Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists甲酰基肽受体2激动剂的杂芳基脲等排物的发现ACS MEDICINAL CHEMISTRY LETTERSIF42022-05-252OA
Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor AgonistsACS MEDICINAL CHEMISTRY LETTERSIF42021-10-226OA
Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical CandidateJOURNAL OF MEDICINAL CHEMISTRYIF6.82021-03-0913PREAI
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In VivoJOURNAL OF MEDICINAL CHEMISTRYIF6.82020-01-283PREAI
Sulfonylated Benzothiazoles as Inhibitors of Endothelial LipaseACS MEDICINAL CHEMISTRY LETTERSIF42018-11-216OAAI
Selective IKur Inhibitors for the Potential Treatment of Atrial Fibrillation: Optimization of the Phenyl Quinazoline Series Leading to Clinical Candidate 5-[5-Phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]pyridine-3-sulfonamideJOURNAL OF MEDICINAL CHEMISTRYIF6.82017-04-2818PREAI
Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor ComplexJOURNAL OF MEDICINAL CHEMISTRYIF6.82016-08-0215PREAI
Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent IKur InhibitorACS MEDICINAL CHEMISTRY LETTERSIF42016-07-0516OAAI
Total synthesis of (-)-rhazinilam: Asymmetric C-H bond activation via the use of a chiral auxiliaryJOURNAL OF THE AMERICAN CHEMICAL SOCIETYIF15.62002-05-23198PREAI
Selective functionalization of amino acids in water: A synthetic method via catalytic C-H bond activationJOURNAL OF THE AMERICAN CHEMICAL SOCIETYIF15.62001-07-31224PREAI
A novel application of a Pd(0)-catalyzed nucleophilic substitution reaction to the regio- and stereoselective synthesis of lactam analogues of the epothilone natural productsJOURNAL OF THE AMERICAN CHEMICAL SOCIETYIF15.62000-08-26160PREAI
C-H bond activation of hydrocarbon segments in complex organic molecules: Total synthesis of the antimitotic rhazinilamJOURNAL OF THE AMERICAN CHEMICAL SOCIETYIF15.62000-06-16139PREAI
Synthesis, structure proof, and biological activity of epothilone cyclopropanesORGANIC LETTERSIF52000-04-2889PREAI
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