未登录 Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19 Poldip2缺陷减轻COVID-19小鼠模型中的肺病严重程度 Hu, Ruinan; Valdivia, Alejandra; White, Taylor; Ju, Willy; Brockman, Maegan L.; Zhang, Zhan; Qu, Hongyan; Gafford, Georgette; Joseph, Giji; Burton, Samantha; Bassit, Leda; Charles, Tysheena P.; Schinazi, Raymond F.; Levit, Rebecca D.; Derdeyn, Cynthia A.; Griendling, Kathy K.; Lassegue, Bernard; Hernandes, Marina S. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Catching our breath: development of interventions and therapies for respiratory syncytial virus 抓住我们的呼吸：呼吸道合胞病毒干预措施和治疗方法的开发 Mathew, Asha Maria; Neilsen, Grace; Lan, Shuiyun; Shooter, Savannah Leanne; Zheng, Jeffrey Shi Jie; Estes, Jeremy; Cao, Dongdong; Schinazi, Raymond F.; Singh, Uma S.; Liang, Bo; Lee, Sujin; Sarafianos, Stefan G. 分享 收藏
Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents 新型二聚体衣壳组装调节剂作为一类独特的强效抗HBV药物 Amblard, Franck; Chen, Zhe; Kra, Kalouna; Patel, Dharmeshkumar; Bassit, Leda; Gargowitsch, Laetitia; Degrouard, Jeril; Rat, Virgile; Arteni, Ana-Andreea; Matthews, Lauren; Ravichandran, Shreya M.; Jiang, Alfred; Athanasiadis, Antonis; Dangas, Georgios; Abate, Maedot; Tresset, Guillaume; Pronost, Julien; Salman, Mohammad; Verma, Kiran; Kirby, Karen A.; Michailidis, Eleftherios; de Rocquigny, Hugues; Durantel, David; Bressanelli, Stephane; Sarafianos, Stefan G.; Schinazi, Raymond F. 分享 收藏
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir (vol 15, pg e00465, 2024) Dinh, Tung; Tber, Zahira; Rey, Juan S.; Mengshetti, Seema; Annamalai, Arun S.; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R.; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F.; Perilla, Juan R.; Kim, Baek; Kvaratskhelia, Mamuka 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
Combating yellow fever virus with 7-deaza-7-fluoro-2′-C-methyladenosine Lecher, Julia C.; Costa, Vivian Vasconcelos; Rust, Lauren N.; Bassit, Leda C.; Patel, Dharmeshkumar; Rezaei, Sahar; Moua, Justin; Santos, Felipe Rocha da Silva; Goncalves, Matheus Rodrigues; Queroz Jr, Celso Martins; Marim, Fernanda Martins; Zhou, Longhu; Lee, Sujin; Mcbrayer, Tamara; De, Ramyani; Azadi, Niloufar; Salman, Mohammad; Zandi, Keivan; Amblard, Franck; Burwitz, Benjamin; Teixeira, Mauro M.; Schinazi, Raymond F. 分享 收藏
Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques Viox, Elise G.; Richard, Jonathan; Grandea, Andres G., III; Nguyen, Kevin; Harper, Justin; Auger, James; Ding, Shilei; Gasser, Romain; Prevost, Jeremie; Marchitto, Lorie; Medjahed, Halima; Bourassa, Catherine; Gaudette, Fleur; Pagliuzza, Amelie; Trifone, Cesar Ariel; Gavegnano, Christina; Hurwitz, Selwyn J.; Park, Jun; Clark, Natasha M.; Hammad, Iman; Capuano III, Saverio; Martin, Malcolm A.; Schinazi, Raymond F.; Silvestri, Guido; Kulpa, Deanna A.; Kumar, Priti; Chomont, Nicolas; Pazgier, Marzena; Smith III, Amos B.; Sodroski, Joseph; Evans, David T.; Finzi, Andres; Paiardini, Mirko 分享 收藏
分享 收藏
The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075 ALG-000184的发现和临床前概况，有效的乙型肝炎病毒衣壳组装调节剂ALG-001075的前药 Vendeville, Sandrine; Amblard, Franck; Bassit, Leda; Beigelman, Leonid N.; Blatt, Lawrence M.; Chen, Xiaoyuan; Chou, Lang; Kum, Dieudonne Buh; Chanda, Sushmita; Deval, Jerome; Geng, Xiu; Gupta, Kusum; Jekle, Andreas; Hu, Haiyang; Hu, Xiaojuan; Kang, Hyunsoon; Liu, Cheng; Liu, Jyanwei; Mcgowan, David C.; Misner, Dinah L.; Raboisson, Pierre; Sanchez, Abel Acosta; Serebryany, Vladimir; Stoycheva, Antitsa D.; Symons, Julian A.; Tan, Hua; Vanrusselt, Hannah; Williams, Caroline; Welch, Michael; Zhang, Liangliang; Zhang, Qingling; Zhang, Yafeng; Schinazi, Raymond F.; Smith, David B.; Debing, Yannick 分享 收藏
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir Dinh, Tung; Tber, Zahira; Rey, Juan S.; Mengshetti, Seema; Annamalai, Arun S.; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R.; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F.; Perilla, Juan R.; Kim, Baek; Kvaratskhelia, Mamuka 分享 收藏
Cannabinoid-Inspired Inhibitors of the SARS-CoV-2 Coronavirus 2′-O-Methyltransferase (2′-O-MTase) Non-Structural Protein (Nsp10-16) Benjamin, Menny M.; Hanna, George S.; Dickinson, Cody F.; Choo, Yeun-Mun; Wang, Xiaojuan; Downs-Bowen, Jessica A.; De, Ramyani; Mcbrayer, Tamara R.; Schinazi, Raymond F.; Nielson, Sarah E.; Hevel, Joan M.; Pandey, Pankaj; Doerksen, Robert J.; Townsend, Danyelle M.; Zhang, Jie; Ye, Zhiwei; Wyer, Scott; Bialousow, Lucas; Hamann, Mark T. 分享 收藏
Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections Hurwitz, Selwyn J.; De, Ramyani; Lecher, Julia C.; Downs-Bowen, Jessica A.; Goh, Shu Ling; Zandi, Keivan; Mcbrayer, Tamara; Amblard, Franck; Patel, Dharmeshkumar; Kohler, James J.; Bhasin, Manoj; Dobosh, Brian S.; Sukhatme, Vikas; Tirouvanziam, Rabindra M.; Schinazi, Raymond F. 分享 收藏
Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers Fan, Zixing; Pavlova, Anna; Jenkins, Matthew C.; Bassit, Leda; Salman, Mohammad; Lynch, Diane L.; Patel, Dharmeshkumar; Korablyov, Maksym; Finn, M. G.; Schinazi, Raymond F.; Gumbart, James C. 分享 收藏
Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease Amblard, Franck; Lecher, Julia C.; De, Ramyani; Zhou, Shaoman; Liu, Peng; Goh, Shu Ling; Tao, Sijia; Patel, Dharmeshkumar; Downs-Bowen, Jessica; Zandi, Keivan; Zhang, Huanchun; Chaudhry, Gitika; McBrayer, Tamara; Muczynski, Michael; Al-Homoudi, Abdullah; Engel, Joseph; Lan, Shuiyun; Sarafianos, Stefan G.; Kovari, Ladislau C.; Schinazi, Raymond F. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
