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Matthias Dobbelstein

university medical center göttingen

49H指数
194论文数
8.4K被引数
收录论文 97
发表时间
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MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNAMDM2与RNA聚合酶III结合并抑制其活性，以抑制细胞质DNA的固有免疫应答
errCell Death and Differentiation
IF15.4
err2026-08-06
err0
errOAAI
errSabrina Weber; Valentina Manzini; Helene Dietrich; Hannah Schotte; Sergei Moshkovskii; Philipp Hackert; Emre Taylan Duman; Nhu Quang Vu; Evangelos Prokakis; Gabriela Salinas; Christof Lenz; Henning Urlaub; Katherine E. Bohnsack; Markus T. Bohnsack; Matthias Dobbelstein
err分享
err收藏
Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells同时靶向KRAS和CDK4协同性地诱导胰腺癌细胞产生持久的生长抑制
errCell Death & Disease
IF9.6
err2025-12-23
err0
errOAAI
errMaj-Britt Paulsohn; Klara Henrike Frahnert; Denise Schlösser; Joana Oschwald; Waltraut Kopp; Xin Fang; Carolin Schneider; Constanza Tapia Contreras; Adi Danieli-Mackay; Fabian Ludewig; Martina Bleyer; Gabriela Salinas; Günter Schneider; Elisabeth Hessmann; Matthias Dobbelstein
err分享
err收藏
Inhibitors of pyrimidine synthesis synergize with N4-hydroxycytidine to diminish influenza virus replication嘧啶合成抑制剂与N4-羟基胞嘧啶协同作用以抑制流感病毒复制
errAntiviral Research
IF4
err2025-10-03
err0
errOAAI
errLeon Schrell; David Scheibner; Antje Dickmanns; Kim M. Stegmann; Lukas Mathias Michaely; Annika Graaf-Rau; Philip Beer; Andrew Parker; Sandra Diederich; Anne Balkema-Buschmann; Matthias Dobbelstein
err分享
err收藏
The protease inhibitor Nirmatrelvir synergizes with inhibitors of GRP78 to suppress SARS-CoV-2 replication蛋白酶抑制剂Nirmatrelvir与GRP78抑制剂协同作用以抑制SARS-CoV-2复制
errAntiviral Research
IF4
err2025-07-29
err0
errOAAI
errDoha Al Krad; Kim M. Stegmann; Antje Dickmanns; Priya Kumar; Claudia Blaurock; Björn-Patrick Mohl; Sina Jasmin Wille; Angele Breithaupt; Tobias Britzke; Anne Balkema-Buschmann; Matthias Dobbelstein
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Synergistic interference with SARS-CoV-2 replication by molnupiravir-derived N4-hydroxycytidine and inhibitors of CTP synthetase in cell culture细胞培养中，莫奈拉韦衍生的N4-羟基胞嘧啶与CTP合成酶抑制剂协同干扰SARS-CoV-2的复制。
errVirology
IF2.4
err2025-06-26
err0
errOAAI
errKim M. Stegmann; Antje Dickmanns; Hannah L. Fuchs; David Scheibner; Björn-Patrick Mohl; Florian R. Moeselaken; Wencke Reineking; Theresa Störk; Asisa Volz; Philip A. Beer; Andrew E. Parker; Veronika Pilchova; Christian Meyer zu Natrup; Maren von Köckritz-Blickwede; Wolfgang Baumgärtner; Anne Balkema-Buschmann; Matthias Dobbelstein
err分享
err收藏
Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro
errCELL DEATH & DISEASE
IF9.6
err2025-01-06
err0
errOAAI
errLotz, Rebecca; Osterburg, Christian; Chaikuad, Apirat; Weber, Sabrina; Akutsu, Masato; Machel, Anne Christin; Beyer, Ulrike; Gebel, Jakob; Loehr, Frank; Knapp, Stefan; Dobbelstein, Matthias; Lu, Xin; Doetsch, Volker
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MDM4 exon skipping upon dysfunctional ribosome assemblyMDM4外显子跳读在功能失调的核糖体组装中的作用
errTrends in Cell Biology
IF18.1
err2024-11-07
err0
PREAI
errJennifer Jansen; Matthias Dobbelstein
err分享
err收藏
ENGOT-ov48/EUDARIO: European trial on enhanced DNA repair inhibition in ovarian cancerENGOT-ov48/EUDARIO：欧洲增强DNA修复抑制在卵巢癌中的临床试验
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errConcin, N.; Van Gorp, T.; Lorusso, D.; Ray-Coquard, I. L.; Laenen, A.; Zamagni, C.; Harter, P.; Sehouli, J.; Raspagliesi, F.; Zeimet, A. G.; Lotz, J-P.; Salutari, V.; Tredan, O.; Zeillinger, R.; Dobbelstein, M.; Moll, U.; Kramer, D.; Obermayr, E.; Braicu, I.; Vergote, I. B.
err分享
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The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
errCELL REPORTS
IF6.9
err2024-08-01
err1
errOAAI
errJansen, Jennifer; Bohnsack, Katherine E.; Boehlken-Fascher, Susanne; Bohnsack, Markus T.; Dobbelstein, Matthias
err分享
err收藏
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design
errNATURE COMMUNICATIONS
IF15.7
err2024-01-09
err5
errOAAI
errFunk, Lisa-Marie; Poschmann, Gereon; von Pappenheim, Fabian Rabe; Chari, Ashwin; Stegmann, Kim M.; Dickmanns, Antje; Wensien, Marie; Eulig, Nora; Paknia, Elham; Heyne, Gabi; Penka, Elke; Pearson, Arwen R.; Berndt, Carsten; Fritz, Tobias; Bazzi, Sophia; Uranga, Jon; Mata, Ricardo A.; Dobbelstein, Matthias; Hilgenfeld, Rolf; Curth, Ute; Tittmann, Kai
