiapeng; Taha, Taha Y.; Degotte, Gilles; Detomasi, Tyler C.; Zapatero-Belinchon, Francisco J.; Hantz, Eric R.; Huang, Sijie; Matsui, Yusuke; Henderson, Will R.; McCann, Jack T.; Montano, Mauricio; Rosecrans, Julia; Torres Pomares, Daniel F.; McGovern, Briana L.; Diaz-Tapia, Randy; Benjamin, Jared; Gordon, Mary E.; Suazo, Isidora D.; Settineri, Nicholas S.; Diallo, Amy; Krogan, Nevan J.; Shoichet, Brian K.; Verba, Kliment A.; Albrecht, Randy; Garcia-Sastre, Adolfo; White, Kris M.; Ott, Melanie; Craik, Charles S.; Renslo, Adam R.
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

SARS-CoV-2 Omicron XEC株中一种非刺突核衣壳R204P突变增强了炎症和致病性

Nature Communications
IF15.7
2025-12-140
OAAI
Shuhei Tsujino; Masumi Tsuda; Sayaka Deguchi; Jumpei Ito; Taha Y. Taha; Hesham Nasser; Lei Wang; Julia Rosecrans; Rigel Suzuki; Saori Suzuki; Kumiko Yoshimatsu; Melanie Ott; Terumasa Ikeda; Kei Sato; Kazuo Takayama; Shinya Tanaka; Tomokazu Tamura; Takasuke Fukuhara
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy In Vivo
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-12-010
PRE
Jaishankar, Priyadarshini; Correy, Galen J.; Matsui, Yusuke; Togo, Takaya; Rachman, Moira M.; Stevens, Maisie G. V.; Hantz, Eric R.; Zheng, Jeffrey; Diolaiti, Morgan E.; Montano, Mauricio; Taha, Taha Y.; Rosecrans, Julia; Pampel, Julius; Krogan, Nevan J.; Shoichet, Brian K.; Ashworth, Alan; Ott, Melanie; Fraser, James S.; Renslo, Adam R.
The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2

Mac1 ADP-核糖基水解酶是SARS-CoV-2的 therapeutic target。

ELIFE
IF0
2025-11-191
OA
Suryawanshi, Rahul K.; Jaishankar, Priyadarshini; Correy, Galen J.; Rachman, Moira M.; O'leary, Patrick C.; Taha, Taha Y.; Matsui, Yusuke; Zapatero-Belinchon, Francisco J.; Mccavitt-Malvido, Maria; Doruk, Yagmur U.; Stevens, Maisie Gv; Diolaiti, Morgan E.; Jogalekar, Manasi P.; Chen, Huadong; Richards, Alicia L.; Kongpracha, Pornparn; Bali, Sofia; Montano, Mauricio; Rosecrans, Julia; Matthay, Michael; Togo, Takaya; Gonciarz, Ryan L.; Gopalkrishnan, Saumya; Neitz, R. Jeffrey; Krogan, Nevan J.; Swaney, Danielle L.; Shoichet, Brian K.; Ott, Melanie; Renslo, Adam R.; Ashworth, Alan; Fraser, James S.
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy

