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A

Ann Vos

Janssen Pharmaceutica NV
H指数:21
被引数:1,718

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荣誉奖项

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Targeting de novo purine biosynthesis for tuberculosis treatment

靶向从头嘌呤生物合成以治疗结核病

Nature
IF48.5
2025-06-180
OAAI
Dirk A. Lamprecht; Richard J. Wall; Annelies Leemans; Barry Truebody; Joke Sprangers; Patricia Fiogbe; Cadi Davies; Jennefer Wetzel; Stijn Daems; William Pearson; Vanessa Pillay; Samantha Saylock; M. Daniel Ricketts; Ellie Davis; Adam Huff; Tsehai Grell; Shiming Lin; Michelle Gerber; Ann Vos; John Dallow; Sam J. Willcocks; Christine Roubert; Stéphanie Sans; Amandine Desorme; Nicolas Chappat; Aurélie Ray; Mariana Pereira Moraes; Tracy Washington; Hope D’Erasmo; Pavankumar Sancheti; Melissa Everaerts; Mario Monshouwer; Jorge Esquivias; Gerald Larrouy-Maumus; Ruxandra Draghia Akli; Helen Fletcher; Alexander S. Pym; Bree B. Aldridge; Jansy P. Sarathy; Kathleen W. Clancy; Bart Stoops; Neeraj Dhar; Adrie J. C. Steyn; Paul Jackson; Clara Aguilar-Pérez; Anil Koul
Discovery of an Oral, Beyond-Rule-of-Five Mcl-1 Protein-Protein Interaction Modulator with the Potential of Treating Hematological Malignancies
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-04-2810
PRE
Romanov-Michailidis, Fedor; Hsiao, Chien-Chi; Urner, Lorenz M.; Jerhaoui, Soufyan; Surkyn, Michel; Miller, Bradley; Vos, Ann; Blanco, Maria Dominguez; Bueters, Ruud; Vinken, Petra; Bekkers, Mariette; Walker, David; Pietrak, Beth; Eyckmans, Werner; Dores-Sousa, Jose Luis; Koo, Seong Joo; Lento, William; Bauser, Marcus; Philippar, Ulrike; Rombouts, Frederik J. R.
JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-09-2311
PREAI
Rombouts, Frederik J. R.; Kusakabe, Ken-ichi; Alexander, Richard; Austin, Nigel; Borghys, Herman; De Cleyn, Michel; Dhuyvetter, Deborah; Gijsen, Harrie J. M.; Hrupka, Brian; Jacobs, Tom; Jerhaoui, Soufyan; Lammens, Lieve; Leclercq, Laurent; Tsubone, Koichi; Ueno, Tatsuhiko; Morimoto, Kenji; Einaru, Shunsuke; Sumiyoshi, Hirokazu; Van den Bergh, An; Vos, Ann; Surkyn, Michel; Teisman, Ard; Moechars, Diederik
Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-05-1419
PREAI
Vendeville, Sandrine; Tahri, Abdellah; Hu, Lili; Demin, Samuel; Cooymans, Ludwig; Vos, Ann; Kwanten, Leen; Van den Berg, Joke; Battles, Michael B.; McLellan, Jason S.; Koul, Anil; Raboisson, Pierre; Roymans, Dirk; Jonckers, Tim H. M.
Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-07-0227
OAAI
Oehlrich, Daniel; Peschiulli, Aldo; Tresadern, Gary; Van Gool, Michiel; Antonio Vega, Juan; Isabel De Lucas, Ana; Alonso de Diego, Sergio A.; Prokopcova, Hana; Austin, Nigel; Van Brandt, Sven; Surkyn, Michel; De Cleyn, Michel; Vos, Ann; Rombouts, Frederik J. R.; Macdonald, Gregor; Moechars, Dieder; Gijsen, Harrie J. M.; Trabanco, Andres A.
1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2015-10-1067
OAAI
Rombouts, Frederik J. R.; Tresadern, Gary; Delgado, Oscar; Martinez-Lamenca, Carolina; Van Gool, Michiel; Garcia-Molina, Aranzazu; de Diego, Sergio A. Alonso; Oehlrich, Daniel; Prokopcova, Hana; Alonso, Jose Manuel; Austin, Nigel; Borghys, Herman; Van Brandt, Sven; Surkyn, Michel; De Cleyn, Michel; Vos, Ann; Alexander, Richard; Macdonald, Gregor; Moechars, Dieder; Gijsen, Harrie; Trabanco, Andres A.
Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor

Α7烟碱型乙酰胆碱受体激动剂结合域同系物中变构结合位点的分子蓝图

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2015-04-2785
OAAI
Spurny, Radovan; Debaveye, Sarah; Farinha, Ana; Veys, Ken; Vos, Ann M.; Gossas, Thomas; Atack, John; Bertrand, Sonia; Bertrand, Daniel; Danielson, U. Helena; Tresadern, Gary; Ulens, Chris
1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus
JOURNAL OF VIROLOGY
IF3.8
2010-03-1541
OAAI
Nyanguile, Origene; Devogelaere, Benoit; Vijgen, Leen; Van den Broeck, Walter; Pauwels, Frederik; Cummings, Maxwell D.; De Bondt, Hendrik L.; Vos, Ann M.; Berke, Jan M.; Lenz, Oliver; Vandercruyssen, Genevieve; Vermeiren, Katrien; Mostmans, Wendy; Dehertogh, Pascale; Delouvroy, Frederic; Vendeville, Sandrine; VanDyck, Koen; Dockx, Koen; Cleiren, Erna; Raboisson, Pierre; Simmen, Kenneth A.; Fanning, Gregory C.

研究方向

暂未获取到该数据
F
Frederik Rombouts
H 指数:24论文数:80被引数:1,808
G
Gary Tresadern
H 指数:40论文数:166被引数:4,531
H
HillsleyKirk
H 指数:29论文数:99被引数:3,401
A
Aldo Peschiulli
H 指数:10论文数:38被引数:1,083
M
Michel Surkyn
H 指数:11论文数:28被引数:374
M
Michel De Cleyn
H 指数:7论文数:22被引数:252
S
Sven Van Brandt
H 指数:18论文数:42被引数:1,047
A
Andrés A. Trabanco
H 指数:37论文数:134被引数:4,052
N
Nigel Austin
H 指数:20论文数:60被引数:1,872
B
Bradley S. Miller
H 指数:35论文数:246被引数:4,055