err分享
err收藏
DNA templated Click Chemistry via 5-vinyl-2'-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells
errLIFE SCIENCES
IF5.1
err2023-10-01
err4
PREAI
errLi, Yizhu; Ling, Yurong; Loehr, Morten O.; Chaabane, Sabrina; Cheng, Oh Wan; Zhao, Kaifeng; Wu, Chao; Buescher, Moritz; Weber, Jana; Stomakhine, Daria; Munker, Marina; Pientka, Ronja; Christ, Sarah B.; Dobbelstein, Matthias; Luedtke, Nathan W.
err分享
err收藏
The interplay of TARG1 and PARG protects against genomic instability
errCELL REPORTS
IF6.9
err2023-09-01
err7
errOAAI
errGroslambert, Josephine; Prokhorova, Evgeniia; Wondisford, Anne R.; Tromans-Coia, Callum; Giansanti, Celeste; Jansen, Jennifer; Timinszky, Gyula; Dobbelstein, Matthias; Ahel, Dragana; O'Sullivan, Roderick J.; Ahel, Ivan
err分享
err收藏
CDK4/6 inhibition confers protection of normal gut epithelia against gemcitabine and the active metabolite of irinotecan
errCELL CYCLE
IF3.4
err2023-06-02
err1
errOAAI
errBlume, Joshua; Claus, Luisa; Isermann, Tamara; Dickmanns, Antje; Conradi, Lena-Christin; Schulz-Heddergott, Ramona; Dobbelstein, Matthias
err分享
err收藏
Direct p53 transcriptional repression:: In vivo analysis of CCAAT-containing G2/M promoters
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err224
errOAAI
errImbriano, C; Gurtner, A; Cocchiarella, F; Di Agostino, S; Basile, V; Gostissa, M; Dobbelstein, M; Del Sal, G; Piaggio, G; Mantovani, R
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err收藏
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair二肽基肽酶9触发BRCA2降解并促进DNA损伤修复
errEMBO REPORTS
IF6.2
err2022-08-01
err15
errOAAI
errBolgi, Oguz; Silva-Garcia, Maria; Ross, Breyan; Pilla, Esther; Kari, Vijayalakshmi; Killisch, Markus; Spitzner, Melanie; Stark, Nadine; Lenz, Christof; Weiss, Konstantin; Donzelli, Laura; Gorrell, Mark D.; Grade, Marian; Riemer, Jan; Urlaub, Henning; Dobbelstein, Matthias; Huber, Robert; Geiss-Friedlander, Ruth
err分享
err收藏
MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progressionMDM2结合并泛素化PARP1以增强DNA复制叉进展
errCELL REPORTS
IF6.9
err2022-05-01
err18
errOAAI
errGiansanti, Celeste; Manzini, Valentina; Dickmanns, Antje; Dickmanns, Achim; Palumbieri, Maria Dilia; Sanchi, Andrea; Kienle, Simon Maria; Rieth, Sonja; Scheffner, Martin; Lopes, Massimo; Dobbelstein, Matthias
err分享
err收藏
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflictsMYCN将核外泌体复合物招募到RNA聚合酶II以防止转录复制冲突
errMOLECULAR CELL
IF16.6
err2022-01-01
err22
errOAAI
errPapadopoulos, Dimitrios; Solvie, Daniel; Baluapuri, Apoorva; Endres, Theresa; Ha, Stefanie Anh; Herold, Steffi; Kalb, Jacqueline; Giansanti, Celeste; Schuelein-Voelk, Christina; Ade, Carsten Patrick; Schneider, Cornelius; Gaballa, Abdallah; Vos, Seychelle; Fischer, Utz; Dobbelstein, Matthias; Wolf, Elmar; Eilers, Martin
err分享
err收藏
Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies
errLANCET INFECTIOUS DISEASES
IF31
err2021-08-09
err64
errOAAI
errGuettler, Thomas; Aksu, Metin; Dickmanns, Antje; Stegmann, Kim M.; Gregor, Kathrin; Rees, Renate; Taxer, Waltraud; Rymarenko, Oleh; Schuenemann, Juergen; Dienemann, Christian; Gunkel, Philip; Mussil, Bianka; Krull, Jens; Teichmann, Ulrike; Gross, Uwe; Cordes, Volker C.; Dobbelstein, Matthias; Goerlich, Dirk
err分享
err收藏
Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastomaAurora-a和ATR激酶的联合抑制导致MYCN扩增的神经母细胞瘤消退
errNATURE CANCER
IF28.5
err2021-02-11
err54
errOAAI
errRoeschert, Isabelle; Poon, Evon; Henssen, Anton G.; Dorado Garcia, Heathcliff; Gatti, Marco; Giansanti, Celeste; Jamin, Yann; Ade, Carsten P.; Gallant, Peter; Schuelein-Voelk, Christina; Beli, Petra; Richards, Mark; Rosenfeldt, Mathias; Altmeyer, Matthias; Anderson, John; Eggert, Angelika; Dobbelstein, Matthias; Bayliss, Richard; Chesler, Louis; Buechel, Gabriele; Eilers, Martin
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The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2020-09-28
err36
errOAAI
errMueller, Anne; Dickmanns, Antje; Resch, Claudia; Schaekel, Knut; Hailfinger, Stephan; Dobbelstein, Matthias; Schulze-Osthoff, Klaus; Kramer, Daniela
err分享
err收藏

研究方向

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合作学者
合作期刊
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Robert Huber
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H 指数: 129 · 论文数: 406
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