未登录 Discovery and Early Optimization of 1H-Indole-2-carboxamides with Anti-Trypanosoma cruzi Activity 1H-吲哚-2-甲酰胺类化合物的发现及其抗克氏锥虫活性初探 de Oliveira, Ramon G.; Cruz, Luiza R.; Dessoy, Marco A.; Koovits, Paul J.; dos Santos, Deborah A.; de Oliveira, Luiz F. N.; Ferreira, Rafael A.; Mollo, Maria C.; Lee, Eun; Duarte, Simone M.; Krogh, Renata; Ferreira, Leonardo L. G.; Chelucci, Rafael C.; Dichiara, Maria; Simpson, Quillon J.; Feltrin, Clarissa; da Silva, Adriana C.; dos Santos, Benedito M.; Broering, Milena F.; Pollastri, Michael P.; Ferrins, Lori; Moraes, Carolina B.; Andricopulo, Adriano D.; Kratz, Jadel M.; Sjo, Peter; Mowbray, Charles E.; Dias, Luiz C. 分享 收藏
Identification of Substituted 4-Aminocinnolines as Broad-Spectrum Antiparasitic Agents Spaulding, Andrew; Sharma, Amrita; Giardini, Miriam A.; Hoffman, Benjamin; Bernatchez, Jean A.; Mccall, Laura-Isobel; Calvet, Claudia M.; Ackermann, Jasmin; Souza, Julia M.; Thomas, Diane; Millard, Caroline C.; Devine, William G.; Singh, Baljinder; Silva, Everton M.; Leed, Susan E.; Roncal, Norma E.; Penn, Erica C.; Erath, Jessey; Kumar, Gaurav; Sepulveda, Yadira; Garcia, Arnold; Rodriguez, Ana; El-Sakkary, Nelly; Sciotti, Richard J.; Campbell, Robert F.; Momper, Jeremiah D.; Mckerrow, James H.; Caffrey, Conor R.; Siqueira-Neto, Jair L.; Pollastri, Michael P.; Mensa-Wilmot, Kojo; Ferrins, Lori 分享 收藏
Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei Ferrins, Lori; Diaz, Rosario; Cordon-Obras, Carlos; Rojas-Barros, Domingo; Quotadamo, Antonio; Oehme, Daniel P.; Ceballos-Perez, Gloria; Swaminathan, Uma; Perez-Moreno, Guiomar; Bosch-Navarrete, Cristina; Garcia-Hernandez, Raquel; Gomez-Linan, Claudia; Saura, Andreu; Ruiz-Perez, Luis Miguel; Gamarro, Francisco; Martinez-Martinez, Maria Santos; Manzano, Pilar; Gonzalez-Pacanowska, Dolores; Navarro, Miguel; Pollastri, Michael P. 分享 收藏
Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes (vol 14, 1149145, 2023) Ferrins, Lori; Buskes, Melissa J.; Kapteyn, Madison M.; Engels, Hannah N.; Enos, Suzanne E.; Lu, Chenyang; Klug, Dana M.; Singh, Baljinder; Quotadamo, Antonio; Bachovchin, Kelly; Tear, Westley F.; Spaulding, Andrew E.; Forbes, Katherine C.; Bag, Seema; Rivers, Mitch; Leblanc, Catherine; Burchfield, Erin; Armand, Jeremy R.; Diaz-Gonzalez, Rosario; Ceballos-Perez, Gloria; Garcia-Hernandez, Raquel; Perez-Moreno, Guiomar; Bosch-Navarrete, Cristina; Gomez-Linan, Claudia; Ruiz-Perez, Luis Miguel; Gamarro, Francisco; Gonzalez-Pacanowska, Dolores; Navarro, Miguel; Mensa-Wilmot, Kojo; Pollastri, Michael P.; Kyle, Dennis E.; Rice, Christopher A. 分享 收藏
Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis Dichiara, Maria; Simpson, Quillon J.; Quotadamo, Antonio; Jalani, Hitesh B.; Huang, Anson X.; Millard, Caroline C.; Klug, Dana M.; Tse, Edwin G.; Todd, Matthew H.; Silva, Daniel Gedder; Emery, Flavio da Silva; Carlson, J. Eric; Zheng, Shao-Liang; Vleminckx, Margot; Matheeussen, An; Caljon, Guy; Pollastri, Michael P.; Sjo, Peter; Perry, Benjamin; Ferrins, Lori 分享 收藏
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Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery Singh, Baljinder; Sharma, Amrita; Gunaganti, Naresh; Rivers, Mitch; Gadekar, Pradip K.; Greene, Brady; Chichioco, Michael; Sanz-Rodriguez, Carlos E.; Fu, Courtney; LeBlanc, Catherine; Burchfield, Erin; Sharif, Nyle; Hoffman, Benjamin; Kumar, Gaurav; Purmal, Andrei; Mensa-Wilmot, Kojo; Pollastri, Michael P. 分享 收藏
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Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis Klug, Dana M.; Mavrogiannaki, Eftychia M.; Forbes, Katherine C.; Silva, Lisseth; Diaz-Gonzalez, Rosario; Perez-Moreno, Guiomar; Ceballos-Perez, Gloria; Garcia-Hernandez, Raquel; Bosch-Navarrete, Cristina; Cordon-Obras, Carlos; Gomez-Linan, Claudia; Saura, Andreu; Momper, Jeremiah D.; Santos Martinez-Martinez, Maria; Manzano, Pilar; Syed, Ali; El-Sakkary, Nelly; Caffrey, Conor R.; Gamarro, Francisco; Miguel Ruiz-Perez, Luis; Gonzalez Pacanowska, Dolores; Ferrins, Lori; Navarro, Miguel; Pollastri, Michael P. 分享 收藏
