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H

Heather C. Denroche

department of surgery

H指数:18

被引数:1,183

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Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice

胰岛淀粉样蛋白破坏MHC class II抗原呈递并延缓NOD小鼠的自身免疫性糖尿病

IF10.2

2025-12-220

OAAI

A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models

NATURE COMMUNICATIONS

IF15.7

2023-10-098

OAAI

T cells accumulate in non-diabetic islets during ageing

IMMUNITY & AGEING

IF5.6

2021-02-2313

OAAI

AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects

SCIENTIFIC REPORTS

IF3.9

2020-06-2914

OAAI

IAPP and type 1 diabetes: implications for immunity, metabolism and islet transplants

JOURNAL OF MOLECULAR ENDOCRINOLOGY

IF3.8

2018-02-0146

OAAI

When beta cells talk back

IF10.2

2017-09-204

OAAI

The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapy

MOLECULAR METABOLISM

IF6.6

2016-08-0111

OAAI

Disrupted Leptin Signaling in the Lateral Hypothalamus and Ventral Premammillary Nucleus Alters Insulin and Glucagon Secretion and Protects Against Diet-Induced Obesity

IF3.3

2016-05-1614

OAAI

Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-04-0139

OAAI

Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy

IF3.3

2015-12-2220

OA

Amyloid Formation in Human Islets Is Enhanced by Heparin and Inhibited by Heparinase

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2015-06-0128

OAAI

IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+ T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance

JOURNAL OF IMMUNOLOGY

IF3.4

2015-05-15160

OAAI

Leptin induces fasting hypoglycaemia in a mouse model of diabetes through the depletion of glycerol

IF10.2

2015-02-2617

OAAI

IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice

IL-1介导人胰岛淀粉样多肽转基因小鼠中淀粉样蛋白相关的胰岛功能障碍和炎症

IF10.2

2014-12-1072

OAAI

Leptin Administration Enhances Islet Transplant Performance in Diabetic Mice

IF7.5

2013-07-1712

OAAI

Circulating miR-375 as a Biomarker of β-Cell Death and Diabetes in Mice

IF3.3

2013-01-14162

OA

The role of leptin in glucose homeostasis

瘦素在葡萄糖稳态中的作用

JOURNAL OF DIABETES INVESTIGATION

IF3

2012-03-28129

OAAI

Hepatic leptin signalling and subdiaphragmatic vagal efferents are not required for leptin-induced increases of plasma IGF binding protein-2 (IGFBP-2) in ob/ob mice

IF10.2

2011-12-2823

OA

Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling

IF7.5

2011-04-2398

OAAI

Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance

IF7.5

2010-09-2866

OAAI