José Luís Rosa - Publications, H-index & Citations

José Luís Rosa

university of barcelona

48H指数

157论文数

1.3W被引数

收录论文 69

发表时间

Proteasome dysfunction underlies HERC2-linked neurodevelopmental disorder with Angelman-like clinical features 蛋白酶体功能障碍是HERC2基因相关的具有Angelman样临床特征的神经发育障碍的基础。

Cell Death Discovery

IF7

2026-04-08

OAAI

Joan Sala‑Gaston; Laura Costa‑Sastre; Manel Garcia‑Diez; Tania López‑Hernández; Juanma Ramírez; Nerea Osinalde; Jose Antonio Valer; Claudia Arnedo‑Pac; Bernat Crosas; Emma L. Baple; Andrew H. Crosby; Ugo Mayor; Francesc Ventura; Jose Luis Rosa

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder

CELL DEATH DISCOVERY

IF7

2024-04-03

OAAI

Sala-Gaston, Joan; Perez-Villegas, Eva M.; Armengol, Jose A.; Rawlins, Lettie E.; Baple, Emma L.; Crosby, Andrew H.; Ventura, Francesc; Rosa, Jose Luis

Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss

MOLECULAR THERAPY

IF12

2023-08-01

OAAI

Pimenta-Lopes, Carolina; Sanchez-de-Diego, Cristina; Deber, Alexandre; Egea-Cortes, Andrea; Valer, Jose Antonio; Alcala, Albert; Mendez-Lucas, Andres; Esteve-Codina, Anna; Rosa, Jose Luis; Ventura, Francesc

HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling

CELL DEATH & DISEASE

IF9.6

2023-01-12

OAAI

Pedrazza, Leonardo; Martinez-Martinez, Arturo; Sanchez-de-Diego, Cristina; Valer, Jose Antonio; Pimenta-Lopes, Carolina; Sala-Gaston, Joan; Szpak, Michal; Tyler-Smith, Chris; Ventura, Francesc; Rosa, Jose Luis

The HERC proteins and the nervous system

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2022-12-01

OAAI

Perez-Villegas, Eva M.; Ruiz, Rocio; Bachiller, Sara; Ventura, Francesc; Armengol, Jose A.; Rosa, Jose Luis

HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2022-10-14

OAAI

Sala-Gaston, Joan; Pedrazza, Leonardo; Ramirez, Juanma; Martinez-Martinez, Arturo; Rawlins, Lettie E.; Baple, Emma L.; Crosby, Andrew H.; Mayor, Ugo; Ventura, Francesc; Rosa, Jose Luis

A new homozygous HERC1 gain-of-function variant in MDFPMR syndrome leads to mTORC1 hyperactivation and reduced autophagy during cell catabolism

MOLECULAR GENETICS AND METABOLISM

IF3.5

2020-09-01

OAAI

Schwarz, Jana Marie; Pedrazza, Leonardo; Stenzel, Werner; Luis Rosa, Jose; Schuelke, Markus; Straussberg, Rachel

The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses

SCIENTIFIC REPORTS

IF3.9

2020-07-21

OAAI

Angeles Montes-Fernandez, Ma; Perez-Villegas, Eva Ma; Garcia-Gonzalo, Francesc R.; Pedrazza, Leonardo; Luis Rosa, Jose; Alvarez de Toledo, Guillermo; Armengol, Jose A.

Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions

ELIFE

IF0

2020-04-07

OAAI

Plana-Bonamaiso, Anna; Lopez-Begines, Santiago; Fernandez-Justel, David; Junza, Alexandra; Soler-Tapia, Ariadna; Andilla, Jordi; Loza-Alvarez, Pablo; Luis Rosa, Jose; Miralles, Esther; Casals, Isidre; Yanes, Oscar; de la Villa, Pedro; Buey, Ruben M.; Mendez, Ana

The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

SCIENTIFIC REPORTS

IF3.9

2020-01-21

OAAI

Pedrazza, Leonardo; Schneider, Taiane; Bartrons, Ramon; Ventura, Francesc; Luis Rosa, Jose

Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2

MOLECULAR ONCOLOGY

IF4.5

2019-11-15

OAAI

Garcia-Cano, Jesus; Sanchez-Tena, Susana; Sala-Gaston, Joan; Figueras, Agnes; Vinals, Francesc; Bartrons, Ramon; Ventura, Francesc; Rosa, Jose Luis

ACVR1 Function in Health and Disease

CELLS

IF5.2

2019-10-31

OAAI

Antonio Valer, Jose; Sanchez-de-Diego, Cristina; Pimenta-Lopes, Carolina; Luis Rosa, Jose; Ventura, Francesc

HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

FRONTIERS IN PHYSIOLOGY

IF3.4

2019-08-07

OAAI

Garcia-Cano, Jesus; Martinez-Martinez, Arturo; Sala-Gaston, Joan; Pedrazza, Leonardo; Luis Rosa, Jose

Inhibition of phosphatidylinositol 3-kinase α (PI3Kα) prevents heterotopic ossification

EMBO MOLECULAR MEDICINE

IF8.3

2019-08-02

OAAI

Antonio Valer, Jose; Sanchez-de-Diego, Cristina; Gamez, Beatriz; Mishina, Yuji; Luis Rosa, Jose; Ventura, Francesc

Large HERCs Function as Tumor Suppressors

FRONTIERS IN ONCOLOGY

IF3.3

2019-06-18

OAAI

Schneider, Taiane; Martinez-Martinez, Arturo; Cubillos-Rojas, Monica; Bartrons, Ramon; Ventura, Francesc; Luis Rosa, Jose

Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway

STEM CELL RESEARCH & THERAPY

IF7.3

2017-12-22

OAAI

Pedrazza, Leonardo; Cubillos-Rojas, Monica; de Mesquita, Fernanda Cristina; Luft, Carolina; Cunha, Aline Andrea; Rosa, Jose Luis; de Oliveira, Jarbas Rodrigues

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

FEBS JOURNAL

IF4.2

2017-09-10

139

OAAI

Rodriguez-Garcia, Ana; Samso, Paula; Fontova, Pere; Simon-Molas, Helga; Manzano, Anna; Castano, Esther; Luis Rosa, Jose; Martinez-Outshoorn, Ubaldo; Ventura, Francesc; Navarro-Sabate, Aurea; Bartrons, Ramon

p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation

CELL DEATH AND DIFFERENTIATION

IF15.4

2017-08-04

OAAI

Artigas, Natalia; Gamez, Beatriz; Cubillos-Rojas, Monica; Sanchez-de Diego, Cristina; Antonio Valer, Jose; Pons, Gabriel; Luis Rosa, Jose; Ventura, Francesc

Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies

SCIENTIFIC REPORTS

IF3.9

2017-06-12

OAAI

Cristina de Mesquita, Fernanda; Guixe-Muntet, Sergi; Fernandez-Iglesias, Anabel; Maeso-Diaz, Raquel; Vila, Sergi; Hide, Diana; Ortega-Ribera, Marti; Luis Rosa, Jose; Carlos Garcia-Pagan, Juan; Bosch, Jaime; Rodrigues de Oliveira, Jarbas; Gracia-Sancho, Jordi

Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2016-02-20

PREAI

Gamez, Beatriz; Rodriguez-Carballo, Edgardo; Graupera, Mariona; Rosa, Jose Luis; Ventura, Francesc

研究方向