Charles E. Chalfant - Publications, H-index & Citations

Charles E. Chalfant

University of Virginia

52H指数

260论文数

9.7K被引数

收录论文 115

发表时间

The lncRNA, CyKILRb acts as a ceRNA for tumor suppressive microRNA to augment oncogenic phenotype via induction of PIK3R2/PI3K/AKT axis 长链非编码RNA CyKILRb作为竞争性内源RNA，通过诱导PIK3R2/PI3K/AKT轴来增强肿瘤抑制性微小RNA的致癌表型

Molecular Therapy Nucleic Acids

IF6.1

2026-08-01

PREAI

Xie, Xiujie; Macknight, H. Patrick; Dziegielewska, Barbara; Lu, Amy L.; Vu, Ngoc Thanh; Chalfant, Charles E.

Sphingolipid Expression During Corneal Wound Healing in a Sphingosine Kinase 1 Knockout Model 鞘脂在鞘氨醇激酶1敲除模型中角膜伤口愈合期间的表達

Cells

IF5.2

2026-04-21

OAAI

Sandip K. Basu; Steve Mabry; Peter Nsiah; Sarah E. Nicholas; Nataliya Lenchik; Mark Altawil; Chi-Yang Chiu; Daniel J. Stephenson; Charles E. Chalfant; Dimitrios Karamichos; Nawajes Mandal

SARS-CoV-2 envelope protein mitochondrial localization reveals host metabolic disruption SARS-CoV-2包膜蛋白的线粒体定位揭示了宿主代谢紊乱

Journal of Biological Chemistry

IF3.9

2026-04-01

OAAI

Emily A. David; Elijah J. Bass; Hannah M. Woods; Daniel Stephenson; Kellyann Román-Cruz; Charles E. Chalfant; Robert V. Stahelin

Oral Supplementation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Can Prevent TBI-Induced Visual, Motor, and Emotional Deficits in Mice 口服补充n-3多不饱和脂肪酸（n-3-PUFA）可预防创伤性脑损伤（TBI）诱导的小鼠视觉、运动和情绪缺陷。

MOLECULAR NEUROBIOLOGY

IF4.3

2025-05-09

OAAI

Mondal, Koushik; Gary, Ashlyn A.; Dash, Anisha; Del Mar, Nobel A.; Stephenson, Daniel J.; Chalfant, Charles E.; Reiner, Anton; Sears, Barry

RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2025-03-01

OAAI

Xie, Xiujie; Macknight, H. Patrick; Lu, Amy L.; Chalfant, Charles E.

Differential lipid signaling from CD4+ and CD8+ T cells contributes to type 1 diabetes development

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-09-18

OAAI

White, Tayleur D.; Almutairi, Abdulaziz; Gai-Tusing, Ying; Stephenson, Daniel J.; Stephenson, Benjamin D.; Chalfant, Charles E.; Lei, Xiaoyong; Lu, Brian; Hammock, Bruce D.; Dilorenzo, Teresa P.; Ramanadham, Sasanka

Selective Reduction of Ca2+-Independent Phospholipase A2β (iPLA2β)-Derived Lipid Signaling From Macrophages Mitigates Type 1 Diabetes Development

DIABETES

IF7.5

2024-09-16

PREAI

Almutairi, Abdulaziz; White, Tayleur D.; Stephenson, Daniel J.; Stephenson, Benjamin D.; Gai-Tusing, Ying; Goel, Paran; Phillips, Daniel W.; Welner, Robert S.; Lei, Xiaoyong; Hammock, Bruce D.; Chalfant, Charles E.; Ramanadham, Sasanka

Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases

LIPIDS IN HEALTH AND DISEASE

IF4.2

2024-06-27

OAAI

Mondal, Koushik; Del Mar, Nobel A.; Gary, Ashlyn A.; Grambergs, Richard C.; Yousuf, Mohd; Tahia, Faiza; Stephenson, Benjamin; Stephenson, Daniel J.; Chalfant, Charles E.; Reiner, Anton; Mandal, Nawajes

Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells

EXPERIMENTAL EYE RESEARCH

IF2.7

2024-05-01

PREAI

Tahia, Faiza; Basu, Sandip K.; Prislovsky, Amanda; Mondal, Koushik; Ma, Dejian; Kochat, Harry; Brown, Kennard; Stephenson, Daniel J.; Chalfant, Charles E.; Mandal, Nawajes

Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum

MBIO

IF4.7

2024-04-10

OAAI

Read, Curtis B.; Ali, Anika N.; Stephenson, Daniel J.; Macknight, H. Patrick; Maus, Kenneth D.; Cockburn, Chelsea L.; Kim, Minjung; Xie, Xiujie; Carlyon, Jason A.; Chalfant, Charles E.

