Xian Jia - Publications, H-index & Citations

Xian Jia

shenyang pharmaceutical university

29H指数

137论文数

2.1K被引数

收录论文 58

发表时间

The synthesis and biological evaluation of novel deuterated and non-deuterated aminobenzenesulfonamide derivatives as EGFR inhibitor 新型氘代和非氘代氨基苯磺酰胺衍生物的合成及其作为EGFR抑制剂的生物评价

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2026-04-01

PREAI

Hou, Puzhuang; Zhi, Haitao; Cao, Longcai; Qin, Xiaojin; Yao, Han; Ren, Yuanyuan; Jia, Xian; Li, Xingshu

Chirality Flipping: Engineering LfSDR1 via Opposing Residue Substitutions to Expand the Substrate Scope for Chiral Alcohol Synthesis from Halogen-Substituted Acetophenone Derivatives 手性翻转：通过反向残基替换工程化LfSDR1以扩展来自卤代苯乙酮衍生物的手性醇合成底物范围

The Journal of Organic Chemistry

IF3.6

2026-03-13

PREAI

Yunye Wang; Di Wang; Jiuming Zhang; Yinan Li; Qingyu Wang; Bin Qin; Jingping Ouyang; Xian Jia; Song You

Development and characterization of a novel B7-H3 rabbit monoclonal antibody for glioma diagnosis

Frontiers in Pharmacology

IF4.8

2026-01-23

OAAI

Yue Li†; Zhihong Wang†; Qian Wen; Menghsuen Chiu; Xian Jia; Yijin Li; Xiaoyun Shang

Direct hydrogen atom transfer mediated C-H functionalization enabled by an anthraquinone-based photocatalyst

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

IF4.7

2026-01-21

PREAI

Dongxiao, E.; Ouyang, Jingping; Wang, Xikang; He, Jiayu; Gao, Weimei; Cao, Lukang; You, Song; Jia, Xian

Intrathecal CRISPR-edited allogeneic IL-13Rα2 CAR T Cells for recurrent high-grade Glioma: preclinical characterization and phase I trial 鞘内注射CRISPR编辑的异基因IL-13Rα2 CAR T细胞治疗复发性高级别胶质瘤：临床前表征和I期试验

Nature Communications

IF15.7

2026-01-06

OAAI

Xuetao Li; Xiaoyun Shang; Jiangang Liu; Yang Zhang; Xian Jia; Huabing Li; Yihan Wang; Jianen Gao; Xu Ma; Xuewen Zhang; Xiaoci Rong; Wenjuan Gan; Yu Zhang; Jie Chen; Lin Wang; Zhen Bao; Liang He; Xigang Yan; Yang Liu; Jie Shao; Zongyu Xiao; Zhiming Wang; Haiping Zhu; Zhong Wang; Yuzhang Wu; Yulun Huang

Test and analysis of soil Microscopic parameters on maize seed displacement and Post-Impact behavior based on a vertical Dual-Camera high-speed imaging system 基于垂直双摄像头高速成像系统的土壤微观参数对玉米种子位移及冲击后行为的测试与分析

Computers and Electronics in Agriculture

IF8.9

2025-12-30

PREAI

Xian Jia; Pengfei Zhao; Xiaojun Gao; Zuoli Fu; Gang Guo; Shilin Zhang; Jianxin Dong; Yiming Zhao; Youming Yang; Yuxiang Huang

Rational engineering of R-selective transaminase from Pseudonocardia ammonioxydans for efficient synthesis of chiral β-amino aryl ethers 假单孢菌氨氧化菌中R选择性转氨酶的理性工程改造，用于高效合成手性β-氨基芳基醚

Bioresource Technology

IF9

2025-12-15

PREAI

Xiao Gao; Wenhe Zhang; Qingyu Wang; Zhuobing Zhang; Hongli Wei; Xiaowei Wei; Lu Zhao; Weidong Liu; Xian Jia; Song You

Rational engineering of ketoreductase SsSDR1 for stereoselectivity inversion toward 3-N-substituted azacyclic ketones 酮基还原酶SsSDR1的理性工程改造以实现其对3-N-取代氮杂环酮的立体选择性反转

Bioresource Technology

IF9

2025-10-27

PREAI

Xiao Qiu; Changli Che; Lichun Tang; Bin Qin; Wenhe Zhang; Xian Jia; Song You

Spatial and Electronic Features Driving SGLT1/2 Selectivity: A Combined Molecular Dynamics and Quantum Mechanics Study 驱动SGLT1/2选择性的空间和电子特征：一项结合分子动力学和量子力学的研究

Phys. Chem. Chem. Phys.

