Dylan Scott Eiger - Publications, H-index & Citations

Dylan Scott Eiger

University of Pennsylvania

9H指数

30论文数

419被引数

收录论文 18

发表时间

Identifying conserved G protein-coupled receptor protein interactions independent of heterotrimeric G proteins and β-arrestins 鉴定与异源三聚体G蛋白和β-抑制蛋白无关的G蛋白偶联受体蛋白相互作用

PNAS Nexus

IF3.8

2026-09-25

OAAI

Chloe Hicks; Julia Gardner; Anand Chundi; Nicholas D Camarda; Chanpreet Jassal; Uyen Pham; Saisha Dhar; Hailey Rodriguez; J Fernando Bazan; Dylan Scott Eiger; Sudarshan Rajagopal; null

The promise of biased ligands in therapeutics 偏向配体在治疗领域的应用前景

Pharmacological Reviews

IF17.3

2026-09-04

PREAI

Dylan S. Eiger; Jeffrey S. Smith; Sudarshan Rajagopal

Location-biased β-arrestin conformations direct GPCR signaling 位置偏好性的β-arrestin构象指导GPCR信号传导

Science Signaling

IF6.6

2026-03-24

PREAI

Uyen Pham; Anand Chundi; Tomasz M. Stępniewski; Srikrishna Darbha; Dylan S. Eiger; Sonia Gazula; Julia Gardner; Chloe Hicks; Jana Selent; Sudarshan Rajagopal

Avoiding Rash Decisions

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2024-10-03

PREAI

Eiger, Dylan S.; Curtis, Monica R.; Eisenberg, Staci; Walker, Katherine H.; Loscalzo, Joseph

GPCR kinases differentially modulate biased signaling downstream of CXCR3 depending on their subcellular localization

SCIENCE SIGNALING

IF6.6

2024-02-13

OAAI

Gardner, Julia; Eiger, Dylan Scott; Hicks, Chloe; Choi, Issac; Pham, Uyen; Chundi, Anand; Namjoshi, Ojas; Rajagopal, Sudarshan

Location bias: A Hidden Variable in GPCR pharmacology

BIOESSAYS

IF2.7

2023-08-25

PREAI

Eiger, Dylan Scott; Hicks, Chloe; Gardner, Julia; Pham, Uyen; Rajagopal, Sudarshan

Phosphorylation barcodes direct biased chemokine signaling at CXCR3

CELL CHEMICAL BIOLOGY

IF7.2

2023-04-01

OAAI

Eiger, Dylan S.; Smith, Jeffrey S.; Shi, Tujin; Stepniewski, Tomasz Maciej; Tsai, Chia-Feng; Honeycutt, Christopher; Boldizsar, Noelia; Gardner, Julia; Nicora, Carrie D.; Moghieb, Ahmed M.; Kawakami, Kouki; Choi, Issac; Hicks, Chloe; Zheng, Kevin; Warman, Anmol; Alagesan, Priya; Knape, Nicole M.; Huang, Ouwen; Silverman, Justin D.; Smith, Richard D.; Inoue, Asuka; Selent, Jana; Jacobs, Jon M.; Rajagopal, Sudarshan

Location bias contributes to functionally selective responses of biased CXCR3 agonists

NATURE COMMUNICATIONS

IF15.7

2022-10-04

OAAI

Eiger, Dylan Scott; Boldizsar, Noelia; Honeycutt, Christopher Cole; Gardner, Julia; Kirchner, Stephen; Hicks, Chloe; Choi, Issac; Pham, Uyen; Zheng, Kevin; Warman, Anmol; Smith, Jeffrey; Zhang, Jennifer; Rajagopal, Sudarshan

Phosphorylation barcode ensembles encoded by biased CXCR3 agonists direct non-redundant chemokine signaling

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Eiger, Dylan S.; Smith, Jeffrey; Shi, Tujin; Stepniewski, Tomasz M.; Honeycutt, Christopher; Boldizsar, Noelia; Gardner, Julia; Tsai, Chia-Feng; Nicora, Carrie; Moghieb, Ahmed; Kawakami, Kouki

Location Bias Contributes to Functionally Selective Responses of Biased CXCR3 Agonists to Regulate Inflammation

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Gardner, Julia; Eiger, Dylan; Boldizsar, Noelia; Honcvcutt, Christopher C.; Kirchner, Stephen; Hicks, Chloe; Choi, Issac; Zheng, Kevin; Warman, Anmol; Smith, Jaffrey

GPCR systems pharmacology: a different perspective on the development of biased therapeutics

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2022-05-01

OAAI

Eiger, Dylan Scott; Pham, Uyen; Gardner, Julia; Hicks, Chloe; Rajagopal, Sudarshan

Biased agonists of the chemokine receptor CXCR3 differentially signal through Gαi:β-arrestin complexes

SCIENCE SIGNALING

IF6.6

2022-03-22

OAAI

Zheng, Kevin; Smith, Jeffrey S.; Eiger, Dylan S.; Warman, Anmol; Choi, Issac; Honeycutt, Christopher C.; Boldizsar, Noelia; Gundry, Jaimee N.; Pack, Thomas F.; Inoue, Asuka; Caron, Marc G.; Rajagopal, Sudarshan

Differential GRK Recruitment and the Phosphorylation Barcode as a Mechanism for Biased Agonism at G Protein-Coupled Receptors

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Gardner, Julia; Eiger, Dylan; Honeycutt, Christopher; Boldizsar, Noelia; Choi, Issac; Rajagopal, Sudarshan

Sympathetic and Parasympathetic Regulation of NF-κB by GPCRs through the modulation of interactions between p65/RelA and the β-arrestins

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Honeycutt, Christopher; Eiger, Dylan; Boldizsar, Noelia; Gardner, Julia; Rajagopal, Sudarshan

Receptor Endocytosis as a Mechanism of Biased Agonism at CXCR3

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Boldizsar, Noelia; Eiger, Dylan; Honeycutt, Cole; Gardner, Julia; Rajagopal, Sudarshan

Biased agonism at chemokine receptors

CELLULAR SIGNALLING

IF3.7

2021-02-01

OAAI

Eiger, Dylan Scott; Boldizsar, Noelia; Honeycutt, Christopher Cole; Gardner, Julia; Rajagopal, Sudarshan

Medical Students' Reflections on the Recent Changes to the USMLE Step Exams

ACADEMIC MEDICINE

IF5.2

2020-11-17

OAAI

Cangialosi, Peter T.; Chung, Brian C.; Thielhelm, Torin P.; Camarda, Nicholas D.; Eiger, Dylan S.

Biased Agonism at CXCR3 Drives Differential Phosphoproteomic and Transcriptomic Profiles and Cellular Outputs

FASEB JOURNAL

IF4.2

2020-04-20

PREAI

Eiger, Dylan; Smith, Jeffrey; Tsai, Chia-Feng; Jacobs, Jon; Shi, Tujin; Rajagopal, Sudarshan

研究方向