Vadim Gaponenko - Publications, H-index & Citations

Vadim Gaponenko

University of Illinois System

36H指数

114论文数

3.9K被引数

收录论文 52

发表时间

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy 不同的TRAPP复合物在分泌和自噬过程中激活Ypt/Rab GTP酶

Journal of Cell Biology

IF6.4

2026-03-09

PREAI

Gyurkovska, Valeriya; Murtazina, Rakhilya; Zhao, Sarah F.; Huppenbauer, Christopher B.; Gaponenko, Vadim; Segev, Nava

Therapeutic targeting of endothelial calcium signaling accelerates the resolution of lung injury 内皮钙信号的治疗靶向加速肺损伤的解决

Signal Transduction and Targeted Therapy

IF52.7

2025-11-18

OAAI

Wan Ching Chan; Man Long Kwok; Xinyan Qu; Hazem Abdelkarim; Jonathan Le; Deying Yang; Avik Banerjee; Shuangping Zhao; Jacob Class; Marlen Gonzalez; Harry Hailemeskel; Raman Ghotra Singh; Ricardo Gallardo-Macias; Vadim J. Gurvich; Mark Maienschein-Cline; Matthew Lindeblad; Kasim Kabirov; Alexander V. Lyubimov; Patrick Belvitch; Justin Richner; Vadim Gaponenko; Yulia A. Komarova

S-Adenosylhomocysteine Analogs Selectively Suppress Pan-Coronavirus Replication by Inhibition of nsp14 Methyltransferase S-腺苷同型半胱氨酸类似物通过抑制nsp14甲基转移酶选择性抑制泛冠状病毒复制

ACS Medicinal Chemistry Letters

IF4

2025-11-05

PREAI

Monica Rosas-Lemus; Sudhakar Athe; George Minasov; Jason A. Pattie; Joseph S. Brunzelle; Irene Chau; Fengling Li; Masoud Vedadi; Heng Ma; Arvind Ramanathan; Mark E. Becker; Thomas J. Hope; Hazem Abdelkarim; Patrick Grudzien; Vadim Gaponenko; Jeffrey E. Montgomery; Raymond E. Moellering; Viresh H. Rawal; Karla J. F. Satchell

Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine 通过直接共价攻击CaaX盒半胱氨酸来阻断KRAS4b的C末端加工

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-05-09

OAAI

Maciag, Anna E.; Yang, Yue; Sharma, Alok K.; Turner, David M.; Dehart, Caroline J.; Abdelkarim, Hazem; Fan, Lixin; Smith, Brian P.; Kumari, Vandana; Dyba, Marcin; Rigby, Megan; Badillo, Jean A. Castillo; Adams, Lauren; Fornelli, Luca; Fox, Stephen; Brafman, Alla; Turbyville, Thomas; Gillette, William; Messing, Simon; Agamasu, Constance; Wolfe, Andrew L.; Gysin, Stephan; Chan, Albert H.; Simanshu, Dhirendra K.; Esposito, Dominic; Chertov, Oleg; Stephen, Andrew G.; Arkin, Michelle; Renslo, Adam; Kelleher, Neil L.; Gaponenko, Vadim; Lightstone, Felice C.; Nissley, Dwight, V; McCormick, Frank

Novel Pan-RAS inhibitor ADT-007: A unique mechanism of antitumor selectivity in pancreatic and colorectal carcinoma models

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wang, Junwei; Keeton, Adam B.; Ramesh, Sindhu; Johnson, Peyton; Maxuitenko, Yulia Y.; Foote, Jeremy B.; Huang, Chung-Hui; Berry, Kristy L.; Fadlalla, Khalda; Reddy, Bandi D.; Nagaraju, Ganji P.; Nurmemmedov, Elmar; Babic, Ivan; Gaponenko, Vadim; Chen, Xi; El-Rayes, Bassel F.; Buchsbaum, Donald J.; Piazza, Gary A.

End binding-3 inhibitor activates regenerative program in age-related macular degeneration 末端结合-3抑制剂激活年龄相关性黄斑变性的再生程序

CELL REPORTS MEDICINE

IF10.6

2023-10-01

OAAI

Lee, Quinn; Chan, Wan Ching; Qu, Xinyan; Sun, Ying; Abdelkarim, Hazem; Le, Jonathan; Saqib, Uzma; Sun, Mitchell Y.; Kruse, Kevin; Banerjee, Avik; Hitchinson, Ben; Geyer, Melissa; Huang, Fei; Guaiquil, Victor; Mutso, Amelia A.; Sanders, Martin; Rosenblatt, Mark I.; Maienschein-Cline, Mark; Lawrence, Matthew S.; Gaponenko, Vadim; Malik, Asrar B.; Komarova, Yulia A.

Development of tolerance to chemokine receptor antagonists: current paradigms and the need for further investigation

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-07-28

OAAI

Grudzien, Patrick; Neufeld, Henry; Ebe Eyenga, Mbasogo; Gaponenko, Vadim

Dorzolamide suppresses PKCd -TIRAP-p38 MAPK signaling axis to dampen the inflammatory response

FUTURE MEDICINAL CHEMISTRY

IF3.4

2023-04-27

OAAI

Rajpoot, Sajjan; Kumar, Ashutosh; Gaponenko, Vadim; Thurston, Teresa L. M.; Mehta, Dolly; Faisal, Syed M.; Zhang, Kam Y. J.; Jha, Hem C.; Darwhekar, Gajanan N.; Baig, Mirza S.