基于结构的具有高生物利用度、共价键、广谱冠状病毒MPro抑制剂的发现，并具有强体内效力

SCIENCE ADVANCES
IF12.5
2025-04-250
OA
Detomasi, Tyler C.; Degotte, Gilles; Huang, Sijie; Suryawanshi, Rahul K.; Diallo, Amy; Lizzadro, Luca; Zaptero-Belinchon, Francisco J.; Taha, Taha Y.; Li, Jiapeng; Richards, Alicia L.; Hantz, Eric R.; Alam, Zain; Montano, Mauricio; McCavitt-Malvido, Maria; Gumpena, Rajesh; Partridge, James R.; Correy, Galen J.; Matsui, Yusuke; Charvat, Annemarie F.; Glenn, Isabella S.; Rosecrans, Julia; Revalde, Jezrael L.; Anderson, Dashiell; Hultquist, Judd F.; Arkin, Michelle R.; Neitz, R. Jeffrey; Swaney, Danielle L.; Krogan, Nevan J.; Shoichet, Brian K.; Verba, Kliment A.; Ott, Melanie; Renslo, Adam R.; Craik, Charles S.
Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6
PLOS PATHOGENS
IF4.9
2025-03-010
OAAI
Taha, Taha Y.; Ezzatpour, Shahrzad; Hayashi, Jennifer M.; Ye, Chengjin; Zapatero-Belinchon, Francisco J.; Rosecrans, Julia A.; Kimmerly, Gabriella R.; Chen, Irene P.; Walcott, Keith; Kurianowicz, Anna; Jorgens, Danielle M.; Chaplin, Natalie R.; Choi, Annette; Buchholz, David W.; Sahler, Julie; Hilt, Zachary T.; Imbiakha, Brian; Vagi-Szmola, Cecilia; Montano, Mauricio; Stevenson, Erica; Gordon, Martin; Swaney, Danielle L.; Krogan, Nevan J.; Whittaker, Gary R.; Martinez-Sobrido, Luis; Aguilar, Hector C.; Ott, Melanie
Torsional twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