Medicinal Chemistry Optimization of a Diaminopurine Chemotype: Toward a Lead for Trypanosoma brucei Inhibitors Singh, Baljinder; Diaz-Gonzalez, Rosario; Ceballos-Perez, Gloria; Rojas-Barros, Domingo I.; Gunaganti, Naresh; Gillingwater, Kirsten; Santos Martinez-Martinez, Maria; Manzano, Pilar; Navarro, Miguel; Pollastri, Michael P. 分享 收藏
Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors Singh, Baljinder; Bernatchez, Jean A.; McCall, Laura-Isobel; Calvet, Claudia M.; Ackermann, Jasmin; Souza, Julia M.; Thomas, Diane; Silva, Everton M.; Bachovchin, Kelly A.; Klug, Dana M.; Jalani, Hitesh B.; Bag, Seema; Buskes, Melissa J.; Leed, Susan E.; Roncal, Norma E.; Penn, Erica C.; Erath, Jessey; Rodriguez, Ana; Sciotti, Richard J.; Campbell, Robert F.; McKerrow, James; Siqueira-Neto, Jair L.; Ferrins, Lori; Pollastri, Michael P. 分享 收藏
Structure-Bioactivity Relationships of Lapatinib Derived Analogs against Schistosoma mansoni Buskes, Melissa J.; Clements, Monica; Bachovchin, Kelly A.; Jalani, Hitesh B.; Leonard, Allison; Bag, Seema; Klug, Dana M.; Singh, Baljinder; Campbell, Robert F.; Sciotti, Richard J.; El-Sakkary, Nelly; Caffrey, Conor R.; Pollastri, Michael P.; Ferrins, Lori 分享 收藏
Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity Klug, Dana M.; Diaz-Gonzalez, Rosario; DeLano, Travis J.; Mavrogiannaki, Eftychia M.; Buskes, Melissa J.; Dalton, Raeann M.; Fisher, John K.; Schneider, Katherine M.; Hilborne, Vivian; Fritsche, Melanie G.; Simpson, Quillon J.; Tear, Westley F.; Devine, William G.; Perez-Moreno, Guiomar; Ceballos-Perez, Gloria; Garcia-Hernandez, Raquel; Bosch-Navarrete, Cristina; Miguel Ruiz-Perez, Luis; Gamarro, Francisco; Gonzalez-Pacanowska, Dolores; Santos Martinez-Martinez, Maria; Manzano-Chinchon, Pilar; Navarro, Miguel; Pollastri, Michael P.; Ferrins, Lori 分享 收藏
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis Tear, Westley F.; Bag, Seema; Diaz-Gonzalez, Rosario; Ceballos-Perez, Gloria; Rojas-Barros, Domingo I.; Cordon-Obras, Carlos; Perez-Moreno, Guiomar; Garcia-Hernandez, Raquel; Santos Martinez-Martinez, Maria; Miguel Ruiz-Perez, Luis; Gamarro, Francisco; Gonzalez Pacanowska, Dolores; Caffrey, Conor R.; Ferrins, Lori; Manzano, Pilar; Navarro, Miguel; Pollastri, Michael P. 分享 收藏
Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics Klug, Dana M.; Tschiegg, Laura; Diaz, Rosario; Rojas-Barros, Domingo; Perez-Moreno, Guiomar; Ceballos, Gloria; Garcia-Hernandez, Raquel; Santos Martinez-Martinez, Maria; Manzano, Pilar; Miguel Ruiz, Luis; Caffrey, Conor R.; Gamarro, Francisco; Gonzalez Pacanowska, Dolores; Ferrins, Lori; Navarro, Miguel; Pollastri, Michael P. 分享 收藏
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents Klug, Dana M.; Diaz-Gonzalez, Rosario; Perez-Moreno, Guiomar; Ceballos-Perez, Gloria; Garcia-Hernandez, Raquel; Gomez-Perez, Veronica; Ruiz-Perez, Luis Miguel; Rojas-Barros, Domingo I.; Gamarro, Francisco; Gonzalez-Pacanowska, Dolores; Martinez-Martinez, Maria S.; Manzano, Pilar; Ferrins, Lori; Caffrey, Conor R.; Navarro, Miguel; Pollastri, Michael P. 分享 收藏
Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development Bachoychin, Kelly A.; Sharma, Amrita; Bag, Seema; Klug, Dana M.; Schneider, Katherine M.; Singh, Baljinder; Jalani, Hitesh B.; Buskes, Melissa J.; Mehta, Naimee; Tanghe, Scott; Momper, Jeremiah D.; Sciotti, Richard J.; Rodriguez, Ana; Mensa-Wilmot, Kojo; Pollastri, Michael P.; Ferrins, Lori 分享 收藏
Anilinoquinoline based inhibitors of trypanosomatid proliferation Ferrins, Lori; Sharma, Amrita; Thomas, Sarah M.; Mehta, Naimee; Erath, Jessey; Tanghe, Scott; Leed, Susan E.; Rodriguez, Ana; Mensa-Wilmot, Kojo; Sciotti, Richard J.; Gillingwater, Kirsten; Pollastri, Michael P. 分享 收藏
Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation Woodring, Jennifer L.; Behera, Ranjan; Sharma, Amrita; Wiedeman, Justin; Patel, Gautam; Singh, Baljinder; Guyett, Paul; Amata, Emanuele; Erath, Jessey; Roncal, Norma; Penn, Erica; Leed, Susan E.; Rodriguez, Ana; Sciotti, Richard J.; Mensa-Wilmot, Kojo; Pollastri, Michael P. 分享 收藏
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