Cynthia Wolberger - Publications, H-index & Citations

Cynthia Wolberger

Johns Hopkins University School of Medicine

61H指数

243论文数

1.7W被引数

收录论文 62

发表时间

Mechanism of USP21 autoinhibition and histone H2AK119 deubiquitination USP21的自抑制机制和组蛋白H2AK119的去泛素化

Science Advances

IF12.5

2025-10-10

PREAI

Sanim Rahman; Chad W. Hicks; Alexander Gwizdala; Cynthia Wolberger

A needed nomenclature for nucleosomes 核小体所需的命名法

Molecular Cell

IF16.6

2025-10-02

PREAI

Michael-Christopher Keogh; Genevieve Almouzni; Andrew J. Andrews; Karim-Jean Armache; Cheryl H. Arrowsmith; Sung Hee Baek; Mark T. Bedford; Emily Bernstein; Jacques Côté; Yael David; John M. Denu; Beat Fierz; Benjamin A. Garcia; Karen C. Glass; Or Gozani; Kristian Helin; Steven Henikoff; Ole N. Jensen; Steven Z. Josefowicz; Neil L. Kelleher; Tatiana G. Kutateladze; Herbert H. Lindner; Chao Lu; Karolin Luger; Parag Mallick; Catherine A. Musselman; Tom W. Muir; Ljiljana Paša-Tolić; Robert Schneider; Xiaobing Shi; Yang Shi; Simone Sidoli; Lloyd M. Smith; Jessica K. Tyler; Cynthia Wolberger; Jerry L. Workman; Brian D. Strahl; Nicolas L. Young

An intrinsically disordered region of Ubp10 regulates its binding and activity on ubiquitinated histone substrates Ubp10的一个固有无序区域调节其对泛素化组蛋白底物的结合和活性

Protein Science

IF5.2

2025-07-26

PREAI

Anneliese M. Faustino; Melesse Nune; Raquel Merino-Urteaga; Edgar Manriquez-Sandoval; Matthew Poyton; Taekjip Ha; Cynthia Wolberger; Stephen D. Fried

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch 泛素化组蛋白H2B作为核小体酸性斑块的守门人

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-16

OAAI

Hicks, Chad W.; Rahman, Sanim; Gloor, Susan L.; Fields, James K.; Husby, Natalia Ledo; Vaidya, Anup; Maier, Keith E.; Morgan, Michael; Wolberger, Cynthia

Breaking the K48-chain: linking ubiquitin beyond protein degradation 打破K48-chain: 连接泛素超越蛋白质降解

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-02-16

PREAI

Rahman, Sanim; Wolberger, Cynthia

Mechanism of histone H2B monoubiquitination by Bre1 Bre1对组蛋白H2B单脱基的作用机制

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-10-23

OAAI

Zhao, Fan; Hicks, Chad W.; Wolberger, Cynthia

Diverse modes of regulating methyltransferase activity by histone ubiquitination 通过组蛋白泛素化调节甲基转移酶活性的多种模式

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-10-01

OAAI

Fields, James K.; Hicks, Chad W.; Wolberger, Cynthia

Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome 与H2B-ubiquitinated核小体结合的MLL1-WRAD复合物的多态结构

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-09-12

OAAI

Rahman, Sanim; Hoffmann, Niklas A.; Worden, Evan J.; Smith, Marissa L.; Namitz, Kevin E. W.; Knutson, Bruce A.; Cosgrove, Michael S.; Wolberger, Cynthia

Role of the SWIRM Domain in Regulating the HAT Module of the SAGA Complex

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Haile, Sara T.; Wolberger, Cynthia

Potent macrocycle inhibitors of the human SAGA deubiquitinating module 人类SAGA去泛素化模块的有效大环抑制剂

CELL CHEMICAL BIOLOGY

IF7.2

2022-04-01

OAAI

Morgan, Michael; Ikenoue, Tatsuya; Suga, Hiroaki; Wolberger, Cynthia

The ASCC2 CUE domain in the ALKBH3-ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-02-01

OAAI

Lombardi, Patrick M.; Haile, Sara; Rusanov, Timur; Rodell, Rebecca; Anoh, Rita; Baer, Julia G.; Burke, Kate A.; Gray, Lauren N.; Hacker, Abigail R.; Kebreau, Kayla R.; Ngandu, Christine K.; Orland, Hannah A.; Osei-Asante, Emmanuella; Schmelyun, Dhane P.; Shorb, Devin E.; Syed, Shaheer H.; Veilleux, Julianna M.; Majumdar, Ananya; Mosammaparast, Nima; Wolberger, Cynthia

How structural biology transformed studies of transcription regulation 结构生物学如何转变转录调控研究

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Wolberger, Cynthia

Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome H2B-ubiquitinated核小体的COMPASS识别的结构基础

ELIFE

IF0

2020-01-10

OAAI

Worden, Evan J.; Zhang, Xiangbin; Wolberger, Cynthia

Activation and regulation of H2B-Ubiquitin-dependent histone methyltransferases

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2019-12-01

OAAI

Worden, Evan J.; Wolberger, Cynthia

FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics 事实和Ubp10合作调节H2B去泛素化和核小体动力学

ELIFE

IF0

2019-01-25

OAAI

Nune, Melesse; Morgan, Michael T.; Connell, Zaily; McCullough, Laura; Jbara, Muhammad; Sun, Hao; Brik, Ashraf; Formosa, Tim; Wolberger, Cynthia

OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination OTUB1通过防止E2泛素结合酶UBE2E1的自泛素化而非催化性稳定

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-11-01

OAAI

Pasupala, Nagesh; Morrow, Marie E.; Que, Lauren T.; Malynn, Barbara A.; Ma, Averil; Wolberger, Cynthia

Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins 活性位点丙氨酸突变将去泛素酶转化为高亲和力泛素结合蛋白

EMBO REPORTS

IF6.2

2018-08-27

OAAI

Morrow, Marie E.; Morgan, Michael T.; Clerici, Marcello; Growkova, Katerina; Yan, Ming; Komander, David; Sixma, Titia K.; Simicek, Michal; Wolberger, Cynthia

Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins 钯促使按需半胱氨酸化学合成具有挑战性和独特修饰的蛋白质

NATURE COMMUNICATIONS

IF15.7

2018-08-08

OAAI

Jbara, Muhammad; Laps, Shay; Morgan, Michael; Kamnesky, Guy; Mann, Guy; Wolberger, Cynthia; Brik, Ashraf

Hydrazide Mimics for Protein Lysine Acylation To Assess Nucleosome Dynamics and Deubiquitinase Action

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-07-10

OAAI

Bhat, Shridhar; Hwang, Yousang; Gibson, Matthew D.; Morgan, Michael T.; Taverna, Sean D.; Zhao, Yingming; Wolberger, Cynthia; Poirier, Michael G.; Cole, Philip A.

A Tunable Brake for HECT Ubiquitin Ligases HECT泛素连接酶的可调制动器

MOLECULAR CELL

IF16.6

2017-05-01

OAAI

Chen, Zan; Jiang, Hanjie; Xu, Wei; Li, Xiaoguang; Dempsey, Daniel R.; Zhang, Xiangbin; Devreotes, Peter; Wolberger, Cynthia; Amzel, L. Mario; Gabelli, Sandra B.; Cole, Philip A.

研究方向