IF2.9

2025-08-15

PREAI

Bingkun Chen; Baichun Hu; Yuxiang Zong; Yulong Wang; Lingyi Jing; Zihan Yu; Han Xue; Mingyang Hou; Xian Jia

Synthesis and evaluation of new 5-(1H-1,2,4-triazol-3-yl)-1,2,4-oxadiazole derivatives and their application as OXPHOS inhibitors 新型5-(1H-1,2,4-三唑-3-基)-1,2,4-噁二唑衍生物的合成与评价及其作为OXPHOS抑制剂的应

European Journal of Medicinal Chemistry

IF5.9

2025-06-25

PREAI

Longcai Cao; Han Yao; Puzhuang Hou; Yuanyuan Ren; Haitao Zhi; Xian Jia; Xingshu Li

One-pot photo-biocatalytic cascade reactions for enantioselective synthesis of β-hydroxy sulfones 一锅光生物催化级联反应对映选择性合成 β-羟基砜

MOLECULAR CATALYSIS

IF4.9

2025-02-01

PREAI

Dongxiao, E.; You, Jinge; Zong, Yuxiang; Ma, Qi; Liu, Ran; Che, Changli; Chen, Yang; Tang, Lichun; Li, Jianxin; Jia, Xian

Structure-based reshaping of a new ketoreductase from Sphingobacterium siyangense SY1 toward α-haloacetophenones

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-10-01

PREAI

Che, Changli; Zhang, Wenhe; Xu, Xin; Zheng, Zhiran; Wei, Hongli; Qin, Bin; Jia, Xian; Liu, Weidong; You, Song

Application of Directed Evolution and Machine Learning to Enhance the Diastereoselectivity of Ketoreductase for Dihydrotetrabenazine Synthesis

JACS AU

IF8.7

2024-06-26

OAAI

Huang, Chenming; Zhang, Li; Tang, Tong; Wang, Haijiao; Jiang, Yingqian; Ren, Hanwen; Zhang, Yitian; Fang, Jiali; Zhang, Wenhe; Jia, Xian; You, Song; Qin, Bin

A Three-Step Chemoenzymatic Cascade Synthesis of Miconazole Analogues Based on the Asymmetric Synthesis of β-Heteroaryl Amino Alcohols via Ketoreductases

ADVANCED SYNTHESIS & CATALYSIS

IF4

2023-09-21

PREAI

Fang, Jiali; Xu, Yiping; Ren, Hanwen; Huang, Chenming; Zhang, Wenhe; Jia, Xian; You, Song; Qin, Bin

Stereoselective synthesis of allopregnanolone catalyzed by ketoreductase

MOLECULAR CATALYSIS

IF4.9

2023-09-01

PREAI

Hou, Yue; Lv, Jiaxiang; Guo, Yuzhen; Fang, Jiali; Huang, Chenming; Zhang, Wenhe; Jia, Xian; You, Song; Qin, Bin

A Chemical-Biological Relay Catalytic Method for the Synthesis of (E)-2-Cyanoacrylamides Based on the Catalysis of Amorphous Porphyrin-MOFs and Nitrile Hydratase 基于无定形卟啉-MOFs和腈水合酶催化的化学-生物中继催化方法合成 (E)-2-氰基丙烯酰胺

ADVANCED SYNTHESIS & CATALYSIS

IF4

2023-06-14

PREAI

Zuo, Weiguo; Wang, Guanqun; Yang, Shunbin; Dongxiao, E.; Liu, Lin; Li, Hengyu; You, Song; Jia, Xian

Discovery and Engineering of an Ene-reductase for Kinetic Resolution and Cascade Reduction of Hajos-Parrish/WielandMiescher Ketones

ADVANCED SYNTHESIS & CATALYSIS

IF4

2023-06-13

PREAI

Li, Dongyan; Dong, He; Chen, Xianwen; Li, Yangyang; Xu, Yiping; Wang, Jing; Fang, Jiali; Huang, Chenming; Zhang, Wenhe; Jia, Xian; You, Song; Qin, Bin

A novel NADH-dependent leucine dehydrogenase for multi-step cascade synthesis of L-phosphinothricin

ENZYME AND MICROBIAL TECHNOLOGY

IF3.7

2023-05-01

PREAI

Zhao, Lu; Zhang, Wenhe; Wang, Qi; Wang, Huibin; Gao, Xiao; Qin, Bin; Jia, Xian; You, Song

Development of an enzymatic process for the synthesis of (1S)-2-chloro-1-(3, 4-difluorophenyl) ethanol, the key intermediate of ticagrelor

MOLECULAR CATALYSIS

IF4.9

2023-02-01

PREAI

Che, Changli; Zhang, Wenhe; Men, Yuxi; Li, Hengyu; Qin, Bin; Jia, Xian; You, Song