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A

Arie Zask

Columbia University
H指数:39
被引数:4,444

个人简介

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教育背景

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工作经历

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荣誉奖项

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Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19
NATURE COMMUNICATIONS
IF15.7
2022-04-0748
OAAI
Liu, Hengrui; Iketani, Sho; Zask, Arie; Khanizeman, Nisha; Bednarova, Eva; Forouhar, Farhad; Fowler, Brandon; Hong, Seo Jung; Mohri, Hiroshi; Nair, Manoj S.; Huang, Yaoxing; Tay, Nicholas E. S.; Lee, Sumin; Karan, Charles; Resnick, Samuel J.; Quinn, Colette; Li, Wenjing; Shion, Henry; Xia, Xin; Daniels, Jacob D.; Bartolo-Cruz, Michelle; Farina, Marcelo; Rajbhandari, Presha; Jurtschenko, Christopher; Lauber, Matthew A.; McDonald, Thomas; Stokes, Michael E.; Hurst, Brett L.; Rovis, Tomislav; Chavez, Alejandro; Ho, David D.; Stockwell, Brent R.
Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2
CANCER RESEARCH
IF16.6
2010-01-13203
OAAI
Yu, Ker; Shi, Celine; Toral-Barza, Lourdes; Lucas, Judy; Shor, Boris; Kim, Jae Eun; Zhang, Wei-Guo; Mahoney, Robert; Gaydos, Christine; Tardio, LuAnna; Kim, Sung Kyoo; Conant, Roger; Curran, Kevin; Kaplan, Joshua; Verheijen, Jeroen; Ayral-Kaloustian, Semiramis; Mansour, Tarek S.; Abraham, Robert T.; Zask, Arie; Gibbons, James J.
Discovery of 4-Morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as Highly Potent and Selective ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin (mTOR): Optimization of the 6-Aryl Substituent
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2009-11-0662
PREAI
Verheijen, Jeroen C.; Richard, David J.; Curran, Kevin; Kaplan, Joshua; Lefever, Mark; Nowak, Pawel; Malwitz, David J.; Brooijmans, Natasja; Toral-Barza, Lourdes; Zhang, Wei-Guo; Lucas, Judy; Hollander, Irwin; Ayral-Kaloustian, Semiramis; Mansour, Tarek S.; Yu, Ker; Zask, Arie
ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2009-07-31111
PREAI
Zask, Arie; Verheijen, Jeroen C.; Curran, Kevin; Kaplan, Joshua; Richard, David J.; Nowak, Pawel; Malwitz, David J.; Brooijmans, Natasja; Bard, Joel; Svenson, Kristine; Lucas, Judy; Toral-Barza, Lourdes; Zhang, Wei-Guo; Hollander, Irwin; Gibbons, James J.; Abraham, Robert R.; Ayral-Kaloustian, Semiramis; Mansour, Tarek S.; Yu, Ker
Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

哺乳动物雷帕霉素靶标的新型ATP竞争性和选择性抑制剂的生化，细胞和体内活性

CANCER RESEARCH
IF16.6
2009-07-29354
OAAI
Yu, Ker; Toral-Barza, Lourdes; Shi, Celine; Zhang, Wei-Guo; Lucas, Judy; Shor, Boris; Kim, Jamie; Verheijen, Jeroen; Curran, Kevin; Malwitz, David J.; Cole, Derek C.; Ellingboe, John; Ayral-Kaloustian, Semiramis; Mansour, Tarek S.; Gibbons, James J.; Abraham, Robert T.; Nowak, Pawel; Zask, Arie
Discovery of 4-(Benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(Pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2009-03-2478
PREAI
Tsou, Hwei-Ru; Liu, Xiaoxiang; Birnberg, Gary; Kaplan, Joshua; Otteng, Mercy; Tran, Tritin; Kutterer, Kristina; Tang, Zhilian; Suayan, Ron; Zask, Arie; Ravi, Malini; Bretz, Angela; Grillo, Mary; McGinnis, John P.; Rabindran, Sridhar K.; Ayral-Kaloustian, Semiramis; Mansour, Tarek S.

研究方向

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S
Semiramis Ayral‐Kaloustian
H 指数:30论文数:121被引数:3,129
K
Ker Yu
H 指数:40论文数:118被引数:5,507
J
Joshua A. Kaplan
H 指数:23论文数:67被引数:1,887
B
Brent R. Stockwell
H 指数:103论文数:328被引数:12.1万
T
Tarek S. Mansour
H 指数:50论文数:245被引数:6,675
J
Judy Lucas
H 指数:38论文数:190被引数:5,568
L
Lourdes Toral‐Barza
H 指数:28论文数:74被引数:3,044
J
Jeroen C. Verheijen
H 指数:22论文数:51被引数:1,675
J
James J. Gibbons
H 指数:27论文数:154被引数:4,637
K
Kevin J. Curran
H 指数:46论文数:190被引数:1.7万