ADT-007 binds RAS and inhibits RAS signaling

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Keeton, Adam B.; Chen, Xi; Valiyaveettil, Jacob; Huang, Chung-Hui; Mattox, Tyler E.; Fadlalla, Khalda; Foote, Jeremy B.; Buchsbaum, Donald J.; Berry, Kristy L.; Nurmemmedov, Elmar; Babic, Ivan; Gaponenko, Vadim; Gorman, Gregory; Coward, Lori; Maxuitenko, Yulia Y.; Smith, Forrest T.; Piazza, Gary A.

The dynamic nature of the K-Ras/calmodulin complex can be altered by oncogenic mutations

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2021-12-01

OAAI

Abdelkarim, Hazem; Leschinsky, Nicholas; Jang, Hyunbum; Banerjee, Avik; Nussinov, Ruth; Gaponenko, Vadim

Data-driven model of the KRas4B/Calmodulin complex

FASEB JOURNAL

IF4.2

2021-05-14

OAAI

Ojeda, Monica; Marcus, Kendra; Jang, Hyunbum; Banerjee, Avik; Makowski, Lee; Nussinov, Ruth; Gaponenko, Vadim; Mattos, Carla

Inhibition of Nonfunctional Ras

CELL CHEMICAL BIOLOGY

IF7.2

2021-02-01

OAAI

Nussinov, Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim

Regulation of the thrombin/protease-activated receptor 1 axis by chemokine (CXC motif) receptor 4

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-10-01

OAAI

Gao, Xianlong; Cheng, You-Hong; Enten, Garrett A.; DeSantis, Anthony J.; Gaponenko, Vadim; Majetschak, Matthias

SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

CELL REPORTS

IF6.9

2020-03-01

OAAI

Joshi, Jagdish C.; Joshi, Bhagwati; Rochford, Ian; Rayees, Sheikh; Akhter, Md Zahid; Baweja, Sukriti; Chava, Koteshwara Rao; Tauseef, Mohammad; Abdelkarim, Hazem; Natarajan, Viswanathan; Gaponenko, Vadim; Mehta, Dolly

Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1 (vol 73, pg 812, 2019)

ONCOGENE

IF7.3

2019-09-17

OAAI

Das, Subhasis; Nair, Rakesh Sathish; Mishra, Rajakishore; Sondarva, Gautam; Viswakarma, Navin; Abdelkarim, Hazem; Gaponenko, Vadim; Sathyanarayana, Pradeep; Rana, Basabi; Rana, Ajay

Vemurafenib Inhibits Active PTK6 in PTEN-null Prostate Tumor Cells

MOLECULAR CANCER THERAPEUTICS

IF5.5

2019-05-01

OAAI

Wozniak, Darren J.; Hitchinson, Ben; Gilic, Milica B.; Bie, Wenjun; Gaponenko, Vadim; Tyner, Angela L.

Novel peptide nanoparticle-biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2019-02-01

OAAI

Grozdanovic, Milica; Laffey, Kimberly G.; Abdelkarim, Hazem; Hitchinson, Ben; Harijith, Anantha; Moon, Hyung-Geon; Park, Gye Young; Rousslang, Lee K.; Masterson, Joanne C.; Furuta, Glenn T.; Tarasova, Nadya I.; Gaponenko, Vadim; Ackerman, Steven J.

Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1

ONCOGENE

IF7.3

2019-01-21

OAAI

Das, Subhasis; Nair, Rakesh Sathish; Mishra, Rajakishore; Sondarva, Gautam; Viswakarma, Navin; Abdelkarim, Hazem; Gaponenko, Vadim; Rana, Basabi; Rana, Ajay

Biased antagonism of CXCR4 avoids antagonist tolerance

SCIENCE SIGNALING

IF6.6

2018-10-16

OAAI

Hitchinson, Ben; Eby, Jonathan M.; Gao, Xianlong; Guite-Vinet, Francois; Ziarek, Joshua J.; Abdelkarim, Hazem; Lee, Youngshim; Okamoto, Yukari; Shikano, Sojin; Majetschak, Matthias; Heveker, Nikolaus; Volkman, Brian F.; Tarasova, Nadya I.; Gaponenko, Vadim

The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling 细菌Ras/Rap1位点特异性内肽酶RRSP通过非典型机制切割Ras以破坏Ras-ERK信号传导

SCIENCE SIGNALING

IF6.6

2018-10-02

OAAI

Biancucci, Marco; Minasov, George; Banerjee, Avik; Herrera, Alfa; Woida, Patrick J.; Kieffer, Matthew B.; Bindu, Lakshman; Abreu-Blanco, Maria; Anderson, Wayne F.; Gaponenko, Vadim; Stephen, Andrew G.; Holderfield, Matthew; Satchell, Karla J. F.

研究方向