Rieko Ishima

university of pittsburgh school of medicine

H指数:35

被引数:4,579

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Conformational asymmetry of human immunodeficiency virus-1 protease flaps increases along the darunavir drug resistance pathway

人类免疫缺陷病毒-1蛋白酶翼区的构象不对称性沿达鲁那韦耐药途径增加

Protein Science

IF5.2

2026-09-260

OAAI

ProstaNet: A Novel Geometric Vector Perceptrons–Graph Neural Network Algorithm for Protein Stability Prediction in Single- and Multiple-Point Mutations with Experimental Validation

ProstaNet：一种用于单点和多点突变蛋白质稳定性预测的几何向量感知器-图神经网络算法，并经实验验证

Research

IF10.7

2025-04-150

Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling

TGF-β与betaglycan及信号受体的结构揭示了复合物组装和信号传导的机制

NATURE COMMUNICATIONS

IF15.7

2025-02-261

An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck

SH3-binding变构调节剂稳定AML相关Src家族激酶Hck的整体构象

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-01-010

OAAI

Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate

MOLECULAR THERAPY ONCOLYTICS

IF5.3

2023-12-016

OAAI

Assessment of Novel Mesothelin-Specific Human Antibody Domain VH-Fc Fusion Proteins-Based PET Agents

ACS OMEGA

IF4.3

2023-11-085

OAAI

Small Molecule Allosteric Modulators of the AML-associated Src-family Kinase, Hck

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-010

PRE

Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation

ACS INFECTIOUS DISEASES

IF3.8

2022-01-058

A highly-specific fully-human antibody and CAR-T cells targeting CD66e/ CEACAM5 are cytotoxic for CD66e-expressing cancer cells in vitro and in vivo

CANCER LETTERS

IF10.1

2022-01-0115

PRE

Effect of Lysyl-tRNA Synthetase on the Maturation of HIV-1 Reverse Transcriptase

ACS OMEGA

IF4.3

2020-06-303

OAAI

Determinants of Active-Site Inhibitor Interaction with HIV-1 RNase H

ACS INFECTIOUS DISEASES

IF3.8

2019-10-0210

OAAI

An NMR strategy to detect conformational differences in a protein complexed with highly analogous inhibitors in solution

METHODS

IF4.3

2018-09-013

OAAI

Binding thermodynamics of metal ions to HIV-1 ribonuclease H domain

JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY

IF3.1

2018-06-096

OAAI

Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-06-017

OAAI

A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-10-0116

OAAI

The HIV-1 p66 homodimeric RT exhibits different conformations in the binding-competent and -incompetent NNRTI site

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2017-09-269

OAAI

Structural Characteristics of the RNAse H Domain in HIV-1 Reverse Transcriptase

BIOPHYSICAL JOURNAL

IF3.1

2017-02-010

OAAI

Structural integrity of the ribonuclease H domain in HIV-1 reverse transcriptase

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2015-07-017

Drug Resistance Mutations Alter Dynamics of Inhibitor-Bound HIV-1 Protease

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2014-06-2634

OAAI

The p66 immature precursor of HIV-1 reverse transcriptase

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2014-05-1227

OAAI

Rieko Ishima

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