Roger S. Armen - Publications, H-index & Citations

Roger S. Armen

university of michigan system

22H指数

138论文数

2.5K被引数

收录论文 25

发表时间

Research Progress on Spike-Dependent SARS-CoV-2 Fusion Inhibitors and Small Molecules Targeting the S2 Subunit of Spike

VIRUSES-BASEL

IF3.5

2024-04-30

OAAI

Freidel, Matthew R.; Armen, Roger S.

The Dual-Targeted Fusion Inhibitor Clofazimine Binds to the S2 Segment of the SARS-CoV-2 Spike Protein

VIRUSES-BASEL

IF3.5

2024-04-20

OAAI

Freidel, Matthew R.; Vakhariya, Pratiti A.; Sardarni, Shalinder K.; Armen, Roger S.

Identification of a β-arrestin- biased negative allosteric modulator for the β2-adrenergic receptor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-25

OAAI

Ippolito, Michael; De Pascali, Francesco; Hopfinger, Nathan; Komolov, Konstantin E.; Laurinavichyute, Daniela; Reddy, Poli Adi Narayana; Sakkal, Leon A.; Rajkowski, Kyle Z.; Nayak, Ajay P.; Lee, Justin; Lee, Jordan; Cao, Gaoyuan; Donover, Preston S.; Reichman, Melvin; An, Steven S.; Salvino, Joseph M.; Penn, Raymond B.; Armen, Roger S.; Scott, Charles P.; Benovic, Jeffrey L.

Identification and pharmacological characterization of a novel β-arrestin-biased negative allosteric modulator of the β

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2023-06-01

OAAI

De Pascali, Francesco F.; Ippolito, Michael; Hopfinger, Nathan; Komolov, Konstantin E.; Laurinavichyute, Daniela K.; Sakkal, Leon A.; Nayak, Ajay P.; Reddy, Poli A. N.; Donover, Preston S.; Reichman, Melvin; Salvino, Joseph M.; Penn, Raymond B.; Armen, Roger S.; Scott, Charles P.; Benovic, Jeffrey L.

β2-Adrenoceptor agonist profiling reveals biased signalling phenotypes for the β2-adrenoceptor with possible implications for the treatment of asthma

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2022-07-19

OAAI

De Pascali, Francesco; Ippolito, Michael; Wolfe, Emily; Komolov, Konstantin E.; Hopfinger, Nathan; Lemenze, Douglas; Kim, Nicholas; Armen, Roger S.; An, Steven S.; Scott, Charles P.; Benovic, Jeffrey L.

Beta-agonist Profiling Reveals Novel Biased Signaling Phenotypes for the Beta 2-adrenergic Receptor with Implications in the Treatment of Asthma

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

De Pascali, Francesco; Ippolito, Michael; Wolfe, Emily; Komolov, Konstantine E.; Hopfinger, Nathan; Lemenze, Douglas; Armen, Roger S.; An, Steven S.; Scott, Charles P.; Benovic, Jeffrey L.

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology

CELL AND BIOSCIENCE

IF6.2

2022-05-07

OAAI

Tsimberidou, Apostolia-Maria; Skliris, Antonis; Valentine, Alan; Shaw, Jamie; Hering, Ursula; Vo, Henry Hiep; Chan, Tung On; Armen, Roger S.; Cottrell, Jeffrey R.; Pan, Jen Q.; Tsichlis, Philip N.

Modeling the Structure-Activity Relationship of Arbidol Derivatives and Other SARS-CoV-2 Fusion Inhibitors Targeting the S2 Segment of the Spike Protein

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2021-12-13

OAAI

Freidel, Matthew R.; Armen, Roger S.

A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-03-01

OAAI

Chan, Tung O.; Armen, Roger S.; Yadav, Santosh; Shah, Sushrut; Zhang, Jin; Tiegs, Brian C.; Keny, Nikhil; Blumhof, Brian; Deshpande, Deepak A.; Rodeck, Ulrich; Penn, Raymond B.

Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methy1-4-phenylisoxazole (P6)

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-09-01

OAAI

Cingolani, Gino; Panella, Andrea; Perrone, Maria Grazia; Vitale, Paola; Di Mauro, Giuseppe; Fortuna, Cosimo G.; Armen, Roger S.; Ferorelli, Savina; Smith, William L.; Scilimati, Antonio

Prediction of consensus binding mode geometries for related chemical series of positive allosteric modulators of adenosine and muscarinic acetylcholine receptors

JOURNAL OF COMPUTATIONAL CHEMISTRY

IF4.8

2017-01-28

OAAI

Sakkal, Leon A.; Rajkowski, Kyle Z.; Armen, Roger S.

Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response

BIOCHEMICAL JOURNAL

IF4.3

2015-09-21

OAAI

Chan, Tung O.; Zhang, Jin; Tiegs, Brian C.; Blumhof, Brian; Yan, Linda; Keny, Nikhil; Penny, Morgan; Li, Xue; Pascal, John M.; Armen, Roger S.; Rodeck, Ulrich; Penn, Raymond B.

Autoregulation of kinase dephosphorylation by ATP binding to AGC protein kinases

CELL CYCLE

IF3.4

2014-10-28

OAAI

Chan, Tung O.; Pascal, John M.; Armen, Roger S.; Rodeck, Ulrich

Systematic and efficient side chain optimization for molecular docking using a cheapest-path procedure 使用最便宜的路径程序进行分子对接的系统有效的侧链优化

JOURNAL OF COMPUTATIONAL CHEMISTRY

IF4.8

2013-02-19

PREAI

Schumann, Marcel; Armen, Roger S.

Targeting the Channel-Calmodulin Interface of Small-Conductance Ca2+-Activated Potassium Channels

BIOPHYSICAL JOURNAL

IF3.1

2013-01-01

OAAI

Zhang, Miao; Pascal, John M.; Schumann, Marcel; Armen, Roger S.; Zhang, Ji-Fang

Identification of the functional binding pocket for compounds targeting small-conductance Ca2+-activated potassium channels

NATURE COMMUNICATIONS

IF15.7

2012-08-28

OAAI

Zhang, Miao; Pascal, John M.; Schumann, Marcel; Armen, Roger S.; Zhang, Ji-Fang

A scalable and accurate method for classifying protein-ligand binding geometries using a MapReduce approach

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2012-07-01

PREAI

Estrada, T.; Zhang, B.; Cicotti, P.; Armen, R. S.; Taufer, M.

Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity Akt激酶通过ATP依赖性构象可塑性对去磷酸化的抗性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-10-26

OAAI

Chan, Tung O.; Zhang, Jin; Rodeck, Ulrich; Pascal, John M.; Armen, Roger S.; Spring, Maureen; Dumitru, Calin D.; Myers, Valerie; Li, Xue; Cheung, Joseph Y.; Feldman, Arthur M.

Evaluation of Several Two-Step Scoring Functions Based on Linear Interaction Energy, Effective Ligand Size, and Empirical Pair Potentials for Prediction of Protein-Ligand Binding Geometry and Free Energy

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2011-06-06

OAAI

Rahaman, Obaidur; Estrada, Trilce P.; Doren, Douglas J.; Taufer, Michela; Brooks, Charles L., III; Armen, Roger S.

The flexible C-terminal arm of the Lassa arenavirus Z-protein mediates interactions with multiple binding partners

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2010-05-06

OAAI

May, Eric R.; Armen, Roger S.; Mannan, Aristotle M.; Brooks, Charles L., III

研究方向