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I

Ikuo Tooyama

medical innovation research center

49H指数
443论文数
9.9K被引数
收录论文 97
发表时间
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Improving practical steerability of a bidirectional steerable catheter for ERCP by non-straight wire routing通过非直线导丝布线提高ERCP用双向可弯曲导管的实际转向性能
errMEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
IF2.6
err2026-09-01
err0
PREAI
errAtsushi Yamada; Wataru Yonemichi; Ikuo Tooyama; Osamu Inatomi
err分享
err收藏
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2026-07-19
err0
PREAI
errDaijiro Yanagisawa; Takashi Ohgita; Hidekazu Kawashima; Hayato Yoshikawa; Hiroyuki Saito; Ikuo Tooyama; Kazuyuki Takata
err分享
err收藏
Identification of the binding site and immunoreactivity of anti-Aβ antibody 11A1: Comparison with the toxic conformation-specific TxCo-1 antibody抗-Aβ抗体11A1的结合位点及免疫反应性鉴定：与毒性构象特异性TxCo-1抗体的比较
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2025-04-01
err0
PREAI
errFukui, Rara; Hafizal, Uswah; Kageyama, Yusuke; Irie, Yumi; Matsushima, Yuka; Hosoi, Katsuma; Nakayama, Takahisa; Kaneda, Daita; Hashizume, Yoshio; Miki, Kunio; Kita, Akiko; Mukaisho, Ken-ichi; Kushima, Ryoji; Tooyama, Ikuo; Irie, Kazuhiro
err分享
err收藏
Dietary Strategies to Mitigate Alzheimer's Disease: Insights into Antioxidant Vitamin Intake and Supplementation with Microbiota-Gut-Brain Axis Cross-Talk减轻阿尔茨海默病的饮食策略: 通过微生物-肠-脑轴交叉对话对抗氧化维生素摄入和补充的见解
errANTIOXIDANTS
IF6.6
err2024-12-10
err0
errOAAI
errNgah, Wan Zurinah Wan; Ahmad, Hajar Fauzan; Ankasha, Sheril June; Makpol, Suzana; Tooyama, Ikuo
err分享
err收藏
Spatial learning and memory impairment at the post-follicular depletion state is associated with reduced hippocampal glucose uptake(vol 197, 112607, 2024)
errEXPERIMENTAL GERONTOLOGY
IF4.3
err2024-12-01
err0
PREAI
errRamli, Nur Zuliani; Yahaya, Mohamad Fairuz; Fahami, Nur Azlina Mohd; Hamezah, Hamizah Shahirah; Abu Bakar, Zulzikry Hafiz; Arrozi, Aslina Pahrudin; Yanagisawa, Daijiro; Tooyama, Ikuo; Singh, Meharvan; Damanhuri, Hanafi Ahmad
err分享
err收藏
Spatial learning and memory impairment at the post-follicular depletion state is associated with reduced hippocampal glucose uptake
errEXPERIMENTAL GERONTOLOGY
IF4.3
err2024-11-01
err1
errOAAI
errRamli, Nur Zuliani; Yahaya, Mohamad Fairuz; Fahami, Nur Azlina Mohd; Hamezah, Hamizah Shahirah; Abu Bakar, Zulzikry Hafiz; Arrozi, Aslina Pahrudin; Yanagisawa, Daijiro; Tooyama, Ikuo; Singh, Meharvan; Damanhuri, Hanafi Ahmad
err分享
err收藏
Neuronal glutathione depletion elevates the Aβ42/Aβ40 ratio and tau aggregation in Alzheimer's disease mice
errFEBS LETTERS
IF3
err2024-05-24
err1
errOAAI
errHashim, Khairun Nisa Binti; Matsuba, Yukio; Takahashi, Mika; Kamano, Naoko; Tooyama, Ikuo; Saido, Takaomi C.; Hashimoto, Shoko
err分享
err收藏
Association of Arterial Stiffness and Atherosclerotic Burden With Brain Structural Changes Among Japanese Men
errJOURNAL OF THE AMERICAN HEART ASSOCIATION
IF5.3
err2023-06-06
err2
errOAAI
errAzahar, Nazar; Yano, Yuichiro; Kadota, Aya; Shiino, Akihiko H.; Syaifullah, Ali; Miyagawa, Naoko; Kondo, Keiko; Moniruzzaman, Mohammad; Torii, Sayuki; Segawa, Hiroyoshi; Hisamatsu, Takashi; Fujiyoshi, Akira; Nozaki, Kazuhiko; Tooyama, Ikuo; Ueshima, Hirotsugu; Miura, Katsuyuki
err分享
err收藏
Optimization of 3D Immunofluorescence Analysis and Visualization Using IMARIS and MeshLab
errCELLS
IF5.2
err2023-01-04
err4
errOAAI
errAbu Bakar, Zulzikry Hafiz; Bellier, Jean-Pierre; Wan Ngah, Wan Zurinah; Yanagisawa, Daijiro; Mukaisho, Ken-ichi; Tooyama, Ikuo
err分享
err收藏
Pharmaceutical Potential of Casein-Derived Tripeptide Met-Lys-Pro: Improvement in Cognitive Impairments and Suppression of Inflammation in APP/PS1 Mice
