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G

Gavin W. Collie

AstraZeneca
H指数:23
被引数:2,614

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Correction to “Targeting the Interaction of NRF2 and β-TrCP with Molecular Glues”

对“靶向NRF2和β-TrCP相互作用的分子胶”的更正

ACS Chemical Biology
IF3.8
2026-05-270
PRE
Daniel H. O Donovan; Jon Winter-Holt; Gavin W. Collie; Maria E. Cuomo; David John McGarry; Millie Fox; Bo Kyung Alex Seong; Ursula Grazini; Peter Barton; David Longmire; Andrew Lister; Yong Xu; Hazel Mak; Evelyne J. Barrey; Marta Acebrón-García-de-Eulate; Magdalena Richter; Nisha Peter; Maxime Couturier; Gustavo J. Gutierrez; Ryan Guilbert; Wankyu Lee; Pamela A. Lochhead; Argyrides Argyrou
A dihydrouracil CRBN ligand mitigates IMiD associated safety liabilities in heterobifunctional targeted protein degrader

二氢尿嘧啶CRBN配体减轻了异双功能靶向蛋白降解物中IMiD相关的安全责任

Nature Communications
IF15.7
2026-03-250
OAAI
Monica C. Rodrigo-Brenni; Jasper C. Komen; Ghaith M. Hamza; Natacha Bohin; Tomas Adomavicius; Angelo Andres; Stefan Blaho; Ulf Börjesson; Gavin W. Collie; Gian Marco De Donatis; Frederik Eisele; Ning Gao; Andrea Gohlke; Christoph Grebner; Frida Gustafsson; Andreas Hock; Cecilia Kankkonen; Praveen Kumar; Emilyanne Leonard; Xin Li; Ruth Macdonald; Katja Madeyski-Bengtson; Eric Miele; Philip Nevin; Jeroen Overman; Fiona Pachl; Claudio Pathe; Matthew W. D. Perry; Christopher Phillips; Andy Pike; Ian Purvis; Timothy Rasmusson; Sophie Regan; Linda Reilly; Jonathan Rose; R. Ian Storer; Jingwen Wang; Xiang Zhai; Iacovos N. Michaelides; Kevin Moreau
Discovery and Characterization of Diverse Non-nucleotide Inhibitors of DNPH1 Using an Integrated Hit Finding Strategy
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2025-12-010
PRE
Whitehurst, Benjamin C.; Anderson, Niall A.; Argyrou, Argyrides; Astles, Peter; Barlaam, Bernard; Cadogan, Elaine B.; Carlino, Luca; Collie, Gavin W.; Edwards, Alex; Kitching, Linda; Li, Yaqin; Milbradt, Alexander G.; Nikkila, Jenni; Northall, Sarah; Pahlen, Sara; Patel, Saleha; Savory, Wendy; Schade, Markus; Spencer, Jonathan A.; Stead, Darren; Stubbs, Christopher J.; Wang, Aquan; Wang, Wenxin
Discovery and Optimization of a Non-Nucleoside-Based Series of Inhibitors of 2′-Deoxynucleoside 5′-Monophosphate Glycosidase (DNPH1)

发现和优化一类非核苷类2′-脱氧核苷-5′-单磷酸糖苷酶（DNPH1）抑制剂

Journal of Medicinal Chemistry
IF6.8
2025-11-060
PRE
Bernard Barlaam; Luz Alonso-Crisostomo; Niall A. Anderson; Argyrides Argyrou; Peter C. Astles; Elaine B. Cadogan; Luca Carlino; Gavin W. Collie; Nichola L. Davies; James Hall; Linda Kitching; Xianxi Li; Filippos Michopoulos; Alexander G. Milbradt; Jenni Nikkilä; Sarah Northall; Mark J. O’Connor; Xiaohiu Pei; Joseph Shaw; Danial Slade; Harriet Southgate; Darren Stead; Christopher J. Stubbs; Benjamin C. Whitehurst; Bin Xing; Yihao Yuan; Jie Zhou
Fragment-Based Discovery of Novel MUS81 Inhibitors

