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J

John M. Louis

department of health and human services

H指数:61

被引数:1.1万

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Cleavage at the nsp5/nsp6 site of SARS-CoV-2 main protease intermediate precursor is faster from a monomer than a dimer form

SARS-CoV-2主蛋白酶中间前体在nsp5/nsp6位点的裂解，单体形式比二聚体形式更快。

Journal of Biological Chemistry

IF3.9

2026-03-200

OAAI

Molecular mechanisms of protease precursor autoprocessing of RNA viruses: a comprehensive review

RNA病毒蛋白酶前体的自加工分子机制：综合述评

Virology Journal

IF3.8

2026-03-040

OAAI

Solution Domain Dynamics of Monomeric SARS-CoV-2 Main Protease Revealed by Optimized NMR Residual Dipolar Coupling Measurements

单体SARS-CoV-2主要蛋白酶的溶液域动力学通过优化的NMR残余偶极耦合测量揭示

ACS PHYSICAL CHEMISTRY AU

IF4.3

2025-11-010

PRE

Maximum Likelihood Analysis of Diffusing Molecules with Conformational Dynamics in Single-Molecule FRET

单分子FRET中具有构象动力学的扩散分子的最大似然分析

JOURNAL OF PHYSICAL CHEMISTRY B

IF2.9

2025-02-180

PRE

Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations

IF8.7

2024-11-140

OAAI

Effects of SARS-CoV-2 Main Protease Mutations at Positions L50, E166, and L167 Rendering Resistance to Covalent and Noncovalent Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-10-070

PRE

Characterization of alternate encounter assemblies of SARS-CoV-2 main protease

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-09-011

OAAI

Single-Molecule Characterization of Heterogeneous Oligomer Formation during Co-Aggregation of 40-and 42-Residue Amyloid-β

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-08-231

PRE

Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors

COMMUNICATIONS BIOLOGY

IF5.1

2023-11-1311

OAAI

Contribution of the catalytic dyad of SARS-CoV-2 main protease to binding covalent and noncovalent inhibitors

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-07-0114

OAAI

Structures of brain-derived 42-residue amyloid-β fibril polymorphs with unusual molecular conformations and intermolecular interactions

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-0920

OAAI

Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease catalytic domain

COMMUNICATIONS BIOLOGY

IF5.1

2022-09-1619

OAAI

Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease

NATURE COMMUNICATIONS

IF15.7

2022-04-2779

OAAI

Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor

COMMUNICATIONS BIOLOGY

IF5.1

2022-03-0133

OAAI

Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-10-2735

OA

Transient lipid-bound states of spike protein heptad repeats provide insights into SARS-CoV-2 membrane fusion

SCIENCE ADVANCES

IF12.5

2021-10-0830

OAAI

Constraints on the Structure of Fibrils Formed by a Racemic Mixture of Amyloid-β Peptides from Solid-State NMR, Electron Microscopy, and Theory

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-08-1019

OAAI

MWC allosteric model explains unusual hemoglobin-oxygen binding curves from sickle cell drug binding

BIOPHYSICAL JOURNAL

IF3.1

2021-06-0111

OAAI

A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins

IF8.3

2021-03-0118

OA

Fast three-color single-molecule FRET using statistical inference

NATURE COMMUNICATIONS

IF15.7

2020-07-0330

OAAI