D. Clive Williams - Publications, H-index & Citations

D. Clive Williams

University System of Ohio

59H指数

505论文数

1.3W被引数

收录论文 94

发表时间

Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)

PHARMACEUTICALS

IF4.8

2024-08-05

OAAI

McKeown, James P.; Byrne, Andrew J.; Bright, Sandra A.; Charleton, Clara E.; Kandwal, Shubhangi; Cmelo, Ivan; Twamley, Brendan; McElligott, Anthony M.; Fayne, Darren; O'Boyle, Niamh M.; Williams, D. Clive; Meegan, Mary J.

Physics-Informed Generative Model for Drug-like Molecule Conformers

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-03-15

OAAI

Williams, David C.; Inala, Neil

Tracking the cellular uptake and phototoxicity of Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's base conjugates

RSC CHEMICAL BIOLOGY

IF3.1

2024-01-01

OAAI

Bright, Sandra A.; Erby, Marialuisa; Poynton, Fergus E.; Monteyne, Daniel; Perez-Morga, David; Gunnlaugsson, Thorfinnur; Williams, D. Clive; Elmes, Robert B. P.

Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt's Lymphoma (BL)

MOLECULES

IF4.6

2023-12-14

OAAI

Byrne, Andrew J.; Bright, Sandra A.; McKeown, James. P.; Bergin, Adam; Twamley, Brendan; McElligott, Anthony M.; Noorani, Sara; Kandwal, Shubhangi; Fayne, Darren; O'Boyle, Niamh M.; Williams, D. Clive; Meegan, Mary J.

Real-Time Multi-Photon Tracking and Bioimaging of Glycosylated Theranostic Prodrugs upon Specific Enzyme Triggered Release

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2021-11-24

OAAI

Calatrava-Perez, Elena; Marchetti, Luke A.; McManus, Gavin J.; Lynch, Dylan M.; Elmes, Robert B. P.; Williams, D. Clive; Gunnlaugsson, Thorfinnur; Scanlan, Eoin M.

Synthesis, Characterization, and Biological Profiling of Ruthenium(II)-Based 4-Nitro- and 4-Amino-1,8-naphthalimide Conjugates

INORGANIC CHEMISTRY

IF4.7

2020-07-16

OAAI

Elmes, Robert B. P.; Ryan, Gary J.; Erby, Maria Luisa; Frimannsson, Daniel O.; Kitchen, Jonathan A.; Lawler, Mark; Williams, D. Clive; Quinn, Susan J.; Gunnlaugsson, Thorfinnur

Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's Lymphoma

PHARMACEUTICALS

IF4.8

2020-01-17

OAAI

Byrne, Andrew J.; Bright, Sandra A.; McKeown, James P.; O'Brien, John E.; Twamley, Brendan; Fayne, Darren; Williams, D. Clive; Meegan, Mary J.

4-Amino-1,8-naphthalimide based fluorescent photoinduced electron transfer (PET) pH sensors as liposomal cellular imaging agents: The effect of substituent patterns on PET directional quenching

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING

IF4.5

2019-12-10

PREAI

Martinez-Calvo, Miguel; Bright, Sandra A.; Veale, Emma B.; Henwood, Adam F.; Williams, D. Clive; Gunnlaugsson, Thorfinnur

Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers

ONCOLOGY REPORTS

IF3.9

2019-03-15

OAAI

Bright, S. A.; Byrne, A. J.; Vandenberghe, E.; Browne, P. V.; McElligott, A. M.; Meegan, M. J.; Williams, D. C.

Potent cell cycle inhibitors suitable for treatment of multidrug-resistant tumors

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Sivaraja, Mohan; Sizikov, Sivan; Sirisoma, Nilantha; Kirtadze, Tamari; Chattopadhyay, Madhuri; Ewald, Makena; Dash, Subhadra; Wong, Anne; Neckermann, Georg; To, Elaine; Chang, Stephanie; Shiau, Timothy P.; Williams, David C.; Short, Kevin M.; Estiarte, Angels; Datta, Anirban; Kita, David B.

Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Troger's base-Ru(II)-curcumin organometallic conjugate 新型荧光4-氨基-1，8-萘酰亚胺Troger碱-Ru(II)-姜黄素有机金属缀合物的合成，结构表征和抗增殖活性

CHEMICAL COMMUNICATIONS

IF4.2

2018-01-01

OAAI

Shanmugaraju, Sankarasekaran; Poulsen, Bjorn la Cour; Arisa, Tobi; Umadevi, Deivasigamani; Dalton, Hannah L.; Hawes, Chris S.; Estalayo-Adrian, Sandra; Savyasachi, Aramballi J.; Watson, Graeme W.; Williams, D. Clive; Gunnlaugsson, Thorfinnur

Luminescent Lanthanide Cyclen-Based Enzymatic Assay Capable of Diagnosing the Onset of Catheter-Associated Urinary Tract Infections Both in Solution and within Polymeric Hydrogels

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-12-21

OAAI

Surender, Esther M.; Bradberry, Samuel J.; Bright, Sandra A.; McCoy, Colin P.; Williams, D. Clive; Gunnlaugsson, Thorfinnur

Synthesis, antiproliferative and pro-apoptotic activity of 2-phenylindoles

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-09-01

PREAI

Kelly, Patrick M.; Bright, Sandra A.; Fayne, Darren; Pollock, Jade K.; Zisterer, Daniela M.; Williams, D. Clive; Meegan, Mary J.

Development of novel cyclic peptides as pro-apoptotic agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-07-01

OAAI

Brindisi, Margherita; Maramai, Samuele; Brogi, Simone; Fanigliulo, Emanuela; Butini, Stefania; Guarino, Egeria; Casagni, Alice; Lamponi, Stefania; Bonechi, Claudia; Nathwani, Seema M.; Finetti, Federica; Ragonese, Francesco; Arcidiacono, Paola; Campiglia, Pietro; Valenti, Salvatore; Novellino, Ettore; Spaccapelo, Roberta; Morbidelli, Lucia; Zisterer, Daniela M.; Williams, Clive D.; Donati, Alessandro; Baldari, Cosima; Campiani, Giuseppe; Ulivieri, Cristina; Gemma, Sandra

Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells

INVESTIGATIONAL NEW DRUGS

IF2.7

2016-06-22

PREAI

Lennon, Jennifer C.; Butini, Stefania; Campiani, Giuseppe; O'Meara, Anne; Williams, D. Clive; Zisterer, Daniela M.

The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15

INVESTIGATIONAL NEW DRUGS

IF2.7

2016-02-17

PREAI

Kinsella, Paula; Greene, Lisa M.; Bright, Sandra A.; Pollock, Jade K.; Butini, Stefania; Campiani, Giuseppe; Bauer, Sebastian; Williams, D. Clive; Zisterer, Daniela M.

Luminescent ruthenium polypyridyl complexes with extended 'dppz' like ligands as DNA targeting binders and cellular agents

DALTON TRANSACTIONS

IF3.3

2016-01-01

PREAI

Poulsen, Bjorn C.; Estalayo-Adrian, Sandra; Blasco, Salvador; Bright, Sandra A.; Kelly, John M.; Williams, D. Clive; Gunnlaugsson, Thorfinnur

Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated 'pro-probes'

CHEMICAL COMMUNICATIONS

IF4.2

2016-01-01

OAAI

Calatrava-Perez, Elena; Bright, Sandra A.; Achermann, Stefan; Moylan, Claire; Senge, Mathias O.; Veale, Emma B.; Williams, D. Clive; Gunnlaugsson, Thorfinnur; Scanlan, Eoin M.

Ru(II)-polypyridyl surface functionalised gold nanoparticles as DNA targeting supramolecular structures and luminescent cellular imaging agents

NANOSCALE

IF5.1

2016-01-01

OAAI

Martinez-Calvo, Miguel; Orange, Kim N.; Elmes, Robert B. P.; Poulsen, Bjorn la Cour; Williams, D. Clive; Gunnlaugsson, Thorfinnur

Pre-clinical evaluation of a novel class of anti-cancer agents, the Pyrrolo-1, 5-benzoxazepines

JOURNAL OF CANCER

IF3.2

2016-01-01

OAAI

Greene, L. M.; Butini, S.; Campiani, G.; Williams, D. C.; Zisterer, D. M.

研究方向