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收藏分享 收藏 分享 收藏 Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening (vol 64, pg 4580, 2024)
Piga, Martina; Varga, Zoltan; Feher, Adam; Papp, Ferenc; Korpos, Eva; Bangera, Kavya C.; Frlan, Rok; Ilas, Janez; Dernovsek, Jaka; Tomasic, Tihomir; Zidar, Nace 分享 收藏 Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders隐藏在视线中: 将拓扑异构酶iia抑制剂优化为Hsp90β 选择性结合剂Dernovsek, Jaka; Gorican, Tjasa; Gedgaudas, Marius; Zajec, Ziva; Urbancic, Dunja; Jug, Ana; Skok, Ziga; Sturtzel, Caterina; Distel, Martin; Grdadolnik, Simona Golic; Babu, Kesavan; Panchamatia, Ashna; Stachowski, Timothy R.; Fischer, Marcus; Ilas, Janez; Zubriene, Asta; Matulis, Daumantas; Zidar, Nace; Tomasic, Tihomir 分享 收藏 分享 收藏 Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strainsZidar, Nace; Onali, Alessia; Persolja, Peter; Tiz, Davide Benedetto; Dernovsek, Jaka; Skok, Ziga; Durcik, Martina; Cotman, Andrej Emanuel; Rambaher, Martina Hrast; Cruz, Cristina D.; Tammela, Paivi; Senerovic, Lidija; Jovanovic, Milija; Szili, Petra Eva; Czikkely, Marton Simon; Pal, Csaba; Zega, Anamarija; Masic, Lucija Peterlin; Ilas, Janez; Tomasic, Tihomir; Kikelj, Danijel 分享 收藏 Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study探索N-(benzothiazol-2-yl) 吡咯酰胺DNA促旋酶抑制剂与GyrB ATP结合位点亲脂性底板的相互作用: 药物化学和QTAIM研究Zidar, Nace; Cotman, Andrej Emanuel; Sinnige, Wessel; Benek, Ondrej; Barancokova, Michaela; Zega, Anamarija; Masic, Lucija Peterlin; Tomasic, Tihomir; Ilas, Janez; Henderson, Sara R.; Mundy, Julia E. A.; Maxwell, Anthony; Stevenson, Clare E. M.; Lawson, David M.; Sterk, Geert Jan; Tosso, Rodrigo; Gutierrez, Lucas; Enriz, Ricardo D.; Kikelj, Danijel 分享 收藏 分享 收藏 Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual ScreeningPiga, Martina; Varga, Zoltan; Feher, Adam; Papp, Ferenc; Korpos, Eva; Bangera, Kavya C.; Frlan, Rok; Ilas, Janez; Dernovsek, Jaka; Tomasic, Tihomir; Zidar, Nace 分享 收藏 Immunosuppressive effects of new thiophene-based KV1.3 inhibitorsGubic, Spela; Montalbano, Alberto; Sala, Cesare; Becchetti, Andrea; Hendrickx, Louise Antonia; Van Theemsche, Kenny M.; Pinheiro-Junior, Ernesto Lopes; Altadonna, Ginevra Chioccioli; Peigneur, Steve; Ilas, Janez; Labro, Alain J.; Pardo, Luis A.; Tytgat, Jan; Tomasic, Tihomir; Arcangeli, Annarosa; Masic, Lucija Peterlin 分享 收藏 Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE PathogensSterle, Masa; Durcik, Martina; Stevenson, Clare E. M.; Henderson, Sara R.; Szili, Petra Eva; Czikkely, Marton; Lawson, David M.; Maxwell, Anthony; Cahard, Dominique; Kikelj, Danijel; Zidar, Nace; Pal, Csaba; Masic, Lucija Peterlin; Ilas, Janez; Tomasic, Tihomir; Cotman, Andrej Emanuel; Zega, Anamarija 分享 收藏 New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureusDurcik, Martina; Cotman, Andrej Emanuel; Toplak, Zan; Mozina, Stefan; Skok, Ziga; Szili, Petra Eva; Czikkely, Marton; Maharramov, Elvin; Vu, Thu Hien; Piras, Maria Vittoria; Zidar, Nace; Ilas, Janez; Zega, Anamarija; Trontelj, Jurij; Pardo, Luis