SARS-CoV和SARS-CoV-2 SUD-N和SUD-M结构域的扭转扭曲

PROTEIN SCIENCE
IF5.2
2025-02-190
OAAI
Rosas-Lemus, Monica; Minasov, George; Brunzelle, Joseph S.; Taha, Taha Y.; Lemak, Sofia; Yin, Shaohui; Shuvalova, Ludmilla; Rosecrans, Julia; Khanna, Kanika; Seifert, H. Steven; Savchenko, Alexei; Stogios, Peter J.; Ott, Melanie; Satchell, Karla J. F.
Fibrin drives thromboinflammation and neuropathology in COVID-19
Nature
IF48.5
2024-08-280
OAAI
Jae Kyu Ryu; Zhaoqi Yan; Mauricio Montano; Elif G. Sozmen; Karuna Dixit; Rahul K. Suryawanshi; Yusuke Matsui; Ekram Helmy; Prashant Kaushal; Sara K. Makanani; Thomas J. Deerinck; Anke Meyer-Franke; Pamela E. Rios Coronado; Troy N. Trevino; Min-Gyoung Shin; Reshmi Tognatta; Yixin Liu; Renaud Schuck; Lucas Le; Hisao Miyajima; Andrew S. Mendiola; Nikhita Arun; Brandon Guo; Taha Y. Taha; Ayushi Agrawal; Eilidh MacDonald; Oliver Aries; Aaron Yan; Olivia Weaver; Mark A. Petersen; Rosa Meza Acevedo; Maria del Pilar S. Alzamora; Reuben Thomas; Michela Traglia; Valentina L. Kouznetsova; Igor F. Tsigelny; Alexander R. Pico; Kristy Red-Horse; Mark H. Ellisman; Nevan J. Krogan; Mehdi Bouhaddou; Melanie Ott; Warner C. Greene; Katerina Akassoglou
Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy
NPJ VACCINES
IF6.5
2024-08-270
OAAI
Li, Lin; Matsui, Yusuke; Prahl, Mary K.; Cassidy, Arianna G.; Golan, Yarden; Jigmeddagva, Unurzul; Ozarslan, Nida; Lin, Christine Y.; Buarpung, Sirirak; Gonzalez, Veronica J.; Chidboy, Megan A.; Basilio, Emilia; Lynch, Kara L.; Song, Dongli; Jegatheesan, Priya; Rai, Daljeet S.; Govindaswami, Balaji; Needens, Jordan; Rincon, Monica; Myatt, Leslie; Taha, Taha Y.; Montano, Mauricio; Ott, Melanie; Greene, Warner C.; Gaw, Stephanie L.
NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids
SCIENTIFIC REPORTS
IF3.9
2024-07-041
OAAI
Simoneau, Camille R.; Chen, Pei-Yi; Xing, Galen K.; Hayashi, Jennifer M.; Chen, Irene P.; Khalid, Mir M.; Meyers, Nathan L.; Taha, Taha Y.; Leon, Kristoffer E.; Suryawanshi, Rahul K.; McCavitt-Malvido, Maria; Ashuach, Tal; Fontaine, Krystal A.; Rodriguez, Lauren; Joehnk, Bastian; Walcott, Keith; Vasudevan, Sreelakshmi; Fang, Xiaohui; Maishan, Mazharul; Schultz, Shawn; Roose, Jeroen P.; Matthay, Michael A.; Sil, Anita; Arjomandi, Mehrdad; Yosef, Nir; Ott, Melanie
Hepatitis C virus infects and perturbs liver stem cells
MBIO
IF4.7
2023-12-195
OAAI
Meyers, Nathan L.; Ashuach, Tal; Lyons, Danielle E.; Khalid, Mir M.; Simoneau, Camille R.; Erickson, Ann L.; Bouhaddou, Mehdi; Nguyen, Thong T.; Kumar, G. Renuka; Taha, Taha Y.; Natarajan, Vaishaali; Baron, Jody L.; Neff, Norma; Zanini, Fabio; Mahmoudi, Tokameh; Quake, Stephen R.; Krogan, Nevan J.; Cooper, Stewart; Mcdevitt, Todd C.; Yosef, Nir; Ott, Melanie
Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination
EMERGING MICROBES & INFECTIONS
IF7.5
2023-10-311
OAAI
Suryawanshi, Rahul K.; Taha, Taha Y.; McCavitt-Malvido, Maria; Silva, Ines; Khalid, Mir M.; Syed, Abdullah M.; Chen, Irene P.; Saldhi, Prachi; Sreekumar, Bharath; Montano, Mauricio; Foresythe, Kafaya; Tabata, Takako; Kumar, G. Renuka; Sotomayor-Gonzalez, Alicia; Servellita, Venice; Gliwa, Amelia; Nguyen, Jenny; Kojima, Noah; Arellanor, Teresa; Bussanich, Aallyah; Hess, Victoria; Shacreaw, Maria; Lopez, Lauren; Brobeck, Matthew; Turner, Fred; Wang, Yuzhu; Ghazarian, Sydney; Davis, Gregg; Rodriguez, Diviana; Doudna, Jennifer; Spraggon, Lee; Chiu, Charles Y.; Ott, Melanie
SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants
STEM CELL REPORTS
IF5.1
2023-03-013
OAAI
Hysenaj, Lisiena; Little, Samantha; Kulhanek, Kayla; Magnen, Melia; Bahl, Kriti; Gbenedio, Oghenekevwe M.; Prinz, Morgan; Rodriguez, Lauren; Andersen, Christopher; Rao, Arjun Arkal; Shen, Alan; Lone, Jean-Christophe; Lupin-Jimenez, Leonard C.; Bonser, Luke R.; Serwas, Nina K.; Mick, Eran; Khalid, Mir M.; Taha, Taha Y.; Kumar, Renuka; Li, Jack Z.; Ding, Vivianne W.; Matsumoto, Shotaro; Maishan, Mazharul; Sreekumar, Bharath; Simoneau, Camille; Nazarenko, Irina; Tomlinson, Michael G.; Khan, Khajida; von Gottberg, Anne; Sigal, Alex; Looney, Mark R.; Fragiadakis, Gabriela K.; Jablons, David M.; Langelier, Charles R.; Matthay, Michael; Krummel, Matthew; Erle, David J.; Combes, Alexis J.; Sil, Anita; Ott, Melanie; Kratz, Johannes R.; Roose, Jeroen P.

研究方向

暂未获取到该数据
M
Mélanie Ott
H 指数:74论文数:316被引数:2.6万
M
Mauricio Montaño
H 指数:24论文数:75被引数:2,094
M
Mir M. Khalid
H 指数:20论文数:61被引数:3,403
I
Irene P. Chen
H 指数:16论文数:44被引数:1,523
N
Nevan J. Krogan
H 指数:129论文数:759被引数:6.9万
Y
Yusuke Matsui
H 指数:16论文数:111被引数:798
J
Julia Rosecrans
H 指数:4论文数:21被引数:45
B
Bharath Sreekumar
H 指数:20论文数:56被引数:2,535
J
Jennifer M. Hayashi
H 指数:16论文数:37被引数:2,197
P
Pavel A. Petukhov
H 指数:31论文数:119被引数:2,767