基于片段的新型MUS81抑制剂的发现

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2024-06-070
OAAI
Collie, Gavin W.; Borjesson, Ulf; Chen, Yunhua; Dong, Zhiqiang; Di Fruscia, Paolo; Gohlke, Andrea; Hoyle, Anna; Hunt, Thomas A.; Jesani, Mehul H.; Luo, Haiou; Luptak, Jakub; Milbradt, Alexander G.; Narasimhan, Priyanka; Packer, Martin; Patel, Saleha; Qiao, Jingchuan; Storer, R. Ian; Stubbs, Christopher J.; Tart, Jonathan; Truman, Caroline; Wang, Anderson T.; Wheeler, Matthew G.; Winter-Holt, Jon
Identification of Novel Potent NSD2-PWWP1 Ligands Using Structure-Based Design and Computational Approaches
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-05-154
PRE
Carlino, Luca; Astles, Peter C.; Ackroyd, Bryony; Ahmed, Afshan; Chan, Christina; Collie, Gavin W.; Dale, Ian L.; O'Donovan, Daniel H.; Fawcett, Caroline; di Fruscia, Paolo; Gohlke, Andrea; Guo, Xiaoxiao; Hao-Ru Hsu, Jessie; Kaplan, Bethany; Milbradt, Alexander G.; Northall, Sarah; Petrovic, Dusan; Rivers, Emma L.; Underwood, Elizabeth; Webb, Alice
Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-06-218
OAAI
Michaelides, Iacovos N.; Collie, Gavin W.; Borjesson, Ulf; Vasalou, Christina; Alkhatib, Omar; Barlind, Louise; Cheung, Tony; Dale, Ian L.; Embrey, Kevin J.; Hennessy, Edward J.; Khurana, Puneet; Koh, Cheryl M.; Lamb, Michelle L.; Liu, Jianming; Moss, Thomas A.; O'Neill, Daniel J.; Phillips, Christopher; Shaw, Joseph; Snijder, Arjan; Storer, R. Ian; Stubbs, Christopher J.; Han, Fujin; Li, Chengzhi; Qiao, Jingchuan; Sun, Dong-Qing; Wang, Jingwen; Wang, Peng; Yang, Wenzhen
Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays
SCIENTIFIC REPORTS
IF3.9
2022-11-037
OAAI
Pierrat, Olivier A.; Liu, Manjuan; Collie, Gavin W.; Shetty, Kartika; Rodrigues, Matthew J.; Le Bihan, Yann-Vai; Gunnell, Emma A.; McAndrew, P. Craig; Stubbs, Mark; Rowlands, Martin G.; Yahya, Norhakim; Shehu, Erald; Talbot, Rachel; Pickard, Lisa; Bellenie, Benjamin R.; Cheung, Kwai-Ming J.; Drouin, Ludovic; Innocenti, Paolo; Woodward, Hannah; Davis, Owen A.; Lloyd, Matthew G.; Varela, Ana; Huckvale, Rosemary; Broccatelli, Fabio; Carter, Michael; Galiwango, David; Hayes, Angela; Raynaud, Florence, I; Bryant, Christopher; Whittaker, Steven; Rossanese, Olivia W.; Hoelder, Swen; Burke, Rosemary; van Montfort, Rob L. M.
Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-06-0311
OAAI
Davis, Owen A.; Cheung, Kwai-Ming J.; Brennan, Alfie; Lloyd, Matthew G.; Rodrigues, Matthew J.; Pierrat, Olivier A.; Collie, Gavin W.; Le Bihan, Yann-Vai; Huckvale, Rosemary; Harnden, Alice C.; Varela, Ana; Bright, Michael D.; Eve, Paul; Hayes, Angela; Henley, Alan T.; Carter, Michael D.; McAndrew, P. Craig; Talbot, Rachel; Burke, Rosemary; van Montfort, Rob L. M.; Raynaud, Florence, I; Rossanese, Olivia W.; Meniconi, Mirco; Bellenie, Benjamin R.; Hoelder, Swen
Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-11-3010
OAAI
Lloyd, Matthew G.; Huckvale, Rosemary; Cheung, Kwai-Ming J.; Rodrigues, Matthew J.; Collie, Gavin W.; Pierrat, Olivier A.; Iou, Mahad Gatti; Carter, Michael; Davis, Owen A.; McAndrew, P. Craig; Gunnell, Emma; Le Bihan, Yann-Vai; Talbot, Rachel; Henley, Alan T.; Johnson, Louise D.; Hayes, Angela; Bright, Michael D.; Raynaud, Florence, I; Meniconi, Mirco; Burke, Rosemary; van Montfort, Rob L. M.; Rossanese, Olivia W.; Bellenie, Benjamin R.; Hoelder, Swen

研究方向

暂未获取到该数据
S
Stephen Neidle
H 指数:101论文数:791被引数:3.9万
G
Gilles Guichard
H 指数:46论文数:510被引数:7,808
G
Gary N. Parkinson
H 指数:46论文数:158被引数:1.3万
K
Karolina Pulka‐Ziach
H 指数:13论文数:87被引数:653
C
Christopher J. Stubbs
H 指数:18论文数:66被引数:1,153
V
Valérie Gabelica
H 指数:60论文数:301被引数:9,345
A
Anthony P. Reszka
H 指数:31论文数:70被引数:5,180
C
Cameron D. Mackereth
H 指数:27论文数:148被引数:2,713
I
Iacovos N. Michaelides
H 指数:14论文数:32被引数:1,129
F
Frédéric Rosu
H 指数:40论文数:176被引数:5,316