A.; Hughes, Diarmaid; Huseby, Douglas; Berruga-Fernandez, Talia; Cao, Sha; Simoff, Ivailo; Svensson, Richard; Korol, Sergiy V.; Jin, Zhe; Vicente, Francisca; Ramos, Maria C.; Mundy, Julia E. A.; Maxwell, Anthony; Stevenson, Clare E. M.; Lawson, David M.; Glinghammar, Bjorn; Sjostrom, Eva; Bohlin, Martin; Oreskar, Joanna; Alver, Sofie; Janssen, Guido V.; Sterk, Geert Jan; Kikelj, Danijel; Pal, Csaba; Tomasic, Tihomir; Masic, Lucija Peterlin 分享 收藏 ATP-competitive inhibitors of human DNA topoisomerase II? with improved antiproliferative activity based on N-phenylpyrrolamide scaffoldSkok, Ziga; Durcik, Martina; Zajex, Ziva; Skledar, Darja Gramec; Bozovic, Kristof; Pis, Anja; Tomas, Tihomir; Zega, Anamarija; Mas, Lucija Peterlin; Kikelj, Danijel; Zidar, Nace; Ilas, Janez 分享 收藏 Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosaCotman, Andrej Emanuel; Durcik, Martina; Tiz, Davide Benedetto; Fulgheri, Federica; Secci, Daniela; Sterle, Masa; Mozina, Stefan; Skok, Ziga; Zidar, Nace; Zega, Anamarija; Ilas, Janez; Masic, Lucija Peterlin; Tomasic, Tihomir; Hughes, Diarmaid; Huseby, Douglas L.; Cao, Sha; Garoff, Linnea; Fernandez, Talia Berruga; Giachou, Paraskevi; Crone, Lisa; Simoff, Ivailo; Svensson, Richard; Birnir, Bryndis; Korol, Sergiy V.; Jin, Zhe; Vicente, Francisca; Ramos, Maria C.; de la Cruz, Mercedes; Glinghammar, Bjorn; Lenhammar, Lena; Henderson, Sara R.; Mundy, Julia E. A.; Maxwell, Anthony; Stevenson, Clare E. M.; Lawson, David M.; Janssen, Guido V.; Sterk, Geert Jan; Kikelj, Danijel 分享 收藏 Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors下一代杂环亲电试剂作为小分子共价MurA抑制剂Abranyi-Balogh, Peter; Keeley, Aaron; Ferenczy, Gyorgy G.; Petri, Laszlo; Imre, Timea; Grabrijan, Katarina; Hrast, Martina; Knez, Damijan; Ilas, Janez; Gobec, Stanislav; Keseru, Gyorgy M. 分享 收藏 Design, Synthesis, in vitro and in silico Characterization of 2-Quinolone-L-alaninate-1,2,3-triazoles as Antimicrobial AgentsMoussaoui, Oussama; Bhadane, Rajendra; Sghyar, Riham; Ilas, Janez; El Hadrami, El Mestafa; Chakroune, Said; Salo-Ahen, Outi M. H. 分享 收藏 分享 收藏 Exploring protein hotspots by optimized fragment pharmacophores通过优化片段药效团探索蛋白质热点Bajusz, David; Wade, Warren S.; Satala, Grzegorz; Bojarski, Andrzej J.; Ilas, Janez; Ebner, Jessica; Grebien, Florian; Papp, Henrietta; Jakab, Ferenc; Douangamath, Alice; Fearon, Daren; von Delft, Frank; Schuller, Marion; Ahel, Ivan; Wakefield, Amanda; Vajda, Sandor; Gerencser, Janos; Pallai, Peter; Keseru, Gyoergy M. 分享 收藏 New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens对ESKAPE病原体具有活性的细菌DNA旋转酶和拓扑异构酶IV的新型双重ATP竞争性抑制剂Durcik, Martina; Nyerges, Akos; Skok, Ziga; Skledar, Darja Gramec; Trontelj, Jurij; Zidar, Nace; Ilas, Janez; Zega, Anamarija; Cruz, Cristina D.; Tammela, Paivi; Welin, Martin; Kimbung, Yengo R.; Focht, Dorota; Benek, Ondrej; Revesz, Tamas; Draskovits, Gabor; Szili, Petra Eva; Daruka, Lejla; Pal, Csaba; Kikelj, Danijel; Masic, Lucija Peterlin; Tomasic, Tihomir 分享 收藏 
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