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2022-09-27
err0
errOAAI
errTada, Asuka Matsuzaki; Hamezah, Hamizah Shahirah; Arrozi, Aslina Pahrudin; Abu Bakar, Zulzikry Hafiz; Yanagisawa, Daijiro; Tooyama, Ikuo
err分享
err收藏
Optimization of the Linker Length in the Dimer Model of E22P-Aβ40 Tethered at Position 38
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-09-12
err5
PREAI
errChikugo, Ayaka; Irie, Yumi; Tsukano, Chihiro; Uchino, Ayumi; Maki, Takahito; Kume, Toshiaki; Kawase, Taiji; Hirose, Kenji; Kageyama, Yusuke; Tooyama, Ikuo; Irie, Kazuhiro
err分享
err收藏
Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-08-05
err4
PREAI
errUchino, Ayumi; Irie, Yumi; Tsukano, Chihiro; Kawase, Taiji; Hirose, Kenji; Kageyama, Yusuke; Tooyama, Ikuo; Yanagita, Ryo C.; Irie, Kazuhiro
err分享
err收藏
Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer's Disease
errMOLECULES
IF4.6
err2022-04-27
err22
errOAAI
errTakata, Kazuyuki; Kimura, Hiroyuki; Yanagisawa, Daijiro; Harada, Koki; Nishimura, Kaneyasu; Kitamura, Yoshihisa; Shimohama, Shun; Tooyama, Ikuo
err分享
err收藏
A Fluorine-19 Magnetic Resonance Probe, Shiga-Y5, Downregulates Thioredoxin-Interacting Protein Expression in the Brain of a Mouse Model of Alzheimer's Disease
errMOLECULES
IF4.6
err2021-09-02
err1
errOAAI
errArrozi, Aslina Pahrudin; Abu Bakar, Zulzikry Hafiz; Taguchi, Hiroyasu; Yanagisawa, Daijiro; Tooyama, Ikuo
err分享
err收藏
Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-08-31
err15
errOAAI
errKageyama, Yusuke; Irie, Yumi; Matsushima, Yuka; Segawa, Tatsuya; Bellier, Jean-Pierre; Hidaka, Kumi; Sugiyama, Hiroshi; Kaneda, Daita; Hashizume, Yoshio; Akatsu, Hiroyasu; Miki, Kunio; Kita, Akiko; Walker, Douglas G.; Irie, Kazuhiro; Tooyama, Ikuo
err分享
err收藏
Loss of Lysosomal Proteins Progranulin and Prosaposin Associated with Increased Neurofibrillary Tangle Development in Alzheimer Disease溶酶体蛋白前体蛋白和前aposin的丢失与阿尔茨海默氏病的神经原纤维缠结发展增加有关
errJOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
IF3
err2021-08-10
err8
errOAAI
errMendsaikhan, Anarmaa; Tooyama, Ikuo; Serrano, Geidy E.; Beach, Thomas G.; Walker, Douglas G.
err分享
err收藏
Differential accumulation of tau pathology between reciprocal F1 hybrids of rTg4510 mice
errSCIENTIFIC REPORTS
IF3.9
err2021-05-05
err6
errOAAI
errYanagisawa, Daijiro; Hamezah, Hamizah Shahirah; Arrozi, Aslina Pahrudin; Tooyama, Ikuo
err分享
err收藏
Fluorine-19 Magnetic Resonance Imaging for Detection of Amyloid β Oligomers Using a Keto Form of Curcumin Derivative in a Mouse Model of Alzheimer's Disease
errMOLECULES
IF4.6
err2021-03-04
err11
errOAAI
errYanagisawa, Daijiro; Ibrahim, Nor Faeizah; Taguchi, Hiroyasu; Morikawa, Shigehiro; Tomiyama, Takami; Tooyama, Ikuo
err分享
err收藏
Keto form of curcumin derivatives strongly binds to Aβ oligomers but not fibrils
errBIOMATERIALS
IF12.9
err2021-03-01
err27
errOAAI
errYanagisawa, Daijiro; Kato, Tomoko; Taguchi, Hiroyasu; Shirai, Nobuaki; Hirao, Koichi; Sogabe, Takayuki; Tomiyama, Takami; Gamo, Keizo; Hirahara, Yukie; Kitada, Masaaki; Tooyama, Ikuo
err分享
err收藏
Neuroepithelial cell competition triggers loss of cellular juvenescence
errSCIENTIFIC REPORTS
IF3.9
err2020-10-22
err9
errOAAI
errJam, Faidruz Azura; Morimune, Takao; Tsukamura, Atsushi; Tano, Ayami; Tanaka, Yuya; Mori, Yasuhiro; Yamamoto, Takefumi; Nishimura, Masaki; Tooyama, Ikuo; Mori, Masaki
err分享
err收藏

研究方向

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合作学者
合作期刊
J
John C. Gore
H 指数: 131 · 论文数: 1.2K
T
Thomas G. Beach
H 指数: 128 · 论文数: 740
P
Patrick L. McGeer
H 指数: 119 · 论文数: 632
T
Takaomi C. Saido
H 指数: 112 · 论文数: 817
M
Masaki Mori
H 指数: 111 · 论文数: 2.2K
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