Thomas Fath - Publications, H-index & Citations

Thomas Fath

macquarie university

31H指数

98论文数

3.5K被引数

收录论文 33

发表时间

Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosis 棘层分化蛋白超磷酸化触发了散发性肌萎缩侧索硬化症中的TDP-43病理。

Brain

IF11.7

2026-03-10

OAAI

Cyril Jones Jagaraj; Sayanthooran Saravanabavan; Sonam Parakh; Mrithulabashini Jayakumar; Sara Assar Kashani; Sina Shadfar; Prachi Mehta; Shashi Gautam; Fabiha Farzana; Alexandra K Suchowerska; Kuok Yap; Marta Vidal; Audrey M G Ragagnin; Md Shafi Jamali; Shu Yang; Thomas Fath; David Craik; Julie D Atkin

Knock-out of Tpm4.2/Actin Filaments Alters Neuronal Signaling, Neurite Outgrowth, and Behavioral Phenotypes in Mice Tpm4.2/肌动蛋白丝的敲除改变了小鼠的神经元信号传导、神经突生长和行为表型。

Molecular Neurobiology

IF4.3

2025-08-02

OAAI

Sian Genoud; Chanchanok Chaichim; Rossana Rosa Porto; Tamara Tomanic; Holly Stefen; Esmeralda Paric; Soumalya Sarkar; Dasol Yoo; Wendi Gao; Edna C. Hardeman; Peter W. Gunning; Tim Karl; John Power; Thomas Fath

Engineered Cyclotide Blocks Neuronal Excitotoxicity

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-12-04

PREAI

Ariawan, Daryl; van der Hoven, Julia; Morey, Nicolle; Pushpitha, Kanishka; Genoud, Sian; Stefen, Holly; Veltman, Sanne; Przybyla, Magdalena; Deng, Yuanyuan; Fath, Thomas; Tietz, Ole; van Eerse, Janet; Ittner, Lars Matthias

Tau target identification reveals NSF-dependent effects on AMPA receptor trafficking and memory formation Tau靶标鉴定揭示了NSF对AMPA受体运输和记忆形成的依赖作用

EMBO JOURNAL

IF8.3

2022-08-22

OAAI

Prikas, Emmanuel; Paric, Esmeralda; Asih, Prita R.; Stefanoska, Kristie; Stefen, Holly; Fath, Thomas; Poljak, Anne; Ittner, Arne

The Nature of Diamino Linker and Halogen Bonding Define Selectivity of Pyrrolopyrimidine-Based LIMK1 Inhibitors

FRONTIERS IN CHEMISTRY

IF4.2

2021-12-13

OAAI

Ariawan, Daryl; Au, Carol; Paric, Esmeralda; Fath, Thomas; Ke, Yazi D.; Kassiou, Michael; van Eersel, Janet; Ittner, Lars M.

Syntaxins 6 and 8 facilitate tau into secretory pathways

BIOCHEMICAL JOURNAL

IF4.3

2021-04-16

OAAI

Lee, Wei Siang; Tan, Daniel C. S.; Deng, Yuanyuan; van Hummel, Annika; Ippati, Stefania; Stevens, Claire; Carmona-Mora, Paulina; Ariawan, Daryl; Hou, Liming; Stefen, Holly; Tomanic, Tamara; Bi, Mian; Tomasetig, Florence; Martin, Adam; Fath, Thomas; Palmer, Stephen; Ke, Yazi D.; Ittner, Lars M.

Deletion of the Actin-Associated Tropomyosin Tpm3 Leads to Reduced Cell Complexity in Cultured Hippocampal Neurons-New Insights into the Role of the C-Terminal Region of Tpm3.1

CELLS

IF5.2

2021-03-23

OAAI

Tomanic, Tamara; Martin, Claire; Stefen, Holly; Paric, Esmeralda; Gunning, Peter; Fath, Thomas

Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-18

OAAI

Ippati, Stefania; Deng, Yuanyuan; van der Hoven, Julia; Heu, Celine; van Hummel, Annika; Chua, Sook Wern; Paric, Esmeralda; Chan, Gabriella; Feiten, Astrid; Fath, Thomas; Ke, Yazi D.; Haass, Nikolas K.; Ittner, Lars M.

CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis CYLD是额颞叶痴呆-肌萎缩性侧索硬化症的致病基因

BRAIN

IF11.7

2020-03-23

OAAI

Dobson-Stone, Carol; Hallupp, Marianne; Shahheydari, Hamideh; Ragagnin, Audrey M. G.; Chatterton, Zac; Carew-Jones, Francine; Shepherd, Claire E.; Stefen, Holly; Paric, Esmeralda; Fath, Thomas; Thompson, Elizabeth M.; Blumbergs, Peter; Short, Cathy L.; Field, Colin D.; Panegyres, Peter K.; Hecker, Jane; Nicholson, Garth; Shaw, Alex D.; Fullerton, Janice M.; Luty, Agnes A.; Schofield, Peter R.; Brooks, William S.; Rajan, Neil; Bennett, Mark F.; Bahlo, Melanie; Shankaracharya; Landers, John E.; Piguet, Olivier; Hodges, John R.; Halliday, Glenda M.; Topp, Simon D.; Smith, Bradley N.; Shaw, Christopher E.; McCann, Emily; Fifita, Jennifer A.; Williams, Kelly L.; Atkin, Julie D.; Blair, Ian P.; Kwok, John B.