RNA splicing variants of the novel long non-coding RNA, CyKILR, exhibit distinct possess divergent biological functions in lung cancer

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Xie, Xiujie; Macknight, Patrick H.; Lu, Amy L.; Chalfant, Charles E.

Lipids from ocular meibum and tears may serve as biomarkers for depression and post-traumatic stress disorder

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

IF5.6

2023-12-26

OAAI

Gary, Ashlyn A.; Prislovsky, Amanda; Tovar, Arianna; Locatelli, Elyana; Felix, Elizabeth R.; Stephenson, Daniel; Chalfant, Charles E.; Lai, James; Kim, Colin; Mandal, Nawajes; Galor, Anat

Fluoxetine restrains allergic inflammation by targeting an FcRI-ATP positive feedback loop in mast cells

SCIENCE SIGNALING

IF6.6

2023-09-12

OAAI

Haque, Tamara T.; Taruselli, Marcela T.; Kee, Sydney A.; Dailey, Jordan M.; Pondicherry, Neha; Gajewski-Kurdziel, Paula A.; Zellner, Matthew P.; Stephenson, Daniel J.; MacKnight, H. Patrick; Straus, David B.; Kankaria, Roma; Jackson, Kaitlyn G.; Chumanevich, Alena P.; Fukuoka, Yoshihiro; Schwartz, Lawrence B.; Blakely, Randy D.; Oskeritzian, Carole A.; Chalfant, Charles E.; Martin, Rebecca K.; Ryan, John J.

Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function 神经酰胺合成调节脂肪干细胞外泌体MALAT1的生物合成和包装，增加真皮成纤维细胞迁移和线粒体功能

CELL COMMUNICATION AND SIGNALING

IF8.9

2023-08-24

OAAI

Kong, Xaioyuan; Patel, Niketa A.; Chalfant, Charles E.; Cooper, Denise R.

Skewing cPLA2α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis

SCIENCE SIGNALING

IF6.6

2023-07-11

OAAI

Maus, Kenneth D.; Stephenson, Daniel J.; Macknight, H. Patrick; Vu, Ngoc T.; Hoeferlin, L. Alexis; Kim, Minjung; Diegelmann, Robert F.; Xie, Xiujie; Chalfant, Charles E.

Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy

JOURNAL OF LIPID RESEARCH

IF4.1

2023-06-01

OAAI

Stephenson, Daniel J.; MacKnight, H. Patrick; Hoeferlin, L. Alexis; Washington, Sonya L.; Sawyers, Chelsea; Archer, Kellie J.; Strauss III, Jerome F.; Walsh, Scott W.; Chalfant, Charles E.

Inhibition of Epidermal Growth Factor Receptor Signaling by Antisense Oligonucleotides as a Novel Approach to Epidermal Growth Factor Receptor Inhibition 反义寡核苷酸抑制表皮生长因子受体信号作为抑制表皮生长因子受体的新方法

NUCLEIC ACID THERAPEUTICS

IF4.7

2022-10-01

OAAI

Madanayake, Thushara W.; Welsh, Eric A.; Darville, Lancia N. F.; Koomen, John M.; Chalfant, Charles E.; Haura, Eric B.; Robinson, Timothy J.

Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function

MOLECULAR CANCER RESEARCH

IF4.7

2022-05-13

OAAI

Vu, Ngoc T.; Kim, Minjung; Stephenson, Daniel J.; MacKnight, H. Patrick; Chalfant, Charles E.

Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis

MOLECULAR CANCER RESEARCH

IF4.7

2022-04-12

OAAI

Kim, Minjung; Vu, Ngoc T.; Wang, Xue; Bulut, Gamze B.; Wang, Min-Hsuan; Uram-Tuculescu, Cora; Pillappa, Raghavendra; Kim, Sungjune; Chalfant, Charles E.

Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1 神经酰胺激酶通过其受体OXER1抑制5-oxo-ETE的生物合成和信号传导来调节急性伤口愈合

JOURNAL OF LIPID RESEARCH

IF4.1

2022-04-01

OAAI

Maus, Kenneth D.; Stephenson, Daniel J.; Ali, Anika N.; MacKnight, Henry Patrick; Huang, Huey-Jing; Serrats, Jordi; Kim, Minjung; Diegelmann, Robert F.; Chalfant, Charles E.

研究方向