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L

Lisa Alexander

metagenomi therapeutics
H指数:14
被引数:1,005

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Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency

Cas12f直系同源物的比较表征揭示了增强基因组编辑效率的机制特征

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2026-04-130
OAAI
Kaoling Guan; Rodrigo Fregoso Ocampo; Paula B. Matheus Carnevali; Cindy J. Castelle; Liliana Gonzalez-Osorio; Dominic T. Castanzo; Nicole C. Thomas; Molly Brothers; Tyler L. Dangerfield; Matthew M. Hooper; Madeline S. West; Nathan M. Appleby; Isabella Krudop; Rebecca C. Lamothe; Daniela S. Aliaga Goltsman; Lisa M. Alexander; Cristina N. Butterfield; Kenneth A. Johnson; Christopher T. Brown; David W. Taylor
Integration of therapeutic cargo into the human genome with programmable type V-K CAST

利用可编程V-K型CAST将治疗性载荷整合到人类基因组中

NATURE COMMUNICATIONS
IF15.7
2025-03-131
OA
Liu, Jason; Goltsman, Daniela S. Aliaga; Alexander, Lisa M.; Khayi, Khak Khak; Hong, Jennifer H.; Dunham, Drew T.; Romano, Christine A.; Temoche-Diaz, Morayma M.; Chadha, Shailaja; Ocampo, Rodrigo Fregoso; Oki-O'Connell, Jennifer; Janson, Owen P.; Turcios, Keirstinne; Gonzalez-Osorio, Liliana; Muysson, Jared; Rahman, Jenat; Laperriere, Sarah M.; Devoto, Audra E.; Castelle, Cindy J.; Butterfield, Cristina N.; Cost, Gregory J.; Brown, Christopher T.; Thomas, Brian C.
DNA targeting by compact Cas9d and its resurrected ancestor

紧凑型Cas9d的DNA靶向作用及其复活祖先

NATURE COMMUNICATIONS
IF15.7
2025-01-071
OA
Ocampo, Rodrigo Fregoso; Bravo, Jack P. K.; Dangerfield, Tyler L.; Nocedal, Isabel; Jirde, Samatar A.; Alexander, Lisa M.; Thomas, Nicole C.; Das, Anjali; Nielson, Sarah; Johnson, Kenneth A.; Brown, Christopher T.; Butterfield, Cristina N.; Goltsman, Daniela S. A.; Taylor, David W.
Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability
CRISPR JOURNAL
IF4
2023-06-012
OAAI
Alexander, Lisa M. M.; Goltsman, Daniela S. Aliaga S.; Liu, Jason; Lin, Jyun-Liang; Temoche-Diaz, Morayma M. M.; Laperriere, Sarah M. M.; Neerincx, Andreas; Bednarski, Christien; Knyphausen, Philipp; Cohnen, Andre; Albers, Justine; Gonzalez-Osorio, Liliana; Ocampo, Rodrigo Fregoso; Oki, Jennifer; Devoto, Audra E. E.; Castelle, Cindy J. J.; Lamothe, Rebecca C. C.; Cost, Gregory J. J.; Butterfield, Cristina N. N.; Thomas, Brian C. C.; Brown, Christopher T. T.

研究方向

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C
Carlos Bustamante
H 指数:113论文数:568被引数:5.2万
C
Christopher T. Brown
H 指数:41论文数:149被引数:1.4万
R
Rodrigo Fregoso Ocampo
H 指数:5论文数:11被引数:94
C
Cristina N. Butterfield
H 指数:13论文数:34被引数:3,791
D
Daniela S. Aliaga Goltsman
H 指数:14论文数:46被引数:3,273
B
Brian C. Thomas
H 指数:70论文数:171被引数:2.3万
A
Audra E. Devoto
H 指数:8论文数:11被引数:910
G
Gregory J. Cost
H 指数:33论文数:68被引数:1.2万
C
Cindy J. Castelle
H 指数:34论文数:89被引数:1.1万
J
Jason Liu
H 指数:28论文数:100被引数:9,490