Decoupling the effects of hydrophilic and hydrophobic moieties at the neuron-nanofibre interface

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Martin, Adam D.; Wojciechowski, Jonathan P.; Du, Eric Y.; Rawal, Aditya; Stefen, Holly; Au, Carol G.; Hou, Liming; Cranfield, Charles G.; Fath, Thomas; Ittner, Lars M.; Thordarson, Pall

Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2019-09-27

OAAI

Brettle, Merryn; Stefen, Holly; Djordjevic, Aleksandra; Fok, Sandra Y. Y.; Chan, Josephine W.; van Hummel, Annika; van der Hoven, Julia; Przybyla, Magdalena; Volkerling, Alexander; Ke, Yazi D.; Delerue, Fabien; Ittner, Lars M.; Fath, Thomas

Tropomodulin's Actin-Binding Abilities Are Required to Modulate Dendrite Development

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2018-10-09

OAAI

Gray, Kevin T.; Stefen, Holly; Ly, Thu N. A.; Keller, Christopher J.; Colpan, Mert; Wayman, Gary A.; Pate, Edward; Fath, Thomas; Kostyukova, Alla S.

A Novel Microfluidic Device-Based Neurite Outgrowth Inhibition Assay Reveals the Neurite Outgrowth-Promoting Activity of Tropomyosin Tpm3.1 in Hippocampal Neurons

CELLULAR AND MOLECULAR NEUROBIOLOGY

IF4.8

2018-09-14

PREAI

Stefen, Holly; Hassanzadeh-Barforoushi, Amin; Brettle, Merryn; Fok, Sandra; Suchowerska, Alexandra K.; Tedla, Nicodemus; Barber, Tracie; Warkiani, Majid Ebrahimi; Fath, Thomas

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

NATURE COMMUNICATIONS

IF15.7

2018-08-21

103

OAAI

Turner, Nigel; Lim, Xin Ying; Toop, Hamish D.; Osborne, Brenna; Brandon, Amanda E.; Taylor, Elysha N.; Fiveash, Corrine E.; Govindaraju, Hemna; Teo, Jonathan D.; McEwen, Holly P.; Couttas, Timothy A.; Butler, Stephen M.; Das, Abhirup; Kowalski, Greg M.; Bruce, Clinton R.; Hoehn, Kyle L.; Fath, Thomas; Schmitz-Peiffer, Carsten; Cooney, Gregory J.; Montgomery, Magdalene K.; Morris, Jonathan C.; Don, Anthony S.

Peptide Nanofiber Substrates for Long-Term Culturing of Primary Neurons

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2018-07-06

PREAI

Martin, Adam D.; Chua, Sook Wern; Au, Carol G.; Stefen, Holly; Przybyla, Magdalena; Lin, Yijun; Bertz, Josefine; Thordarson, Pall; Fath, Thomas; Ke, Yazi D.; Ittner, Lars M.

Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain 人脑中天冬氨酰-tRNA合成酶DARS的表达模式

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2018-03-20

OAAI

Frohlich, Dominik; Suchowerska, Alexandra K.; Voss, Carola; He, Ruojie; Wolvetang, Ernst; von Jonquieres, Georg; Simon, Cas; Fath, Thomas; Housley, Gary D.; Klugmann, Matthias

Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2017-12-22

OAAI

Suchowerska, Alexandra K.; Fok, Sandra; Stefen, Holly; Gunning, Peter W.; Hardeman, Edna C.; Power, John; Fath, Thomas

Tau exacerbates excitotoxic brain damage in an animal model of stroke

NATURE COMMUNICATIONS

IF15.7

2017-09-07

138

OAAI

Bi, Mian; Gladbach, Amadeus; van Eersel, Janet; Ittner, Arne; Przybyla, Magdalena; van Hummel, Annika; Chua, Sook Wern; van der Hoven, Julia; Lee, Wei S.; Mueller, Julius; Parmar, Jasneet; von Jonquieres, Georg; Stefen, Holly; Guccione, Ernesto; Fath, Thomas; Housley, Gary D.; Klugmann, Matthias; Ke, Yazi D.; Ittner, Lars M.

In vivo characterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL

NEUROBIOLOGY OF DISEASE

IF5.6

2017-01-01

OAAI

Frohlich, Dominik; Suchowerska, Alexandra K.; Spencer, Ziggy H. T.; von Jonquieres, Georg; Klugmann, Claudia B.; Bongers, Andre; Delerue, Fabien; Stefen, Holly; Ittner, Lars M.; Fath, Thomas; Housley, Gary D.; Klugmann, Matthias

Tropomyosins in the healthy and diseased nervous system

BRAIN RESEARCH BULLETIN

IF3.7

2016-09-01

PREAI

Brettle, Merryn; Patel, Shrujna; Fath, Thomas

研究方向