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Structure-based optimization of TEAD inhibitors: Exploring a novel subpocket near Glu347 for the treatment of NF2-mutant cancer 基于结构的TEAD抑制剂的优化:探索治疗NF2突变型癌症的新型亚口袋(靠近Glu347) Kim, Jin Kwan; Kim, Jinhyuk; Kim, Hadong; Jin, Haiyan; Yoo, Youngki; Fei, Xiang; Maeng, Han-Joo; Seo, Seung-Yong; Han, Gyoonhee; No, Kyoung Tai 分享 收藏
Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor Kim, Jinhyuk; Kim, Hadong; Kim, Jongwan; Cho, Seon Yeon; Moon, Sungho; Yoo, Youngki; Kim, Hanseong; Kim, Jin Kwan; Jeon, Hyejin; Namkung, Wan; Han, Gyoonhee; No, Kyoung Tai 分享 收藏
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Propolis suppresses atopic dermatitis through targeting the MKK4 pathway Cho, Ye-Ryeong; Han, Eui Jeong; Heo, Eun; Jayasinghe, Arachchige Maheshika Kumari; Won, Jihyun; Lee, Soohwan; Kim, Taegun; Kim, Sung-Kuk; Lim, Seokwon; Woo, Soon Ok; Han, Gyoonhee; Kang, Wonku; Ahn, Ginnae; Byun, Sanguine 分享 收藏
A newly developed PLD1 inhibitor ameliorates rheumatoid arthritis by regulating pathogenic T and B cells and inhibiting osteoclast differentiation Park, Jin-Sil; Yang, SeungCheon; Song, Doona; Kim, Sung-Min; Choi, JeongWon; Kang, Hye Yeon; Jeong, Ha Yeon; Han, Gyoonhee; Min, Do Sik; Cho, Mi-La; Park, Sung-Hwan 分享 收藏
Novel small molecule-mediated restoration of the surface expression and anion exchange activity of mutated pendrin causing Pendred syndrome and DFNB4 Jung, Jinsei; Noh, Shin Hye; Jo, Sungwoo; Song, Doona; Kang, Min Jin; Shin, Mi Hwa; Lee, Hyun Jae; Pyun, Jae-Chul; Namkung, Wan; Han, Gyoonhee; Lee, Min Goo; Choi, Jae Young 分享 收藏
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CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2 Ryu, Yeong Chan; Park, Jiyeon; Kim, You-Rin; Choi, Sehee; Kim, Geon-Uk; Kim, Eunhwan; Hwang, Yumi; Kim, Heejene; Han, Gyoonhee; Lee, Soung-Hoon; Choi, Kang-Yell 分享 收藏
Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy Kim, Minjee; Kim, Hyeyoung; Kang, Bu-Gyeong; Lee, Jooyoung; Kim, Taegun; Lee, Hwanho; Jung, Jane; Oh, Myung Joon; Seo, Seungyoon; Ryu, Myung-Jeom; Sung, Yeojin; Lee, Yunji; Yeom, Jeonghun; Han, Gyoonhee; Cha, Sun-Shin; Jung, Hosung; Kim, Hyun Seok 分享 收藏
Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling Ryu, Yeong Chan; Kim, You-Rin; Park, Jiyeon; Choi, Sehee; Ryu, Won-Ji; Kim, Geon-Uk; Kim, Eunhwan; Hwang, Yumi; Kim, Heejene; Han, Gyoonhee; Lee, Soung-Hoon; Choi, Kang-Yell 分享 收藏
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Novel positive allosteric modulator of protease-activated receptor 1 promotes skin wound healing in hairless mice Seo, Yohan; Heo, Yunkyung; Jo, Sungwoo; Park, So-Hyeon; Lee, Chulho; Chang, Jiwon; Jeon, Dong-Kyu; Kim, Tae Gun; Han, Gyoonhee; Namkung, Wan 分享 收藏